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Poison is a Skill Tag in Path of Exile 2 (PoE 2). Read on to learn what skills and gems that have the Poison tag, the affixes, Uniques, and what Poison is!
List of Contents
Poison is an Ailment that deals Chaos damage over time and lasts 2 seconds by default. Damage from Poison bypasses Energy Shield.
Physical and Chaos damage from Hits Contribute to Poison Magnitude.
Damage does not Contribute to Poison chance, so it cannot be inflicted without an explicit source of Poison chance. The base Magnitude of Poison is Chaos damage per second dealt by the Hit that inflicted it. This is calculated using the final damage dealt by the Hit, but not any modifiers on the target that affect how much damage they will take from the Hit. This magnitude is not further affected by any modifiers to the damage you deal.
Modifiers and Debuffs that affect the enemy's ability to mitigate damage (such as Shock) can affect the damage the enemy takes from Poison, but any such modifiers that specifically apply to Hit damage (such as Penetration) do not affect Poison damage.
| Name | Implicit and Modifiers |
|---|---|
Atsak's Sight Veiled Mask Helmet |
Fixed Modifiers:
・30-40% increased Critical Hit Chance ・+10-20 to Dexterity ・+10-20 to Intelligence ・Critical Hits Poison the enemy ・100-150% increased Evasion and Energy Shield |
Lycosidae Rampart Tower Shield Shield |
Grants Skill:
・Raise Shield Fixed Modifiers: ・30-40% increased Block Chance ・60-100% increased Armour ・Accuracy Rating is Doubled ・Blocking Damage Poisons the enemy as though dealing 100 Base Chaos Damage |
Quatl's Molt Serpentscale Coat Body Armour |
Fixed Modifiers:
・+60-80 to maximum Life ・+17-23% to Chaos Resistance ・10-20 Life Regeneration per second ・Cannot be Poisoned ・60-80% increased Evasion Rating |
Plaguefinger Gauze Wraps Gloves |
Fixed Modifiers:
・30-40% increased Evasion and Energy Shield ・4-6% increased Attack Speed ・20-30% chance to Poison on Hit ・All Damage from Hits Contributes to Poison Magnitude |
Snakebite Spined Bracers Gloves |
Fixed Modifiers:
・40-60% increased Evasion Rating ・+7-17% to Chaos Resistance ・20-30% chance to Poison on Hit ・Targets can be affected by +1 of your Poisons at the same time ・6-10 Life Regeneration per second |
| We're still checking out the affixes. Please come back for more updates! |
| We're still checking out this skill tag. Please come back for more updates! |
| Skill | Effect |
|---|---|
Crippling Toxins |
・25% chance for Attacks to Main on Hit against Poisoned Enemies ・25% increased Magnitude of Poison you inflict |
Low Tolerance |
・60% increased Effect of Poison you inflict on targets that are not Poisoned |
Stacking Toxins |
・Targets can be affected by +1 of your Poisons at the same time ・20% reduced Magnitude of Poison you inflict |
Lasting Toxins |
・10% increased Skill Effect Duration ・50% increased Poison Duration |
Leeching Toxins |
・30% increased Magnitude of Poison you inflict ・Recover 2% of Life on Killing a Poisoned Enemy |
Building Toxins |
・25% reduced Poison Duration ・Targets can be affected by +1 of you Poisons at the same time |
Escalating Toxins |
・10% increased Poison Duration for each Poison you have inflicted Recently, up to a maximum of 100% |
Coated Knife |
・Critical Hits with Daggers have a 25% chance to Poison the Enemy |
| Poison Chance | ・X% chance to Poison on Hit |
| Poison Duration | ・X% increased Poison Duration |
| Poison Damage | ・X% increased Magnitude of Poison you Inflict |
Passive Skill Tree Guide and List of Passives
| Gem | Effects |
|---|---|
Gas Grenade
|
Impact: ・Impact radius is 1.5 meters ・Fuse duration is 2 seconds Poison Cloud: ・Attack Damage: 128% ・Does not Hit, but Poisons enemies as though Hitting them ・Gains 20% more radius per second, up to a maximum of 80% ・Cloud radius is 1.5 meters Explosion: ・Attack Damage: 342% ・Converts 100% of Physical Damage to Fire Damage |
Poisonburst Arrow
|
None |
Toxic Domain
|
Toxic Bloom: ・Toxic Bloom is 3 metres ・Toxic Bloom duration is 8 seconds ・Each Enemy can have up to 1 Pustule attached ・Regenerate 27.27 Life per Second ・Skill costs are increased by 25% ・Projectile hits attach a Pustule. Pustule Explosion: ・Attack Damage: 84% ・Always Poisons on Hit ・Pustule Detonation Rradius is 1.6 metres ・Pustule Detonates after 6 seconds ・Pustules store expected Damage of Poisons inflicted on them and will Detonate early after storing 23610 Poison Damage ・Stored Poison grants up to 300% more Explosion Damage. |
Toxic Growth
|
Attack: ・0.7 Seconds to Total Attack Time ・Fires 6 Arrows ・Stored Poison adds up to 1.5 metres to base explosion radius ・Stored Poison grants up to 100% more explosion damage ・Explosion Radius is 0.8 metres ・Maximum Pustule Duration is 15 seconds ・Maximum Pustule Limit is 6 |
Vine Arrow
|
・Impact Radius is 0.8 Metres |
| Gem | Effects |
|---|---|
Admixture
|
・20% more Magnitude of Bleeding inflicted by Supported Skills against Poisoned Enemies ・20% more Magnitude of Poison Inflicted by Supported Skills against Bleeding Enemies. |
Bursting Plague
|
・Poison from supported skills also adds 200% of damage per second to enemy as Plague, up to a maximum of 10% of enemy's maximum life. |
Corrosion
|
・Poison applied by supported skills also break armour equal to 80% of Poison damage dealt. |
Deadly Poison I
|
・Supported Skills deal 25% less damage with Hits ・75% more Magnitude of Poison inflicted with Supported Skills |
Deadly Poison II
|
・Supported Skills deal 30% less Damage with Hits ・100% more Magnitude of Poison inflicted with Supported Skills |
Malady
|
・Base Bleed chance instead applies to Poison for Supported Skills ・Base Poison chance instead applies to Bleed for Supported Skills |
Poison I
|
・Supported skills have 40% chance to Poison on hit |
Poison II
|
・Supported Skills have 60% chance to Poison on Hit |
Poison III
|
・Supported Skills have 60% chance to Poison on Hit ・20% more magnitude of Poison inflicted by Supported Skills against Bleeding Enemies. |
| Gem | Effects |
|---|---|
Herald of Plague
|
・Spreads the most damaging Poison on enemies you kill in a 1.7 metre radius ・22% chance to hinder enemies on spreading Poison on them |
Plague Bearer
|
・Stores 4% of Expected Poison damage ・Stores up to 197 Poison Damage |
Ravenous Swarm
|
・Swarms attack within 4 metre radius of you ・Swarm duration is 6.6 seconds ・Spawn a new Swarm once every 6 seconds ・Limit active 3 Swarms. |

Glossary and Basic Game Mechanics
Poison Explained



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