Path of Exile 2 (PoE 2) has a myriad of diverse Act and Pinnacle bosses. See the bosses for the campaign and the endgame here.

List of Bosses

Main Bosses

Boss	Location	Reward
The Rust King	Act 1 The Red Vale	・ Rune Skull Cap (Secrets in the Dark quest item)
Draven, the Eternal Praetor	Act 1 Mausoleum of the Praetor	・ Draven's Memorial Key Piece (Sorrow Among Stones)
Lachlann of Endless Lament	Act 1 Cemetery of the Eternals	・ Count Lachlann's Ring (The Mysterious Shade quest item)
The Executioner	Act 1 Ogham Village	・ The Trail of Corruption main quest progression
Count Geonor	Act 1 Ogham Manor	・ The Mad Wolf of Ogham main quest completion
Asinia, Praetor Consort	Act 1 Tomb of the Consort	・ Sorrow Among Stones main quest progression
The Bloated Miller	Act 1 The Riverbank	・ Mercy for the Miller main quest completion
Jamanra, the Risen King	Act 2 The Halani Gates	・ The Trail of Corruption main quest progress
Jamanra, the Abomination	Act 2 Dreadnought Vanguard	・ The Trail of Corruption quest completion
Azarian, the Forsaken Son	Act 2 Buried Shrines	・ The City of Seven Waters quest progress
Ekbab, Ancient Steed	Act 2 The Bone Pits	・ Mastodon Tusks (A Theft of Ivory quest item)
Tor Gul, the Defiler	Act 2 The Spires of Deshar	・ The Trail of Corruption main quest progress ・ Unlocks the Ascent to Power quest
Zalmarath, the Colossus	Act 2 The Titan Grotto	・ The Flame Ruby (A Crown of Stone quest item)
Rathbreaker	Act 2 Vastiri Outskirts	・ Earning Passage quest progression
Rudja, Dread Engineer	Act 2 Mawdun Mine	・ The Trail of Corruption quest progress
Zicoatl, Warden of the Core	Act 3 Jiquani's Sanctum	・ Large Soul Core (Legacy of the Vaal quest item)
Blackjaw, the Remnant	Act 3 Jiquani's Machinarium	・ The Flame Core - Grants +10% to Fire Resistance
Xyclucian, the Chimera	Act 3 Chimeral Wetlands	・ Chimeral Inscribed Ultimatum (Unlocks Trial of Chaos) ・ Legacy of the Vaal main quest progression
Queen of Filth	Act 3 Apex of Filth	・ Temple Door Icon (Legacy of the Vaal quest item)
Ketzuli, High Priest of the Sun	Act 3 Temple of Topec	・ Legacy of the Vaal main quest progression
Viper Napuatzi	Act 3 Utzaal	・ Legacy of the Vaal main quest progression
Doryani	Act 3 The Black Chambers	・ Legacy of the Vaal main quest progression

Optional Bosses

Boss	Location	Reward
The Devourer	Act 1 Mud Burrow	・ Treacherous Ground quest completion
The Brambleghast	Act 1 The Grelwood	・ Uncut Skill Gem Level 2
The Crowbell	Act 1 The Hunting Grounds	・ Book of Specialization - Grants two Weapon Set Passive Skill Points ・ Cruel: Book of Specialization - Grants two Weapon Set Passive Skill Points
The King in the Mists	Act 1 Freythorn	・ Gembloom Skull - Grants +30 Maximum Spirit ・ Spirit Skill Gem Level 4
Candlemass, the Living Rite	Act 1 Ogham Manor	・ Candlemass' Essence - Grants +20 Maximum Life ・ Cruel: Candlemass' Essence - Grants 8% Increased Maximum Life
Beira of the Rotten Pack	Act 1 Clearfell	・ Head of the Winter Wolf - Grants +10% to Cold Resistance ・ Cruel: Head of the Winter Wolf - Grants +10% to Cold Resistance
The Rotten Druid	Act 1 The Grim Tangle	・ Uncut Support Gem
Areagne, Forgotten Witch	Act 1 The Grelwood	・ Uncut Support Gem ・ Uncut Skill Gem
Vargir the Feral Mutt	Act 1 Ogham Farmlands	・ Uncut Skill Gem
Ashar, the Sand Mother	Act 2 Trial of Sekhemas	・ Floor 3 completion of the Trial of the Sekhemas ・ 3rd set of Ascendancy Points
Terracota Sentinels	Act 2 Trial of Sekhemas	・ Floor 2 completion of the Trial of the Sekhemas ・ 2nd set of Ascendancy Points
Watchful Twins	Act 2 Deshar	・ Djinn Barya
The Ninth Treasure of Keth	Act 2 The Lost City	・ Random Jewel
Rattlecage, the Earthbreaker	Act 2 Trial of Sekhemas	・ Floor 1 completion of the Trial of the Sekhemas
Kabala, Constrictor Queen	Act 2 Keth	・ Book of Specialization - Grants two Weapon Set Passive Skill Points
L'im the Impaler	Act 2 The Halani Gates	・ Rare Items
Balbala, The Traitor	Act 2 Traitor's Passage	・ Balbala's Barya - Allows access to the Trial of Sekhemas
Rootdredge	Act 3 Sandswept Marsh	・ Uncut Skill Gem Level 9
Ignagduk, the Bog Witch	Act 3 The Azak Bog	・ Gemrot Skull - Grants +30 Maximum Spirit ・ Ignagduk's Ghastly Spear (Tribal Vengeance quest item)
Mektul, the Forgemaster	Act 3 The Molten Vault	・ The Hammer of Kamasa (Treasures of Utzaal quest item)
Sisters of Garukhan	Act 3 The Spires of Deshar	・ Grants +10% to Lightning Resistance
Bahlak, the Sky Seer	Act 3 Temple of Chaos	・ Trial of Chaos progression
Chetza, the Feathered Plague	Act 3 Temple of Chaos	・ Trial of Chaos progression
Uxmal, the Beastlord	Act 3 Temple of Chaos	・ Trial of Chaos progression
Mighty Silverfist	Act 3 Jungle Ruins	・ Book of Specialization - Grants two Weapon Set Passive Skill Points ・ Cruel: Book of Specialization - Grants two Weapon Set Passive Skill Points

Pinnacle Bosses

Boss	How to Encounter
Arbiter of Ash The Burning Monolith	Use the keys obtained from the Iron, Copper, and Stone Citadels to unlock the encounter with the Arbiter of Ash in the Burning Monolith.
Zarokh, the Temporal Trial of the Sekhemas	Reach the last room on the 4th floor of the Trial of the Sekhemas with a Djinn Barya that has an Area Level of at least 74.
The Trialmaster Trial of Chaos	Use the three different Fate key items that you can obtain in the Trial of Chaos to open the door at the end of the 10th trial.
Xesht, We That Are One Breach	Use a Breachstone in a Realm Gate. When in the Breach Domain, defeat enough monsters in the Breach before the time runs out to be able to reach Xesht, We That Are One.
Olroth, Origin of the Fall Expedition	You'll encounter Olroth, Origin of the Fall by destroying the Kalguran Tomb that randomly appears in high-level Expedition Logbooks.
Omniphobia, Fear Manifest Delirium	Omniphobia, Fear Manifest, along with Kosis, the Revelation, randomly spawn in higher Simulacrum waves, with a guaranteed chance to spawn by the last few waves.
The King in the Mists Ritual	Use An Audience with the King which you can purchase in Ritual Altars to fight the endgame version of The King in the Mists.

General Boss Tips

General Tips to Defeat Bosses
Wear the Appropriate Charms Use Better Gear Base Resistances are Important Make Small Upgrades to your Gear

Wear the Appropriate Charms

Charms are the most versatile equipment slot in your arsenal and can be easily swapped for others to aid you in reducing the damage you take, or granting you immunity to ailments that could lead to your death.

Use Better Gear Base Types

The modifiers on your armors are not the only important thing to look out for when upgrading your equipment. Also consider the amount of base defenses (Armor, Energy Shield, or Evasion) a piece of armor can provide which helps in surviving fights. Better weapon Base Types also have better damage stats or Spells which can be crucial to increasing your damage potential.

Resistances are Important

Never underestimate getting as much Resistances you can get from your gear as they can greatly decrease the damage you take from Elemental and Chaos damage. Rings are a great way to start to get more Resistances since Sapphire, Ruby, and Topaz rings give Resistances as their Implicit Modifier.

Make Small Upgrades to your Gear

Don't forget that there are multiple ways to upgrade your gear to prepare for a boss. Adding Quality to your gear with Blacksmith Whetstones or Armorer Scraps, adding sockets with Artificer Orbs to slot in Runes, or adding Explicit Modifiers through different Crafting Currencies all good ways prepare for a difficult fight.

How Many Bosses are There?

Over a Hundred and More to Come

Path of Exile 2 will feature over 100 bosses, as confirmed by the Game Directors in various pre-release videos. Future expansions will continue to add even more, ensuring a steadily growing roster of challenging encounters.

50 Bosses in the Early Access

At the start of Early Access, the game will include 50 bosses. This reduced number is due to the removal of Acts 4 to 6, allowing the developers to concentrate on the Atlas endgame content. While unconfirmed, additional bosses may be introduced during the Early Access period, which is expected to last at least six months.

Path of Exile 2 (PoE 2) Related Guides

Path of Exile 2 Guides

Path of Exile 2 Wiki Contents
Builds	Classes
Tips and Tricks	Bosses
Walkthrough	Quests
Gems	Items
Weapons	Armors
Accessories	Passives
Skills	Ascension Trials
Glossary	Atlas of Worlds
Leagues	Characters
Cosmetics	Microtransactions
News and Updates	-

Best Class Tier List	Best Stash Tabs to Buy
Which Class Should You Play?	List of Unique Equipment
Best Minions to Summon	How to Use Loot Filters
Diablo 4 Player's Guide to PoE 2	-