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Path of Exile 2 (PoE 2)

Tribal Medicine Quest Walkthrough

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This is a guide for Tribal Medicine, a Side quest in Path of Exile 2 (PoE 2). Learn more about how to unlock Tribal Medicine, complete its objectives, all of Kaimana's locations, and its quest rewards here!

How to Unlock Tribal Medicine

Defeat the Great White One in Whakapanu Island

Great White One Boss Fight
You can immediately unlock the Tribal Medicine quest by picking up the Shark Fin quest item. This item can be obtained by defeating the Great White One boss in Whakapanu Island, Act 4.

Tribal Medicine Objectives

Quest Objectives
1 Defeat the Great White One
2 Find a Use for the Shark Fin

Defeat the Great White One

Sail to Whakapanu Island and look for the Shark Pit, a sandy open area in the island. Go near the edge of the pit near the water to trigger the Great White One boss fight. Upon defeating the boss, pick up the Shark Fin quest item and return to the ship.

How to Get and Use Shark Fin

Find a Use for the Shark Fin

Kaimana Located in Ngakanu

The next step is to find Kaimana and turn over the Shark Fin to complete the quest.

Kaimana's location changes depending on your progression of Act 4's main quest. Below are the three locations:

Karui Village, Ngakanu

Map
Overworld

Kaimana can be found at the Karui village in Ngakanu if you have not defeated The Excavation boss, Benedictus, First Herald.

Medicine Circle POI, Ngakanu

Map
Overworld

If you have defeated Benedictus, First Herald, Kaimana can be found at the Medicine Circle point of interest deep inside Ngakanu.

Karui Ship, Kingsmarch

Map
Overworld

If you finish The Search quest, Kaimana can be found on the Karui ship in the southern area of Kingsmarch.

Tribal Medicine Rewards

Quest Rewards

Rewards
・Level 11 Uncut Skill Gem, or
・ Level 11 Uncut Spirit Gem, or
・ Level 4 Uncut Support Gem

Completing the Tribal Medicine quest grants these rewards. You can obtain them after completing a certain objective or by completing the entire quest.

Path of Exile 2 Related Guides

POE 2 Quest Partial Banner
List of All Quests

Other Quests

Priority Quests

All Priority Quests
Ascent to Power

Hidden Quests

All Hidden Quests
Mushrooms Quest Idols Quest

Other Quest Guides

All Other Quest Guides
All Skill Point Quests -

All Main Quests

Act 1
Reaching Clearfell Secrets in the Dark
The Mysterious Shade Sorrow Among Stones
The Trail of Corruption The Mad Wolf of Ogham
Earning Passage -
Act 2
The City of Seven Waters A Theft of Ivory
A Crown of Stone -
Act 3
Legacy of the Vaal -
Act 4
The Search Whakapanu Island
Abandoned Prison Shrike Island
Land of the Kin -
Interlude
Recruit the Ezomytes Recruit the Maraketh
Recruit the Vaal -
Endgame
Cataclysm's Wake The Pinnacle of Flame
Vaal Incursion Faridun Foray
Ezomyte Infiltration The Fallen Hero
Mysterious Altars The Shadow Trickster
Into the Breach Precursor Towers
Extraplanar Invasion The Grand Quest

All Side Quests

Act 1
Treacherous Ground Finding the Forge
The Lost Lute Ominous Altars
The Hunt Begins Ancient Beacons
Act 2
Ancient Vows Tradition's Toll
Act 3
The Slithering Dead Tribal Vengeance
Act 4
Dark Mists Forgotten Bounty
Tribal Medicine Hostile Takeover
Trial of the Ancestors -
Interlude
Clearing the Way Howling Winds

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