Path of Exile 2 (PoE 2)

Viper Napuatzi Boss Guide

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Viper Napuatzi is an Act 3 Main Boss in Path of Exile 2 (PoE 2). See the location, the drops or rewards, and tips on how to beat Viper Napuatzi here.

Viper Napuatzi Location

Act 3 - Utzaal

Path of Exile 2 - Viper Napuatzi Location

You'll find Viper Napuatzi and her Legion Blockade at the end of the Utzaal area found in the second part of Act 3.

Viper Napuatzi How to Beat

Tips on Beating Viper Napuatzi

Dodge Roll in Rhythm During the Spears Phase to Avoid Damage

Aside from the heavy Poison damage Viper can deal, her legion’s spear phase poses a significant challenge. The best strategy is to Dodge Roll in a consistent rhythm, regardless of when an attack seems imminent. This method ensures you remain safe without second-guessing your timing.

Stay Close to the Shield

Alternatively, you can get close to shield and watch out if the shield beside you lights up green. This way, you'll have an easier time spotting the shields that glow and are preparing to attack.

Watch Out for the Seventh Attack

The seventh attack in this phase is a sweeping wave of spear strikes originating from one side. Its starting point is random, but you can spot it by the glowing spears. Stay alert and Dodge Roll toward the wave's origin as it approaches.

Get Chaos and Poison Damage Reduction

Path of Exile 2 - Viper Get an Antidote Charm or an Amethyst Ring

Viper is perhaps the first difficult boss that deals most of their damage as Chaos damage. You will constanly get Poisoned in this fight and get hit by Chaos damage. It's heavily recommended to bring an Antidote Charm for Poison Immunity and a good source of Chaos Resistance, such as Amethyst Rings.

Alternatively, Just Get More Life Modifiers

Since Chaos Resistance is a difficult stat to get, the next best defensive you can get on your gear is as much Life as you can, especially during the campaign.

Viper Napuatzi Moveset

Viper Napuatzi Moves Mode
Spear Mode Unarmed Mode

Spear Moves

Moves Details & How to Dodge
“Yaomac take you!”
or
“Serpent's Bite!”
Unblockable Poison Spear

Viper charges up a poison spear and lunges it at you. This attack has a delay so be careful dodging early.
“Storm of Xopec!”
or
“Xopec's spear!”
Lightning Spear

Charges up a Lightning-infused spear wher the projectiles that split returns to Viper. Dodge Roll sideways to avoid the returning projectiles.
“Bow to your Queen, or die!”
or
“The Viper strikes”
or
“I will not relent!”
Spear Combos

Viper has a two sets of melee combos that are similar to each other. Keep your distance and Dodge Roll the last hit to avoid getting hit.
Quiksteps
Viper has a couple of quickstep moves that can also be followed up with quick attacks. These moves are fast but fortunately doesn't do much damage.
“You will fall before us!”
Toxic Spear Totem

Sticks her spear to the ground which leaves a constant pool of poison. Viper continues to No Spear Mode and changes movesets.

Unarmed Moves

Moves Details & How to Dodge
“Feel Arakali's sting!”
or
“Arakali's web!”
Spear Barrage

Random spearmen will start thrusting their spears in succession. It's best to keep dodging in rhythm if reacting to each attack becomes too demanding.
Fire and Chaos Meteors
Channels a spell that continually rains fire and chaos meteors to the arena. Stay aware of the red and purple marks on the ground to determine which spots are safe to move to during this phase
“I shall crush you, insect!”
Poison Slam

Jumps high in the air and slams to the ground for big damage. Move and Dodge Roll away once she jumps to avoid this attack.
Lingering Snakes
Summons a number of poison snake projectile to roam the arena for a time that deals damage when you get hit. It'll be tough to dodge this move with other attacks at the same time, prioritize focusing other deadly attacks before focusing on avoiding these.
Poison Shots
Shots a barrage of poison projectils and follows it up with a burst of them. Sidestep the rapid shots then Dodge Roll forward to avoid the last burst of projectiles.

Viper Napuatzi Overview and Rewards

Basic Info

Path of Exile 2 - Viper Napuatzi Act 3 Boss
Location Act 3
Utzaal
Resistances ・ Physical
・ Fire
・ Cold
・ Lightning
Weaknesses ・ None
Damage Types ・ Physical
・ Chaos
・ Fire
Debuffs ・ Poison
・ Caustic Ground

Rewards

・ Legacy of the Vaal main quest progression

Defeating Viper Napuatzi grants these rewards upon defeat, either as direct drops or as a quest completion bonus.

Path of Exile 2 (PoE 2) Related Guides

Path of Exile 2 - All Bosses Partial Banner
List of Bosses

Other Boss Guides
All Spirit Bosses -

All Act 1 Bosses

The Bloated Miller The Devourer Beira of the Rotten Pack
Areagne, Forgotten Witch The Brambleghast The Rust King
The Rotten Druid Draven, the Eternal Praetor Asinia, Praetor Consort
Lachlan of Endless Lament The King in the Mists The Crowbell
Vargir the Feral Mutt The Executioner Candlemass, the Living Rite
Count Geonor - -

All Act 2 Bosses

Rathbreaker Rudja, Dread Engineer Balbala, The Traitor
L'im the Impaler Jamanra, the Risen King Kabala, Constrictor Queen
Zalmarath, the Colossus Tor Gul, the Defiler Ekbab, Ancient Steed
The Ninth Treasure of Keth Azarian, the Forsaken Son Watchful Twins
Jamanra, the Abomination Sisters of Garukhan -

All Act 3 Bosses

Rootdredge Mighty Silverfist Blackjaw, the Remnant
Xyclucian, the Chimera Zicoatl, Warden of the Core Ignagduk, the Bog Witch
Mektul, the Forgemaster Queen of Filth Ketzuli, High Priest of the Sun
Viper Napuatzi Doryani -

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