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Path of Exile 2 (PoE 2)

Courtesan Mannan's Rune of Cruelty Effects and How to Get

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Courtesan Mannan's Rune of Cruelty is an Endgame Rune in Path of Exile 2 (PoE 2). See how to get Courtesan Mannan's Rune of Cruelty and an overview of the item.

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List of Contents

How to Get Courtesan Mannan's Rune of Cruelty

Use Currency Exchange

Use Currency Exchange

Courtesan Mannan's Rune of Cruelty can be obtained by visiting the Currency Exchange NPC in every Act. Currency Exchange becomes available after completing Act 3.

Currency Exchange Explained

How to Use Courtesan Mannan's Rune of Cruelty

Socket into Equipment

Socket into Equipment

Courtesan Mannan's Rune of Cruelty is used by inserting it unto equipment with empty sockets to apply its effects on the specified equipment. Its effects will change depending on whether or not you inserted it into Armor or Weapon.

Courtesan Mannan's Rune of Cruelty can be replaced with another Rune or Soul Core, but replacing your socketed Runes will cause the Rune to be destroyed.

Courtesan Mannan's Rune of Cruelty Overview

Effects and Basic Info

Courtesan Mannan Courtesan Mannan's Rune of Cruelty Item Details
Type: Endgame Rune
Max Stack Size: 10
Description
Gloves: 15% increased Magnitude of Damage Ailments you inflict

Path of Exile 2 Related Guides

List of Items

List of Items

List of Items

Items by Type
Currency Quest Items Distilled Emotions Flasks
Runes Jewels Tablets Relics
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Omens Waystones Special Items Talismans
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List of Endgame Runes

Hedgewitch Assandra Hedgewitch Assandra's Rune of Wisdom Saqawal Saqawal's Rune of the Sky Fenumus Fenumus' Rune of Agony
Farrul Farrul's Rune of Grace Farrul Farrul's Rune of the Chase Craiceann Craiceann's Rune of Warding
Saqawal Saqawal's Rune of Memory Saqawal Saqawal's Rune of Erosion Farrul Farrul's Rune of the Hunt
Craiceann Craiceann's Rune of Recovery Courtesan Mannan Courtesan Mannan's Rune of Cruelty Thane Grannell Thane Grannell's Rune of Mastery
Fenumus Fenumus' Rune of Spinning Countess Seske Countess Seske's Rune of Archery Thane Girt Thane Girt's Rune of Wildness
Fenumus Fenumus' Rune of Draining Thane Myrk Thane Myrk's Rune of Summer Lady Hestra Lady Hestra's Rune of Winter
Thane Leld Thane Leld's Rune of Spring The Greatwolf The Greatwolf's Rune of Claws The Greatwolf The Greatwolf's Rune of Willpower

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