Path of Exile 2 (PoE 2)

How to Get Inspiration Rune

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Inspiration Rune is a Rune in Path of Exile 2 (PoE 2). See how to get Inspiration Rune and an overview of the item.

List of Contents

How to Get Inspiration Rune

Dropped by Enemies

PoE 2 - Monster Drop
Inspiration Rune has a chance to drop randomly while defeating enemies you encounter. These items can drop at any point in the game.

Use Currency Exchange

Use Currency Exchange

Inspiration Rune can also be obtained by visiting the Currency Exchange NPC in every Act. Currency Exchange becomes available in Cruel Difficulty which is unlocked after completing Act 3 on Normal difficulty.

Currency Exchange Explained

How to Use Inspiration Rune

Socket into Equipment

Socket into Equipment

Inspiration Rune is used by inserting it into equipment with empty sockets to apply its effects. It provides different effects, depending on the equipment it is inserted into.

Inspiration Rune Overview

Effects and Basic Info

Inspiration Rune Icon Inspiration Rune Item Details
Type: Rune
Description
Weapon: Gain 10 Mana per Enemy Killed
Armour: 15% increased Mana Regeneration Rate

Path of Exile 2 Related Guides

List of Items

List of Items

List of Items

Items by Type
Currency Quest Items Distilled Emotions Flasks
Runes Jewels Tablets Relics
Soul Cores Essences Charms Catalysts
Omens Waystones Special Items -

List of Runes

Glacial Rune Icon Glacial Rune Storm Rune Icon Storm Rune Desert Rune Icon Desert Rune
Iron Rune Icon Iron Rune Body Rune Icon Body Rune Mind Rune Icon Mind Rune
Vision Rune Icon Vision Rune Rebirth Rune Icon Rebirth Rune Inspiration Rune Icon Inspiration Rune
Stone Rune Icon Stone Rune

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