Path of Exile 2 (PoE 2)

Distilled Despair Effects and How to Get

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Distilled Despair is a Distilled Emotion in Path of Exile 2 (PoE 2). See how to get Distilled Despair and an overview of the item.

List of Contents

How to Get Distilled Despair

Obtained from Deliriums

Reward from Deliriums

Distilled Despair is dropped by enemies found in the Delirium endgame activity. Deliriums spawn waves of enemies where you'll need to defeat as much of them as possible and can be found in the Atlas of Worlds.

Delirium Endgame Guide

Use Currency Exchange

Use Currency Exchange

Distilled Despair can also be obtained by visiting the Currency Exchange NPC in every Act. Currency Exchange becomes available in Cruel Difficulty which is unlocked after completing Act 3 on Normal difficulty.

Currency Exchange Explained

How to Use Distilled Despair

Instill Notables to Amulets

Instill Notables to Amulets

Distilled Despair is used by right-clicking it to open the Instilling menu and then applying a Notable Passive to an Amulet.

List of Accessories

Distilled Despair Overview

Effects and Basic Info

Distilled Despair Icon Distilled Despair Item Details
Type: Distilled Emotion
Max Stack Size: 10
Description
Can be combined with other Distilled Emotions to instill amulets with Notable Passive Skills or Waystones with layers of Delirium.

Path of Exile 2 Related Guides

List of Items

List of Items

List of Items

Items by Type
Currency Quest Items Distilled Emotions Flasks
Runes Jewels Tablets Relics
Soul Cores Essences Charms Catalysts
Omens Waystones Special Items -

List of Distilled Emotions

Distilled Ire Icon Distilled Ire Distilled Guilt Icon Distilled Guilt Distilled Disgust Icon Distilled Disgust
Distilled Greed Icon Distilled Greed Distilled Paranoia Icon Distilled Paranoia Distilled Envy Icon Distilled Envy
Distilled Despair Icon Distilled Despair Distilled Fear Icon Distilled Fear Distilled Suffering Icon Distilled Suffering
Distilled Isolation Icon Distilled Isolation

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