Diablo 4's Endgame content features many activities that can efficiently max out your build. Read on to learn more about the best Endgame loop you can do, how to reach it, and what it is here!

Best Endgame Loop for Season 7

The best endgame loop for Season 7 Guide (Season of Witchcraft) features efficient content with the highest possible Gear and Materials you can get in a single loop. The endgame loop is as follows:

1. Focus on Headhunt Whispers
2. Clear Rootholds
3. Defeat Ladder and Uber Bosses
4. Run Infernal Horde for Obducite
5. Push for Higher Tier Pit Runs
6. Repeat

Focus on Headhunt Whispers

Headhunts are the main Seasonal Content you can farm for different items and materials, especially Restless Rot and Fugitive Heads, which are required for crafting or upgrading Witchcraft Powers and Occult Gems. Upon entering a Headhunt, do the easier Whispers first until you spawn and defeat the Husk boss for 5 Grim Favours. Afterwards, you can switch to a new Headhunt and clear the other easier Whispers there. Doing it this way helps you skip the less efficient Whispers such as Patrol or Wisps.

Most importantly, clearing Whispers for Whisper Caches and opening the Silent Chests in Headhunts can help you farm Whispering Woods, which are the keys required to access Rootholds.

Headhunt Explained

Clear Rootholds

Rootholds are new mini dungeons with a risk/reward system that can drop tons of loot and is the best way to farm Restless Rot and Fugitive Heads. The drops are similar to the Exposed Roots you encounter in Headhunts but they drop more and better loot much more consistently.

On higher Torment tiers, you can consistenly farm Boss Summoning Materials from both Headhunts and Rootholds which you can use in the future.

Rootholds Dungeon Guide

Defeat Ladder and Uber Bosses

List of Boss Loot Tables
Lord Zir	Varshan	Grigoire
The Beast in the Ice	Duriel	Andariel

Once you have all the Boss Summoning Materials you need, take on any of the bosses above to target farm the Unique gear you are looking for to complete your build.

We recommend doing at least 2 runs for Ladder Bosses so you have enough materials for summoning Duriel with Mucus-Slick Egg and Shard of Agony, and Andariel with Sandscorched Shackles and Pincushioned Dolls.

Uber Boss Loot Tables (Season 7)

Run Infernal Horde for Obducite

After you start getting the equipment needed for your build, start Masterworking them at the Blacksmith by farming materials from the Infernal Horde as it can drop large amounts of Obducite, Iron Chunks, and Rawhide.

If ever you run out of Infernal Compasses, you can always head back to step 2 and keep opening Whisper Caches to help farm for them and continue doing Infernal Horde runs.

How to Get Obducite

Push for Higher Tier Pit Runs

Once you have upgraded your equipment, start pushing for higher Tier Pit runs to unlock Torment IV difficulty and upgrade your Glyphs.

If you still have missing equipment for your build, you can target farm Bosses first before taking on The Pit as this is a time-based dungeon that requires you clear it fast in order to level up your Glyphs.

The Pit Guide and Location

How to Reach Endgame

Level Up to 60 and Clear The Pit Tier 20

In order to reach the endgame of Diablo 4, you first have to level up to 60 and start doing Pit runs up to Tier 20. Once you clear Tier 20, the first Torment difficulty will unlock and you can immediately switch to it.

Keep in mind that enemies have more health and your armor and resistances are be reduced here so try to get the necessary items for your build first before doing higher difficulties.

Diablo 4 Related Guides

List of Seasons: How Do Seasons Work?

Season 7 Guides

Season Guides