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Diablo 4: Vessel of Hatred (D4)
All Alchemist Features
★ NEW: Season 10 Guide | Season 10 Release Date
┗ Seasonal Content: Chaos Rifts | New Uniques
┗ Seasonal Mechanic: List of Chaos Perks & Chaos Armor
★ Season 10 Best Builds & Best Chaos Perks
★ Check out our Vessel of Hatred expansion guide
The Alchemist is an NPC in Diablo 4 (D4) that allows players to craft Gem fragments, upgrade their health potions, craft powerful elixirs and incenses, and refine surplus resources. Read on to learn more about the Alchemist and its features including how to unlock the Alchemist during your playthrough!
All Alchemist Features
| Click on a Link to Jump to a Section! | |
|---|---|
| Health Potion Upgrading | Elixir Crafting |
| Transmutation | Incense Crafting |
Health Potion Upgrading
One of the Alchemist's most important features is health potion upgrading as it allows you to improve the potency of your character's health potion. Spend Crafting Materials and Gold to upgrade your health potion after hitting certain level milestones during your playthrough.
| List of All Potions | ||
|---|---|---|
 Tiny Healing Potion
|
 Minor Healing Potion
|
 Light Healing Potion
|
 Moderate Healing Potion
|
 Strong Healing Potion
|
 Greater Healing Potion
|
 Major Healing Potion
|
 Superior Healing Potion
|
|
How to Upgrade the Healing Potion
Elixir Crafting
The Alchemist also allows players to craft Elixirs that can boost different stats and increase your characters survivability during combat. Additionally, most Elixirs featured offer increased experience gain, perfect for power-leveling and quickly reaching endgame.
Transmutation
Gems
| Gem Transmutation Requirements | |
|---|---|
| Amethyst Fragment | ・Topaz ・Diamond ・Ruby |
| Diamond Fragment | ・Amethyst ・Emerald ・Skull |
| Emerald Fragment | ・Amethyst ・Topaz ・Skull |
| Ruby Fragment | ・Amethyst ・Topaz ・Sapphire |
| Sapphire Fragment | ・Diamond ・Ruby ・Skull |
| Skull Fragment | ・Emerald ・Sapphire ・Skull |
| Topaz Fragment | ・Emerald ・Sapphire ・Ruby |
Gem fragments can now be transmuted to form Gem fragments of another type. This process requires you to transmute three other Gem types in order to craft your desired gem.
Summoning Item
You can craft summoning items needed for Echo of Varshan in the Alchemist. This would require you to exchange other Varshan summoning materials and convert them into any of the other materials, except for Malignant Hearts.
Crafting Materials
You can now also craft Obducites in the Eternal Realm by using your leftover Ingolith and Neathiron, which were previously obtained from The Pit. As of Season 6, Ingolith and Neathiron are no longer obtainable materials.
Masterworking Guide and How to Unlock
Incense Crafting
Incense can be used to apply a certain buff to the user and all nearby players. Only one Incense can be active at any given time and all Incense will only be active for 20 minutes.
Additionally incenses provide a bonus to experience gains and their effects persist after death.
Alchemist Location
Found in Major Locations in Sanctuary
| Alchemist Locations |
|---|
|
・ Major Cities ・ Citadel ・ Tree of Whispers ・ Training Areas |
The Alchemist can be located in almost all major locations in Sanctuary, including cities, the Citadel, the Tree of Whispers, and also the Training Area. You won’t be able to change builds mid-dungeon or during other content unless you return to these locations.
Interactive Map: All Regions in Sanctuary
How to Unlock the Alchemist
Complete the Prologue and Arrive at Kyovashad
To unlock the Alchemist, players will simply need to complete the main story Prologue of Diablo 4. This will unlock Kyovashad and the Alchemist NPC available inside the city.
Reach Level 5 to Unlock the Alchemist Priority Quest
To unlock the priority quest Health Potion Upgrading, you will first need to reach Level 5. After doing so, the quest will automatically unlock, setting a waypoint to an Alchemist that will walk you through the steps of upgrading your Health Potion for the first time.
Diablo 4 Related Guides
All NPC Vendors
| All NPC Vendors | ||
|---|---|---|
 Blacksmith |
 Alchemist |
 Occultist |
 Jeweler |
 Purveyor of Curiosities |
 Stable Master |
 Dark Citadel Vendor |
||
| All PvP NPC Vendors | ||
 Cursed Scroll Vendor |
 Odd and Ends |
 Unconventional Mount Armor |
 Unsavory Oddities |
||
Author
All Alchemist Features
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