Diablo 4: Vessel of Hatred (D4)

All Alchemist Features

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Diablo 4 - All Alchemist Features

The Alchemist is an NPC in Diablo 4 (D4) that allows players to craft Gem fragments, upgrade their health potions, craft powerful elixirs and incenses, and refine surplus resources. Read on to learn more about the Alchemist and its features including how to unlock the Alchemist during your playthrough!

All Alchemist Features

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Health Potion Upgrading Elixir Crafting
Transmutation Incense Crafting

Health Potion Upgrading

Diablo 4 - Alchemist Health Potion Upgrading

One of the Alchemist's most important features is health potion upgrading as it allows you to improve the potency of your character's health potion. Spend Crafting Materials and Gold to upgrade your health potion after hitting certain level milestones during your playthrough.

List of All Potions
Tiny Healing PotionTiny Healing Potion Minor Healing PotionMinor Healing Potion Light Healing PotionLight Healing Potion
Moderate Healing PotionModerate Healing Potion Strong Healing PotionStrong Healing Potion Greater Healing PotionGreater Healing Potion
Major Healing PotionMajor Healing Potion Superior Healing PotionSuperior Healing Potion

How to Upgrade the Healing Potion

Elixir Crafting

Diablo 4 - Alchemist Elixir Crafting

The Alchemist also allows players to craft Elixirs that can boost different stats and increase your characters survivability during combat. Additionally, most Elixirs featured offer increased experience gain, perfect for power-leveling and quickly reaching endgame.

List of All Elixirs
Elixir of AdvantageElixir of Advantage Elixir of Advantage IIElixir of Advantage II Elixir of AntiveninElixir of Antivenin
Elixir of Cold ResistanceElixir of Cold Resistance Elixir of Cold Resistance IIElixir of Cold Resistance II Elixir of DestructionElixir of Destruction
Elixir of Destruction IIElixir of Destruction II Elixir of Fire ResistanceElixir of Fire Resistance Elixir of Fire Resistance IIElixir of Fire Resistance II
Elixir of FortitudeElixir of Fortitude Elixir of Fortitude IIElixir of Fortitude II Elixir of Iron BarbsElixir of Iron Barbs
Elixir of Iron Barbs IIElixir of Iron Barbs II Elixir of Lightning ResistanceElixir of Lightning Resistance Elixir of Lightning Resistance IIElixir of Lightning Resistance II
Elixir of Poison ResistanceElixir of Poison Resistance Elixir of Poison Resistance IIElixir of Poison Resistance II Elixir of PrecisionElixir of Precision
Elixir of Precision IIElixir of Precision II Elixir of ResourcefulnessElixir of Resourcefulness Elixir of Resourcefulness IIElixir of Resourcefulness II
Elixir of Shadow ResistanceElixir of Shadow Resistance Elixir of Shadow Resistance IIElixir of Shadow Resistance II

Transmutation

Gems

Gem Transmutation Requirements
Amethyst Fragment ・Topaz
・Diamond
・Ruby
Diamond Fragment ・Amethyst
・Emerald
・Skull
Emerald Fragment ・Amethyst
・Topaz
・Skull
Ruby Fragment ・Amethyst
・Topaz
・Sapphire
Sapphire Fragment ・Diamond
・Ruby
・Skull
Skull Fragment ・Emerald
・Sapphire
・Skull
Topaz Fragment ・Emerald
・Sapphire
・Ruby

Gem fragments can now be transmuted to form Gem fragments of another type. This process requires you to transmute three other Gem types in order to craft your desired gem.

List of All Gems

Summoning Item

You can craft summoning items needed for Echo of Varshan in the Alchemist. This would require you to exchange other Varshan summoning materials and convert them into any of the other materials, except for Malignant Hearts.

Crafting Materials

You can now also craft Obducites in the Eternal Realm by using your leftover Ingolith and Neathiron, which were previously obtained from The Pit. As of Season 6, Ingolith and Neathiron are no longer obtainable materials.

Masterworking Guide and How to Unlock

Incense Crafting

Diablo 4 - Alchemist Incense Crafting

Incense can be used to apply a certain buff to the user and all nearby players. Only one Incense can be active at any given time and all Incense will only be active for 20 minutes.

Additionally incenses provide a bonus to experience gains and their effects persist after death.

List of All Incense
Chorus of WarChorus of War Spiral MorningSpiral Morning Ancient TimesAncient Times
SageSage's Whisper QueenQueen's Supreme Blessed GuideBlessed Guide
Reddamine BuzzReddamine Buzz Soothing SpicesSoothing Spices Scents of the Desert AfternoonScents of the Desert Afternoon
Storm of the WildsStorm of the Wilds Desert EscapeDesert Escape Song of the MountainSong of the Mountain
Spirit DanceSpirit Dance

List of All Consumables

How to Unlock the Alchemist

Complete the Prologue and Arrive at Kyovashad

Diablo 4 - Play Through the Prologue

To unlock the Alchemist, players will simply need to complete the main story Prologue of Diablo 4. This will unlock Kyovashad and the Alchemist NPC available inside the city.

Where is Kyovashad?

Reach Level 5 to Unlock the Alchemist Priority Quest

Diablo 4 - Alchemist Priority Quest

To unlock the priority quest Health Potion Upgrading, you will first need to reach Level 5. After doing so, the quest will automatically unlock, setting a waypoint to an Alchemist that will walk you through the steps of upgrading your Health Potion for the first time.

Diablo 4 Related Guides

Diablo 4 - NPCs Partial Banner

List of All NPCs

All NPC Vendors

All NPC Vendors
BlacksmithBlacksmith AlchemistAlchemist OccultistOccultist
JewelerJeweler Purveyor of CuriositiesPurveyor of Curiosities StablemasterStable Master
Dark Citadel Vendor Dark Citadel Vendor
All PvP NPC Vendors
Cursed Scroll VendorCursed Scroll Vendor Odd and EndsOdd and Ends Unconventional Mount ArmorUnconventional Mount Armor
Unsavory OdditiesUnsavory Oddities

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