The Alchemist is an NPC in Diablo 4 (D4) that allows players to craft Gem fragments, upgrade their health potions, craft powerful elixirs and incenses, and refine surplus resources. Read on to learn more about the Alchemist and its features including how to unlock the Alchemist during your playthrough!

All Alchemist Features

Health Potion Upgrading

One of the Alchemist's most important features is health potion upgrading as it allows you to improve the potency of your character's health potion. Spend Crafting Materials and Gold to upgrade your health potion after hitting certain level milestones during your playthrough.

List of All Potions
Tiny Healing Potion	Minor Healing Potion	Light Healing Potion
Moderate Healing Potion	Strong Healing Potion	Greater Healing Potion
Major Healing Potion	Superior Healing Potion

How to Upgrade the Healing Potion

Elixir Crafting

The Alchemist also allows players to craft Elixirs that can boost different stats and increase your characters survivability during combat. Additionally, most Elixirs featured offer increased experience gain, perfect for power-leveling and quickly reaching endgame.

List of All Elixirs
Elixir of Advantage	Elixir of Advantage II	Elixir of Antivenin
Elixir of Cold Resistance	Elixir of Cold Resistance II	Elixir of Destruction
Elixir of Destruction II	Elixir of Fire Resistance	Elixir of Fire Resistance II
Elixir of Fortitude	Elixir of Iron Barbs	Elixir of Iron Barbs II
Elixir of Lightning Resistance	Elixir of Lightning Resistance II	Elixir of Poison Resistance
Elixir of Poison Resistance II	Elixir of Precision	Elixir of Precision II
Elixir of Resourcefulness	Elixir of Resourcefulness II	Elixir of Shadow Resistance
Elixir of Shadow Resistance II

Transmutation

Gems

Gem fragments can now be transmuted to form Gem fragments of another type. This process requires you to transmute three other Gem types in order to craft your desired gem.

List of All Gems

Summoning Item

You can craft summoning items needed for Echo of Varshan in the Alchemist. This would require you to exchange other Varshan summoning materials and convert them into any of the other materials, except for Malignant Hearts.

Crafting Materials

You can now also craft Obducites in the Eternal Realm by using your leftover Ingolith and Neathiron, which were previously obtained from The Pit. As of Season 6, Ingolith and Neathiron are no longer obtainable materials.

Masterworking Guide and How to Unlock

Incense Crafting

Incense can be used to apply a certain buff to the user and all nearby players. Only one Incense can be active at any given time and all Incense will only be active for 20 minutes.

Additionally incenses provide a bonus to experience gains and their effects persist after death.

List of All Incense
Scents of the Desert Afternoon	Incense of Rushing Wind	Incense of Capacity
Incense of Fortitude	Incense of Khazra Power	Spirit Dance
Song of the Mountain	Desert Escape	Storm of the Wilds
Chorus of War	Soothing Spices	Reddamine Buzz
Blessed Guide	Queen's Supreme	Sage's Whisper
Ancient Times	Spiral Morning

List of All Consumables

Alchemist Location

Found in Major Locations in Sanctuary

The Alchemist can be located in almost all major locations in Sanctuary, including cities, the Citadel, the Tree of Whispers, and also the Training Area. You won’t be able to change builds mid-dungeon or during other content unless you return to these locations.

Interactive Map: All Regions in Sanctuary

How to Unlock the Alchemist

Complete the Prologue and Arrive at Kyovashad

To unlock the Alchemist, players will simply need to complete the main story Prologue of Diablo 4. This will unlock Kyovashad and the Alchemist NPC available inside the city.

Where is Kyovashad?

Reach Level 5 to Unlock the Alchemist Priority Quest

To unlock the priority quest Health Potion Upgrading, you will first need to reach Level 5. After doing so, the quest will automatically unlock, setting a waypoint to an Alchemist that will walk you through the steps of upgrading your Health Potion for the first time.

Diablo 4 Related Guides

List of All NPCs

All NPC Vendors

All NPC Vendors
Blacksmith	Alchemist	Occultist
Jeweler	Purveyor of Curiosities	Stable Master
Dark Citadel Vendor
All PvP NPC Vendors
Cursed Scroll Vendor	Odd and Ends	Unconventional Mount Armor
Unsavory Oddities