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Diablo 4 (D4)

How to Defeat the Blood Bishop: Boss Fight Guide

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Blood Bishop is the boss in Sanguine Chapel dungeon in Diablo 4 (D4). Learn everything you need to know to defeat him, such as his attack patterns, rewards, and where to find him down below!

List of Contents

How to Defeat the Blood Bishop

Study Blood Bishop's Moves

Outlaw Sharpshooter Attack Patterns
1 Volley
Blood Bishop conjures a volley of projectiles that all fly in the player's direction.
2 Blood Boils
Blood Bishop thrusts his tentacles into the ground and summons 4 boils that explode after a set amount of time.
3 Grab
Blood Bishop extends both his tentacles in an attempt to grab the player. If successful, this attack deals a significant amount of damage and heals the Blood Bishop for the amount of damage dealt.

Avoid Attacks

The Blood Bishop's attacks are relatively easy to telegraph due to their long wind-up animations. Focus on avoiding attacks as best you can to conserve HP potions and slowly whittle down his HP.

Don't Get Grabbed

The most punishing attack in the Blood Bishop's arsenal is his Grab attack. Not only does it deal a large amount of damage, it also heals the Blood Bishop for a significant amount. Avoid this attack at all costs.

Destroy the Blood Boils

Focus on destroying the Blood Boils whenever the Bishop summons them as this makes the fight much more manageable.

Use AoE Skills

Skills such as the Rogue's Barrage (As seen in the video) are effective countermeasures as they deal with all the boils simultaneously.

Blood Bishop Rewards

Quest Completion

Defeating Blood Bishop is a pre-requisite to completing the Blood Sermon side quest. Additionally, Blood Bishop will drop gold and equipment of varying rarities.

Blood Bishop Location

In Sanguine Chapel Dungeon

Diablo IV - Sanguine Chapel Entrance
View Full Size Image

You can find the Blood Bishop within the Sanguine Chapel dungeon, which unlocks during the events of the Blood Sermon Side Quest.
Blood Sermon Quest Walkthrough

Related Guides

Diablo 4 - Bosses

List of All Bosses

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Main Quest Bosses Stronghold Bosses
Dungeon Bosses Uber Bosses

All Uber Bosses and Required Materials

Uber Boss Required Materials
Lord Zir, The Dark Master ・Exquisite Blood
Echo of Varshan Malignant Body Parts:
・Gurgling Head
・Blackened Femur
・Trembling Hand
・Malignant Heart (WT4 only)
Grigoire, The Galvanic Saint ・Living Steel
Duriel, King of Maggots ・Mucus-Slick Egg
・Shard of Agony
The Beast in the Ice ・Distilled Fear
Uber Lilith None

All Bosses Per Region

Fractured Peaks Scosglen Dry Steppes
Kehjistan Hawezar

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Blood Bishop Bramble Broodguard
Chief Marauder Cyhrach The First Born Den Mother
Devoted Champion Drowned Seahag Elias
Innes, Vengeance of Glor-han-Fhaidha Khazra Abomination Mother's Judgment
Outlaw Sharpshooter Resurrected Malice Sarat
Scourge of the Land Seething Hivemaster Slither
Spiritcaller of Frost Spiritcaller of Squalls The Butcher
The Curator Tomb Lord

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