Uniques can be farmed by joining Helltides, defeating Uber Bosses, and completing Infernal Horde runs in Diablo 4 (D4). Read on to learn all the best Unique Item farming methods and all new methods added from Season 6!

How to Farm Uniques

1. Open Chests During Helltide

Helltides are the easiest activity to run in order to gain Uniques without having to sacrifice progression. Given they spawn every hour, Helltides will be your go-to Unique farming method.

However, do note that while these chests won't really guarantee a Unique drop, you will still need to run Helltides to get boss material drops. These mats allow you to target farm Uniques since they are used to summon Grigoire and, by extension, Duriel later on.

2. Defeat Uber Bosses to Target Farm Uniques

Defeating Uber Bosses is the next best method for farming Uniques quickly. Despite the activity being gated by the need to farm boss materials, the rewards are more than worth it especially since you have a chance to get high item power rares.

All Uber Bosses and Boss Loot Tables

Grigoire Loot Table

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Lord Zir Loot Table

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Duriel Loot Table

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The Beast in the Ice Loot Table

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Varshan Loot Table

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3. Complete Infernal Horde Runs

A new feature added to the game allows you to battle the forces of hell and gather Aether during battle. Spend these Aether after besting The Fell Council to redeem several Legendaries and Unique items!

While the Infernal Horde has a decent chance of giving out Uniques, the Unique they can drop are funneled towards the new Unique items introduced in Season 6.

Infernal Horde Guide and How to Unlock

4. Run Nightmare Dungeons

Running and completing Nightmare Dungeons will also give you a chance to get Unique Items. However, in order to make this a bit more efficient, only do this when you're looking to level up your Paragon Glyphs.

Since Nightmare Dungeons take a considerable amount of time to clear, you're better off running multiple Helltides instead (especially at max glyph levels) since these tie-in directly with farming boss materials for Duriel runs.

Nightmare Dungeon Guide

5. Purchase Items from the Purveyor of Curiosities

The Purveyor of Curiosities can drop Unique items together with its regular randomized wares. Choose the item type you want and buy them from the Purveyor of Curiosities for a chance to get the Unique gear you need!

All Purveyor of Curiosities Features

6. Obtain from Whisper Caches

The Tree of Whisper's Whisper Caches now also has a chance to drop unique items. We highly recommend not disregarding activities that can allow you to progress your Tree of Whisper activities for a chance to get Uniques as well as a ton of gold and crafting items!

How to Complete the Tree of Whispers

What Are Uniques and Mythic Uniques?

Uniques are High-Tier Items With Exclusive Effects

Unlike Legendary Items, Uniques are one step up in rarity, dropping with a fixed Aspect and set of Affixes. The Aspect and Affix set attached to Uniques are often build-defining, making these items highly sought after during the endgame.

List of Unique Items

Drops In Every World Tier with Varying Rarity

Unique items can drop in every difficulty but with varying chances. Obtaining the Unique Items in Torment difficulties have higher chances of being Ancestral with a greater affix.

Mythic Uniques are Super Rare Items with Powerful Effects

Mythic Uniques stand out because they have more powerful Aspects, compared to regular Unique items. As the name suggests, these are much more powerful but incredibly rare, and have an abysmally low drop rate.

List of All Mythic Uniques and How to Get

Diablo 4 Related Guides

Beginner Guides and Best Tips for Getting Started

Tips and Tricks