This is a Rogue Twisting Blades endgame build and guide for Season 7 of Diablo 4: Vessel of Hatred (D4). Read on to learn more about the Rogue Twisting Blades endgame build as well as its playstyle in the Season of Witchcraft!

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Rogue Twisting Blades Build

Poison Twisting Blades Build Summary

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Summary			Skills and Passives			Witchcraft			Aspects and Affixes
Gems			Mercenary			Paragon			Playstyle

Build Summary
Poison Twisting Blades Build
	Focus: Endgame, Pit 100+
Fast Mob Clearing High Mobility High Energy Costs

This leveling build for Season 7 uses Twisting Blades with Poison Imbuement and with Shadow Clone to quickly make work of enemy packs and speed run pit levels.

Poison Twisting Blades Skills and Passives

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Summary			Skills and Passives			Witchcraft			Aspects and Affixes
Gems			Mercenary			Paragon			Playstyle

※ More skills can be seen by scrolling vertically.

Active Skills
Basic Skill Tree ┗ Puncture (1/5) 　┗ Enhanced Puncture
Core Skill Tree ┗ Twisting Blades (5/5) 　┗ Enhanced Twisting Blades 　　┗ Advanced Twisting Blades ┗ Sturdy (3/3)
Agility Skill Tree ┗ Dash (1/5) 　┗ Enhanced Dash 　　┗ Methodical Dash ┗ Unstable Elixirs (3/3) ┗ Trick Attacks (3/3) ┗ Balestra (1/3)
Subterfuge Skill Tree ┗ Dark Shroud (5/5) 　┗ Enhanced Dark Shroud 　　┗ Countering Dark Shroud ┗ Smoke Grenade (1/5) 　┗ Enhanced Smoke Grenade 　　┗ Countering Smoke Grenade ┗ Exploit (3/3) 　┗ Malice (3/3)
Imbuement Skill Tree ┗ Poison Imbuement (5/5) 　┗ Enhanced Poison Imbuement 　　┗ Blended Poison Imbuement ┗ Deadly Venom (3/3) 　┗ Alchemical Advantage (3/3) ┗ Frigid Finesse (3/3)
Ultimate Skill Tree ┗ Shadow Clone (2/5) 　┗ Prime Shadow Clone ┗ Aftermath (2/3) ┗ Second Wind (3/3) ┗ Innervation (3/3)
Key Passive ┗ Alchemical Admixture

Poison Twisting Blades Specialization

Preparation is the best specialization for this Twisting Blades build variant as it allows the build to impale multiple Twisting Blades onto enemies, overwhelming them with poison damage. This also allows the build to manage its energy consumption and generation even if it's not using basic skills.

Best Witchcraft Powers

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Summary			Skills and Passives			Witchcraft			Aspects and Affixes
Gems			Mercenary			Paragon			Playstyle

Witchcraft	Effect Rank Up Bonus
Soul Harvest	Feed upon the life force of nearby enemies whenever you use a skill with a cooldown, increasing your primary stat by 3% per monster for X seconds. Rank 9: Soul Harvest does not lose duration so long as enemies are nearby.
Hex of Whispers	Dealing damage to an enemy afflicts them with Hex of Whispers that deals X Shadow damage the next time damage is dealt. Afterwards, Hex of Whispers will jump to another enemy up to a maximum of 6 times. Hex of Whispers may only be applied once every 5 seconds. Rank 7: After bouncing onto 6 enemies, the hex bounces back to you granting 15% Fortify and removing all crowd control and negative status effects.
Decay Augmentation	Your Witchcraft Effects deal X of the damage dealt over 5 seconds. The damage type is based on your class. Rank 10: When your damage-over-time effects exceed 85% of the target’s total Life, they immediately die.
Aura of Siphoning	Conjure an aura of decay that deals 80% Poison damage to enemies every second. Rank 10: Each time Aura of Siphoning deals damage, you are healed for 1% of Maximum Life.
The Cycle	Dealing any damage with your skills has a 15% chance to grow a flower from the ground. When an enemy is near, the flower deals X Poison damage to that enemy over 5 seconds. If an ally is near, the flower Heals for 6% Maximum Life. The flower withers away after use. A flower may grow once every 2 seconds per enemy. Rank 5: The damage and healing affects all enemies or allies near the flower. "
Aura Specialization	The size of your Aura Effects are increased by X. Rank 10: Increase the Critical Strike Damage by 50% against enemies inside your Aura Effects.

The Witchcraft setup for the build is focused on synergizing with the non-physical damage aspects of the build. Aura of Siphoning, Decay Augmentation, and Hex of Whispers contribute to the bonuses of Alchemical Admixture, while Soul Harvest provides a raw damage bonus by increasing Dexterity.

Depending on your preference, you can swap The Cycle with Piranhado if you want more crowd control.

List of All Witchcraft Powers

Poison Twisting Blades Best Aspects and Affixes

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Summary			Skills and Passives			Witchcraft			Aspects and Affixes
Gems			Mercenary			Paragon			Playstyle

Masterwork Priority	Affixes marked with ★ are the ones you should aim to upgrade when masterworking.

※ More gear Aspects can be seen by scrolling vertically.

Gear	Aspect and Affixes
Head	Aspect of Concussive Strikes ・Dexterity ・Ranks to Poison Imbuement ・Cooldown Reduction ★★★ Temper: ・Defensive - Rogue Persistence 　┗ Ranks to Second Wind ・Utility - Imbuement Abundance 　┗ Poison Imbue Lasts for 2 Casts
Chest	Shroud of Khanduras ・Evade Grants Movement Speed for 1.5 seconds ・Non-physical Damage ★★★ ・Ranks to Dark Shroud ・Shadow Resistance
Gloves	Fists of Fate ・Lucky Hit Chance ★★ ・Critical Strike Chance ・Attack Speed ・Lucky Hit: Chance to Apply a random Crowd Control effect ★
Pants	Umbrous Aspect ・Dexterity ・Maximum Life ・Armor Temper: ・Defensive - Rogue Persistence 　┗ Ranks to Second Wind ・Utility - Imbuement Abundance 　┗ Poison Imbue Lasts for 2 Casts ★★★
Boots	Rakanoth's Wake ・Cooldown Reduction ・Resistance to All Elements ・Movement Speed ・Non-physical Damage ★★★
Amulet	Aspect of Elements ・Damage ・Critical Strike Chance ・Movement Speed Temper: ・Offensive - Subterfuge Expertise 　┗ Damage per Dark Shroud Shadow ・Utility - Worldly Fortune 　┗ Lucky Hit: Chance to Freeze Enemies ★★★
Ring	Aspect of Corruption ・Critical Strike Chance ・Attack Speed ・Damage Over Time Temper: ・Offensive - Subterfuge Expertise 　┗ Damage per Dark Shroud Shadow ★★★ ・Resource - Worldly Stability 　┗ Resource Cost Reduction
Ring	Conceited Aspect ・Critical Strike Chance ・Attack Speed ・Damage Over Time Temper: ・Offensive - Subterfuge Expertise 　┗ Damage per Dark Shroud Shadow ★★★ ・Resource - Worldly Stability 　┗ Resource Cost Reduction
Crossbow	Aspect of Creeping Death ・Maximum Life ・Damage Over Time ・Dexterity Temper: ・Offensive - Subterfuge Expertise 　┗ Damage per Dark Shroud Shadow ★★ ・Weapons - Cuttthroat Augments 　┗ Chance for Twisting Blades to Hit Twice ★
1-Handed Sword	Aspect of Bursting Venoms ・Maximum Life ・Damage Over Time ・Dexterity Temper: ・Offensive - Subterfuge Expertise 　┗ Damage per Dark Shroud Shadow ★★ ・Weapons - Cuttthroat Augments 　┗ Chance for Twisting Blades to Hit Twice ★
1-Handed Sword	Bladedancer's Aspect ・・Maximum Life ・Damage Over Time ・Dexterity Temper: ・Offensive - Subterfuge Expertise 　┗ Damage per Dark Shroud Shadow ★★ ・Weapons - Cuttthroat Augments 　┗ Chance for Twisting Blades to Hit Twice ★

Poison Twisting Blades Best Gems and Occult Gems

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Summary			Skills and Passives			Witchcraft			Aspects and Affixes
Gems			Mercenary			Paragon			Playstyle

Weapon	Armor
Diamond	Emerald

For Gems, it's best to slot in Emerald on your Armor slots for more Dexterity. For your weapons, it's best to use Diamonds to increase the damage of your Ultimate Skill, synergizing with the No Witnesses passive.

List of All Gems

Poison Twisting Blades Best Occult Gems

Amulet	Ring	Ring
Vulture Talon	Dust Stone	Voice of the Stars

The Occult gem setup increases the build's overall damage by synergizing with the build's damage multipliers. Vulture Talon allows the build to proc Decay Augmentation for faster executions, while Dust Stone and Voice of the Stars provide raw damage bonuses.

List of All Occult Gems

Poison Twisting Blades Best Runewords

Runeword 1	Runeword 2
Poc Eom	Yul Lum

For our Runewords, Poc + Eom and Yul + Lum are our recommended choices as they solve the energy management problem that the build has. This allows you to cast spam all your skills for better engagements against mobs and bosses.

List of All Runewords

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Summary				Skill Progression				Witchcraft
Aspects and Affixes			Gems			Mercenary			Playstyle

Poison Twisting Blades Best Mercenary

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Summary			Skills and Passives			Witchcraft			Aspects and Affixes
Gems			Mercenary			Paragon			Playstyle

Mercenary	Reinforcement
Varyana	Raheir

Use Varyana as Your Main Mercenary

Varyana's passive effect allows us to efficiently clear dungeons and other activities due to the movement speed it grants, enablinging you to avoid ground effects while fighting.

For her skills, use Shockwave, Ancient Harpoons, and Iron Grip to synergize it with Smoke Grenade, allowing you to daze the enemies she pulled. Reprisal is also a great passive from Varyana as it provides an extra defense against impairment.

Varyana Mercenary Guide

Use Raheir For Reinforcement

Use Raheir's Bastion to grant passive Unstoppable for 1 second and redirect 90% of damage taken to Raheir.

Have Raheir's opportunity usage to Crowd Control to apply the Unstoppable from Bastion, granting you an extra dispel against impairment effects.

Raheir Mercenary Guide

Poison Twisting Blades Paragon Setup

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Summary			Skills and Passives			Witchcraft			Aspects and Affixes
Gems			Mercenary			Paragon			Playstyle

Paragon Boards
1. Starting Board (Bane)
2. Exploit Weakness (Canny)
3. No Witnesses (Versatility)
4. Eldritch Bounty (Tracker)
5. Cheap Shot (Control)

For your Paragon Board, you'll want to take runes and nodes that increase your Poisoning Damage and Non-Physical damage to synergize with Alchemical Admixture. The raw damage increase of the build comes from the No Witnesses node, which increases our skill's damage based on our Damage to Ultimate multipliers.

Poison Twisting Blades Playstyle and Rotation

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Summary			Skills and Passives			Witchcraft			Aspects and Affixes
Gems			Mercenary			Paragon			Playstyle

The playstyle of the Poison Twisting Blades revolves around spamming your Twisting Blades and Poison Imbuement when Bursting Venom procs to recast Shadow Clone. The rotation is as follows:

1. Cast Shadow Clone and spam Twisting Blades until Bursting Venom procs.
2. Spam Twisting Blades and Bursting Venoms.
3. Recast Shadow Clone.

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