Gig: Serious Side Effects Quest Walkthrough and Rewards | Cyberpunk 2077

★Patch 1.22 has been released!
Patch 1.22 (Hotfix 1.22)

New details revealed for Patches and DLC Content!
Update Roadmap for 2021

Did you find any bugs? Share and and get solutions!
List of Bugs (1013)

We're updating daily with new tips and information!
Story Walkthrough
All Side Quest Guides
Best Weapons
Romance Guide
Crafting Spec Locations

Cyberpunk 2077 Serious Side Effects Top.png

This is a walkthrough for Gig: Serious Side Effects, a Gig Quest in Cyberpunk 2077. Read on to learn all the available choices in Gig: Serious Side Effects, how to get the best possible result, tips and strategies for the Quest, and all available rewards.

Gig: Serious Side Effects Basic Information

Quest Type Gig
Act Act 2
Quest No.
Lifepath All

How to Unlock Gig: Serious Side Effects

Fast travel to MLK & Brandon and head to the nearest undiscovered side quest. Muamar El Capitan Reyes will call you to begin the gig.

Gig: Serious Side Effects Rewards

Quest Rewards 2940 Eddies

Gig: Serious Side Effects Walkthrough

Arroyo, Santo Domingo

Objective Icon.pngGo to the Dewdrop Inn.→Find the beta acid contianer.
Go to the Dewdrop Inn. There are two options here: (1) Go to the receptionist and book a room; or (2) Go around the building and climb the emergency stairs to force open the 2nd floor door.
Objective Icon.pngFind Booker Updike (optional).→Go to room 103 and find out what happened to Booker (optional).→Search room 103 (optional).
If you choose to book a room, you will be able to accomplish the optional objectives. Head to the ground floor rooms and bribe or force the technician there to enter Booker Updike's room. Investigate it to find more clues and then go to the room upstairs.
Objective Icon.pngGo to the room upstairs.→Look for the stolen beta acid in the lab.→Retrieve the beta acid container.
After the optional objectives or if you chose to go around the building, head to the room on the 2nd floor with a man who is busy with his braindance. Go to the terrace and cross all the way to the other end to gain access to the lab. Kill or incapacitate the nearest guy to your left and take the beta acid container directly beside him.
Objective Icon.pngGet out of the motel.→Deposit the beta acid in the Drop Point.
Jump off the 2nd floor and run towards the nearest drop off point. Wait for El Capitan to call you to end the gig.

Gig: Serious Side Effects Choices and Best Choice

Investigating Booker Updike

Investigate What Happened To Him

You will need to accomplish all optional objectives. You will spend an extra 1000 eddies in order to bribe the technician to open Booker Updike's room for you as well as payment for a room in the inn.

Finish The Mission Without Investigating

You can simply go around the back of the building, climb the emergency stairs and force open the 2nd floor door (needs Body Level 8). Head to the same last room as the original path and take the beta acid and finish the mission.

Best Choice

Accomplishing all objectives including the optional ones will be best here as this will ultimately put you in the good books of El Capitan.

All Completion Routes

Best Completion Route

Route Rating
Back Door ★★★★★
Side Alley ★★★★
Front Desk ★★★
Fire Escape ★★
Guns Blazing

Entering the hotel through the back door is the best option as it leads you almost directly to your objective. However, doing the optional objectives may require other routes.

Stealth Route Guide

Back Door

There's a back door that you can open if you have enough Technical Ability points. Once inside, you can sneak your way upstairs and into room 200 to hop over the railings until you reach room 203.

Side Alley

You can open the window on the west side of the hotel. Alternatively, you can force-open the shutters in the side alley to the north. The former will lead you to one of the optional objectives.

Front Desk

Enter the hotel through the main entrance and rent a room at the front desk. You will still have to avoid the enemies on the upper floor if you don't want to engage in combat.

Fire Escape

Head behind the hotel and go up the fire escape. There's a door at the top that you can open if you have sufficient Technical Ability points. This may be the riskiest stealth route, especially if you don't have enough points to force-open room 203.

Guns Blazing Route Guide

The best route to go through here would be the front entrance. Shoot your way from the front desk to the upper floor. There will be a handful of enemies in the building so be careful.

Obtainable Items

This list contains only significant items and those which have a high chance of appearing.

Item How to Get
Multilayered Maroon Scales Syn-Coated BomberMultilayered Maroon Scales Syn-Coated Bomber (Legendary) Found in a cache inside a closet on the ground floor. You need at least 3 Body points to get inside the closet.
Border Guard Ballistic Vest
Border Guard Ballistic Vest
Can be looted from the same container where the Beta Acid is.

Cyberpunk 2077 Story Walkthrough


Complete Story Walkthrough

All Gig Guides

Quest Quest Giver Rec. Level
Gig: An Inconvenient Killer Dino
Gig: A Lack of Empathy Dino
Gig: Backs Against The Wall Regina
Gig: Big Pete's Got Big Problems Dakota
Gig: Bring Me The Head of Gustavo Orta Padre -
Gig: Dancing on a Minefield Dakota
Gig: Eye for an Eye Padre -
Gig: Family Heirloom Rogue -
Gig: Family Matters El Capitan
Gig: Fixer, Merc, Soldier, Spy Regina -
Gig: For My Son El Capitan -
Gig: Freedom of The Press Regina Any
Gig: Getting Warmer... Wakako
Gig: Hacking The Hacker El Capitan
Gig: Life's Work Padre
Gig: MIA Dakota
Gig: No Fixers Dakota
Gig: Old Friends Padre
Gig: Olive Branch Wakako -
Gig: On a Tight Leash Padre
Gig: Psychofan Padre -
Gig: Race to The Top El Capitan -
Gig: Rite of Passage Regina
Gig: Scrolls Before Swine Regina
Gig: Serial Suicide Dino
Gig: Sparring Partner Dakota
Gig: Sr. Ladrillo's Private Collection Padre
Gig: The Frolics of Councilwoman Cole Dino
Gig: The Lord Giveth and Taketh Away Padre -
Gig: The Union Strikes Back Rogue
Gig: Two Wrongs Makes Us Right
Gig: Until Death Do Us Part Wakako
Gig: Wakako's Favorite Wakako
Gig: We Have Your Wife Wakako -
Gig: Welcome to America, Comrade Regina -
Gig: Tyger and Vulture Wakako 1
Gig: Troublesome Neighbors Regina 2
Gig: Bloodsport Regina 4
Gig: Trevor's Last Ride Dakota 5
Gig: Woman of La Mancha Regina 5
Cyberpsycho Sighting: Lt. Mower Regina 7
Cyberpsycho Sighting: Second Chances Regina 7
Cyberpsycho Sighting: Six Feet Under Regina 7
Cyberpsycho Sighting: Ticket to The Major Leagues Regina 7
Cyberpsycho Sighting: Where The Bodies Hit The Floor Regina 7
Cyberpsycho Sighting: Demons of War Regina 10
Cyberpsycho Sighting: Lex Talionis Regina 10
Cyberpsycho Sighting: Smoke on The Water Regina 10
Gig: Catch a Tyger's Toe Regina 10
Gig: Flight of the Cheetah Regina 10
Gig: Occupational Hazard Regina 10
Gig: Playing For Keeps Regina 10
Cyberpsycho Sighting: Bloody Ritual Regina 15
Cyberpsycho Sighting: Discount Doc Regina 15
Cyberpsycho Sighting: House on a Hill Regina 15
Cyberpsycho Sighting: The Wasteland Regina 15
Cyberpsycho Sighting: Under The Bridge Regina 15
Gig: Breaking News El Capitan 15
Gig: Dirty Biz Regina 15
Gig: Hippocratic Oath Regina 15
Gig: Last Login Regina 15
Gig: Lousy Kleppers Regina 15
Gig: Many Ways to Skin a Cat Regina 15
Gig: Monster Hunt Regina 15
Gig: Serious Side Effects El Capitan 15
Gig: Shark in the Water Regina 15
Gig: The Heisenberg Principle Regina 15
Gig: A Shrine Defiled Wakako 20
Gig: Cuckoo's Nest El Capitan 20
Gig: Error 404 El Capitan 20
Gig: Fifth Column Padre 20
Gig: Flying Drugs Dakota 20
Gig: Going Up or Down? Padre 20
Gig: Greed Never Pays Wakako 20
Gig: Severance Package El Capitan 20
Gig: Small Man, Big Evil Regina 20
Cyberpsycho Sighting: Letter of The Law Regina 25
Cyberpsycho Sighting: On Deaf Ears Regina 25
Cyberpsycho Sighting: Phantom of Night City Regina 25
Cyberpsycho Sighting: Seaside Cafe Regina 25
Gig: Goodbye, Night City Dakota 25
Gig: Going-Away Party El Capitan 30
Gig: Jeopardy Padre 30
Gig: Radar Love Dakota 30
Gig: Guinea Pigs Dino 35
Gig: Hot Merchandise Rogue 40

All Quest Types

Quest Types
Main Quests Side Quests Gigs

    The Like Feature

    You can save a comment for later by giving it a Like.
    As a member:Get access to several features!

    Opinions about an article or post go here.
    Opinions about an article or post
    We at Game8 thank you for your support.
    In order for us to make the best articles possible, share your corrections, opinions, and thoughts about "Gig: Serious Side Effects Quest Walkthrough and Rewards" with us!
    When reporting a problem, please be as specific as possible in providing details such as what conditions the problem occurred under and what kind of effects it had.

    Walkthrough Menu

    New Comment

    • In the crafting screen, would love to see a comparison between what I'm currently equipped with vs what I've selected to craft. In the Inventory screen, I have no idea where any extra weight is without going into each category (weapons, clothes, etc). Please add some sort of weight indicator next to each category so I know exactly where I seem to be overloaded. In the Map, please mark completed items (assault in progress, access points), grey out the icons or something similar?

    • When I grapple NPCs I can see black patches flashing on the back of their head, shoulders, and back. Like they are rendering properly.

    All rights reserved

    Back to the Top
    Cookies help us deliver our services. By using our services, you agree to our use of cookies. Learn more