Best Monowire Build for Patch 1.6 | Cyberpunk 2077

This is a guide to the Best Monowire Build for Cyberpunk 2077 Patch 1.6. Read our guide for details about the build, what attributes to level up, which perks to choose, and what weapons and cyberwares to use.

Monowire Build Overview

Build Basic Information

Strengths and Weaknesses

Monowire Best Attribute Build

Attribute Progression

Max out Reflexes first for the Blades perks and increased Crit Chance then max out Cool next for the Cold Blood perks and increased Crit Damage. You can max out Body last for extra damage and health bonus, since you already have healing perks and the monowire's high DPS to recover health and deal with enemies quickly, which are more than enough in the early game.

Monowire Build Best Perks

Blades (Reflexes)

Perk	Effect at Lv. 1
Dragon Strike	Increases Crit Damage with Blades by 40%. +1% per Perk level.
Sting Like a Bee	Increases attack speed with Blades by 10%.
Roaring Waters	Strong Attacks with Blades deal 10% more damage.
Crimson Dance	Combos with Blades have a 15% chance to apply Bleeding.
Slow and Steady	Moving while wielding a Blade increases Armor by 15%
Flight of the Sparrow	Reduces the Stamina cost of all attack with Blades by 30%
Stuck Pig	Increases Bleeding duration by 3 sec.
Blessed Blade	Increases Crit Chance with Blades by 10%.
Bloodlust	While wielding a Blade, recovers 2% Health when hitting an enemy affected by Bleeding.
Judge, Jury and Executioner	Increases damage with Blades by 50% against enemies with max Health.
Fiery Blast	Increases damage with Blades by 1% for every 1% of Health the enemy is missing.
Crimson Tide	Bleeding applied with Blades can stack 3 times.
Deathbolt	While wielding a Blade, defeating an enemy restores 20% Health and increases movement speed by 30% for 5 sec.

Monowires are considered as Blades so they will benefit from every perk in the Blades tree. Get Crimson Dance as soon as you can for the increased bleed chance then unlock Bloodlust so you can recover health when hitting Bleeding enemies. Unlock Deathbolt as well for the extra healing from defeating enemies.

Cold Blood (Cool)

Perk	Effect at Lv. 1
Merciless	While Cold Blood is active, increases Crit Chance by 5% and Crit Damage by 25%. +1% Crit Chance and +3% Crit Damage per Perk level.
Cold Blood	After defeating an enemy, gain Cold Blood for 7 sec. and increase movement speed by 2%. Stacks up to 1 time. The duration of each additional stack is 1 sec. shorter.
Will to Survive	Increases all Resistances by 3% per stack of Cold Blood.
Blood Brawl	While Cold Blood is active, increases damage with melee weapons by 5%.
Rapid Bloodflow	Increase Health regen inside and outside combat by 5% per stack of Cold Blood.
Defensive Clotting	Increases Armor by 4% per stack of Cold Blood.
Frozen Precision	Increases headshot damage by 5% per stack of Cold Blood.
Coolagulant	Stacks of Cold Blood are removed one by one, not all at once.
Predator	Increases attack speed by 10% per stack of Cold Blood.
Cold and Calculating	Landing a Crit Hit has 50% chance of applying a stack of Cold Blood.
Pain Is An Illusion	While Cold Blood is active, reduces damage taken by 5%.
Critical Condition	Increases duration of Cold Blood by 25%
Coldest Blood	Increases max stack amount for Cold Blood by 1.
Immunity	Grants immunity to Bleeding, Poison, Burn, and Shock when at least 4 stack(s) of Cold Blood are active.
Bloodswell	Upon receiving lethal damage while Cold Blood is active, prevents death, consumes all stacks of Cold Blood, restoring 10% Health per stack and grants Damage Immunity for 5 sec. Player cannot gain Cold Blood while perk is active. Cooldown 15 sec.

Most of the perks in this tree are activated with the Cold Blood perk, so get this first.

Bloodswell literally gives you an extra life with 15 seconds cooldown while Immunity lets you shrug off attacks with status effects, so these two are the most important perks to have after Cold Blood.

If you need to increase your survivability, unlock Will to Survive, Defensive Clotting, and Pain Is An Illusion. If you need more damage, get Frozen Precision, Blood Brawl, and Predator.

Ninjutsu (Cool)

Perk	Effect at Lv. 1
Crouching Tiger	Increases movement speed while sneaking by 20%.
Leg Up	Movement speed after a successful takedown is increased by 30% for 10 sec.
Strike From The Shadows	Increases your Crit Chance by 7% while sneaking.
Assassin	Deal 15% more damage to human enemies.
From The Shadows	Upon entering combat, Crit Chance increases by 10% for 7 sec.
Ghost	Detection time is increased by 20%.
Hasty Retreat	Temporarily boosts movement speed by 50% for 5 sec. when detected by an enemy.
Restorative Shadows	While in stealth, increases Health regen by 25%.
Cheat Death	When your Health drops below 50%, reduce all incoming damage by 50% for 10 sec. Cannot occur more than once per minute.
Jeepers Creepers	Crouch Attacks from stealth with melee weapons deal 100% more damage and guarantee a Crit Hit.

This tree is mostly for stealth plays so you can ignore most of these perks if you're into diving enemy groups the first chance you get.

The most important perks in this tree, regardless of your playstyle, are Assassin, From The Shadows, and Cheat Death.

Athletics (Body)

Perk	Effect at Lv. 1
Hard Motherfucker	When entering combat, Armor and Resistances increase by 10% for 10 sec. +1% per Perk level.
Regeneration	Health slowly regenerates during combat.
Pack Mule	Increases carrying capacity by 60.
True Grit	Increases max Stamina by 10%.
Epimorphosis	Increases Health regen threshold from 60% to 65% in combat and to 100% out of combat.
Wolverine	Health regen activates 20% faster during combat.
Steel And Chrome	Increases melee damage by 10%.
Invincible	Increases max Health by 15%.
Tenacious V	Getting hit does not interrupt Health regeneration.
Cardio Cure	Health regenerates 15% faster as you move.
Dog of War	Increases Health regen in combat by 30%.
Steel Shell	Increases Armor by 10%.
Indestructible	Reduces all incoming damage by 10%.

Your last perk points can be spent here for increased survivability, which will help you in mid-late game. Regeneration works well with the Rapid Bloodflow perk from the Cold Blood tree. If you need increased damage for your monowire, you can prioritize getting Steel and Chrome first before the rest of the perks related to Health and Armor.

Monowire Build Best Weapons

Overwatch

Effect	Increases reload speed. Comes with a custom silencer.

Take the Overwatch out when you're about to fight a horde of enemies and you want to bring down their numbers before charging in. This is particularly useful for popping heads that are on elevated or hard to reach platforms from a safe distance.

How to Get Overwatch

Fenrir

Effect	Deals thermal damage with increase chance to apply Burn. Reduced bullet spread and increased bullet impact, at the cost of high recoil.

Basically has the same purpose as the sniper rifle but for when you're already in the heat of the battle. SMGs like Fenrir can quickly take out enemies that your monowire can't reach. This iconic gun also has a chance to inflict Burn with its bullets!

How to Get Fenrir

Monowire Build Best Cyberwares

Operating System

QianT Sandevistan Mk.4

Cyberware	Effect (Legendary)
QianT Sandevistan MK.4	Slows time to 25% for 12 sec. Cooldown 15 sec. ・Increases any damage dealt by 15% when Sandevistan is active. ・Increases Crit Chance by 15% when Sandevistan is active.

There's a lot of things you can do while everything else is slowed down, especially with a melee weapon. Its increased damage and Crit Chance also allows your monowire to slice and dice through enemy lines.

What makes QianT Sandevistan Mk.4 better than other Sandies is its low cooldown, which can be further decreased with the Sandevistan: Heatsink mod and the Bioconductor cyberware.

Arms Cyberware

Monowire

Cyberware	Effect (Legendary)
Monowire	The Monowire charges when equipped but not used in combat. Attacks with a charged wire deal bonus damage based on the charge level. Charge level and bonus damage dealt decline with each attack. Three mod slots available (wire, battery, universal).

The bread and butter of this build. Monowires deal more damage the higher their charge level is so your first attack always hits the hardest. Their charge level goes back up quickly, though, and they can still dish out high amounts of damage even at low charge levels.

Other Cyberwares

Heal-on-Kill

Cyberware	Effect (Legendary)
Heal-on-Kill	Instantly restores 10% Health after defeating an enemy.

This cyberware allows you to recover health per kill, on top of the healing effects from Bloodlust and Deathbolt.

Biomonitor

Cyberware	Effect (Legendary)
Biomonitor	Instantly restores 100% Health when Health drops to 15%. Cooldown 120 sec.

If you can't outheal the damage you take, this cyberware gives you an emergency health recovery.

Second Heart

Cyberware	Effect (Legendary)
Second Heart	Instantly restores 100% of max Health when your Health falls to 0. Cooldown 2 min.

More healing! This cyberware brings you back to life upon taking lethal damage. If you have Bloodswell unlocked, it will take effect first before this cyberware.

Synaptic Signal Optimizer

Cyberware	Effect (Legendary)
Synaptic Signal Optimizer	Increases Health by 60%.

This increases your max health so you can survive in close combat for longer.

Bioconductor

Cyberware	Effect (Legendary)
Bioconductor	Reduces all cyberware cooldowns by 30%.

A cyberware that decreases the downtime of your other cyberwares, including the Sandevistan, so they can be used more frequently.

How to Play the Monowire Build

Activate Sandevistan and Slice Enemies

Playing with a monowire is simple: activate your Sandevistan, rush into the enemies, and start dicing them. It would also be better if you tag them first before charging in so you can maximize the cyberware's effect.

Before the slowed time ends, be sure to take cover especially if a sizeable number of enemies are targeting you. Rinse and repeat.

Keep Attacking Enemies to Recover Health

Further into the Blades tree are perks that will let you recover health by killing enemies or hitting enemies affected by Bleeding. A monowire with physical wires also has a chance to inflict Bleeding even without perks from the Blades tree.

With these perks, you can spam the attack button at enemies to apply the Bleeding effect and recover health while doing it to outheal the damage you're taking.

Take Cover If Needed

Enemies hit harder in late game and in high threat missions, especially in higher difficulties. If you need to, find cover and let your cyberwares go off cooldown before going back to the fight. Don't forget to also pop an inhaler if you're low on health!

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