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Diablo 4: Vessel of Hatred (D4)
The Serpentine Path Walkthrough and Where to Follow the Serpent
★ NEW: Season 10 Guide | Season 10 Release Date
┗ Seasonal Content: Chaos Rifts | New Uniques
┗ Seasonal Mechanic: List of Chaos Perks & Chaos Armor
★ Season 10 Best Builds & Best Chaos Perks
★ Check out our Vessel of Hatred expansion guide
The Serpentine Path is a Main Quest in Diablo 4 (Diablo IV). Learn how to follow the serpent, The Serpentine Path Map, all rewards, as well as completion tips!
The Serpentine Path Overview
Basic Information
| Quest Type | Main Quest | |
|---|---|---|
| Zone | Hawezar | |
| Starting Location | The Writhing Mire | Quest Giver | Lorath |
| Rewards | ||
| Renown | EXP | Gold |
How to Unlock The Serpentine Path
The Serpentine Path is started after you light the incense to complete the previous quest Judgement of the Swamp.
The Serpentine Path Quest Walkthrough
| Objective | |
|---|---|
| 1 | Follow Neyrelle Follow Neyrelle a bit north of the altar. She will stop by the giant serpent blocking the path. |
| 2 |  Speak with Neyrelle Interact with Neyrelle, who's just standing by the giant serpent. |
| 3 |  Follow the serpent with your allies After talking with Neyrelle, an area of the map encircled with a yellow circle will open up. Don't mind this, as it won't give you an indication of where to go. Instead, just follow the serpent's body up north. |
| Tip |  You will notice that following the serpent will lead you into a portion of the map that is hidden. Unfortunately, you will have to wait until after the quest to uncover the specifics of this area of the map. For now, you could refer to the above map guide. |
| 4 |  Survive the ambush Keep following the serpent's body until you reach a Healing Well. Here, you will be ambushed by enemies. Defeat them all, then Neyrelle will crawl under a small opening under the serpent. Survive another ambush after she crawls through. |
| 5 |  Reach Neyrelle After defeating all the enemies, head a bit east and Neyrelle will drop a ladder for you to climb onto a ledge. |
| 6 | Escape the Sinking Detritus Climb up the ladder and out to the area called Venom-Drenched Path to complete the quest. |
Dirge of the Mire Quest Walkthrough
The Serpentine Path Previous and Next Quests
| ◄Previous Quest | Next Quest► |
|---|---|
| Dirge of the Mire |
Diablo 4 Related Guides
Story Walkthrough and List of Main Quests
List of All Main Quests
| Prologue Quests | |
|---|---|
| Dusk on the Mountain | Darkness Within |
| A Hero’s Return | A Hero’s Reward |
| Prayers for Salvation | In Search of Answers |
| Rite of Passage | Missing Pieces |
| Act 1 Quests | |
| Ill Tidings | Tarnished Luster |
| The Knight and the Magpie | Undertaking |
| Below | In Her Wake |
| Storming the Gates | The Cost of Knowledge |
| Wayward | Shroud of the Horadrim |
| Fledgling Scholar | Light's Guidance |
| Kor Valar | Pilgrimage |
| Light's Judgement | Light's Protection |
| Crossing Over | Descent |
| Light's Resolve | - |
| Act 2 Quests | |
| An Unforeseen Visit | Dark Omens |
| Encroaching Shadows | Exhuming the Forgotten |
| Harrowed Lament | Apex of Misery |
| Parting Embers | Feral Nature |
| The Beast Within | The Path of Rage |
| Fangs of Corruption | Stemming the Flow |
| Buried Secrets | In Ruins |
| Entombed Legacy | Shadow Over Cerrigar |
| As the World Burns | - |
| Act 3 Quests | |
| The Spreading Darkness | Whittling Sanity |
| Suffering Disquiet | A Moment to Collect |
| Brought Low | The City of Blood and Dust |
| Small Blessings | Whispers from the Past |
| Through The Dark Glass | Descent Into Flame |
| Loose Threads | Oasis of Memories |
| Flesh from Bone | Beneath the Mask |
| Piercing the Veil | Exhumed Relics |
| Act 4 Quests | |
| Prying the Eye | A Master's Touch |
| Lost Arts | A Meeting of the Minds |
| Anguish Incarnate | Eye of the Storm |
| Act 5 Quests | |
| The Path Divided | Secrets of the Zakarum |
| Entombed Hatred | Swamp Hospitality |
| Witch of the Wastes | Encumbered Mind |
| The Cage of Grief | One Step Forward |
| Tainted Flesh | Wrack and Ruin |
| Cold Blood | Judgement of the Swamp |
| The Serpentine Path | Dirge of the Mire |
| The Slow, Beating Heart | A Cold and Lifeless Shore |
| Picking Through the Bones | Beneath the Wine-Dark Sea |
| Fragments of Mortality | On the Precipice |
| Knee-Deep in Filth | A Chorus of Voices |
| Act 6 Quests | |
| Evil Stirs in Kehjistan | The Jewel of the East |
| The Scouring of Caldeum | The Walls Shake |
| Turning the Tide | Essence of Hatred |
| In Desolation's Wake | Light Extinguished |
| The Blind Eye | What Lies Ahead |
| Epilogue Quests | |
| Promises | A Heavy Burden |
| Legacy of the Horadrim | - |
Campaign Guides
| Quest Guides | |
|---|---|
| Best Quest Order | How to Skip Campaign |
| Endgame Guide | Campaign Length |
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The Serpentine Path Walkthrough and Where to Follow the Serpent
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