Diablo 4: Vessel of Hatred Walkthrough & Guides Wiki

Diablo 4: Vessel of Hatred (D4)

Bitter Medicine Paragon Board Nodes

★ Check out our Vessel of Hatred expansion guide.
┗ Mercenaries | Kurast Undercity | Dark Citadel
★ Learn more about the Spiritborn class.
★ Conquer Nahantu with our best Builds!
★ Season 6 Guide (Season of Hatred Rising)
┗ Hatred Rising Event | Seething Opals

Bitter Medicine is a Spiritborn Paragon Board in Diablo 4: Vessel of Hatred. Read on to see an overview of this paragon board and a full breakdown of all its paragon nodes!

List of Contents

Bitter Medicine Paragon Nodes

Qty Rarity Node
4 Gate Board Attachment Gate
+5 Strength; +5 Intelligence; +5 Willpower; +5 Dexterity
1 Legendary Bitter Medicine
When you Heal for 100% of your Maximum Life, deal 395 damage to Close enemies. This damage is increased by your Healing Received bonus.
3 Magic +2% Maximum Life
3 Magic +12% Damage to Close Enemies
2 Magic +7 Strength
2 Magic +7 Intelligence
3 Magic +5% Poison Resistance
2 Magic +1% Maximum Poison Resistance
2 Magic +5% Fire Resistance
5 Magic +3% Healing Received
6 Magic +10% Damage
3 Magic +2.5% Attack Speed
24 Normal +5 Strength
9 Normal +5 Willpower
53 Normal +5 Dexterity
27 Normal +5 Intelligence
1 Rare Gifted
+20% Damage; +10 Dexterity
1 Rare Ambush
+24% Damage to Close Enemies; +10 Dexterity
1 Rare Poison Resistance
+2% Maximum Poison Resistance; +10% Poison Resistance
1 Rare Restorative
+6% Healing Received; 4% Maximum Life
1 Rare Natural Vitality
+6% Healing Received; +10% Fire Resistance
1 Rare Flash Fire
+20% Damage; +2.5% Attack Speed
1 Socket Glyph Socket
Place a Glyph to add an effect.

Builds That Use Bitter Medicine

Come back soon for more updates!

Diablo 4 Related Guides

Diablo 4 - Paragon.png

Paragon System Explained

Paragon Board Guides

Paragon Board Guides
All Paragon Boards by Class
Glyph Guides
All Glyphs Per Class Best Glyphs to Upgrade

All Paragon Boards by Class

Barbarian Paragon Boards
Starting Board Hemorrhage Blood Rage
Carnage Decimator Bone Breaker
Flawless Technique Warbringer Weapons Master
Force of Nature
Rogue Paragon Boards
Starting Board Eldritch Bounty Tricks of the Trade
Cheap Shot Deadly Ambush Leyrana's Instinct
No Witnesses Exploit Weakness Cunning Stratagem
Danse Macabre
Sorcerer Paragon Boards
Starting Board Searing Heat Frigid Fate
Static Surge Elemental Summoner Burning Instinct
Icefall Ceaseless Conduit Enchantment Master
Fundamental Release
Druid Paragon Boards
Starting Board Thunderstruck Earthen Devastation
Survival Instincts Lust for Carnage Heightened Malice
Inner Beast Constricting Tendrils Ancestral Guidance
Untamed
Necromancer Paragon Boards
Starting Board Cult Leader Hulking Monstrosity
Flesh-eater Scent of Death Bone Graft
Blood Begets Blood Bloodbath Wither
Fraility
Spiritborn Paragon Boards
Starting Board In-Fighter Spiney Skin
Viscous Shield Bitter Medicine Revealing
Drive Convergence Sapping

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