Diablo 4 (D4)

Infection Effect and How to Get

Infection is a Minor Vampiric Power introduced in the Season 2 (Season of Blood) update in Diablo 4 (D4). Read on to learn more about the effects of Infection, its Pact requirements, and how to get it!

Infection Overview

Diablo 4 (D4) - InfectionInfection Pact Requirements
Diablo 4 (D4) - Pact of FerocityFerocity Diablo 4 (D4) - Pact of DivinityDivinity Diablo 4 (D4) - Pact of EternityEternity
1 0 0
Effects
Hitting enemies with direct damage infects them with Pox. Inflicting Pox 8 times on an enemy expunges their infection, dealing 70% Poison damage.

All values under the Vampiric Power effect shown above are upgraded to their Maximum Level (Level 3).

All Vampiric Powers and How to Use

How to Get Infection

Unlock With Potent Blood

Infection can be randomly unlocked by spending 25 Potent Blood in the Seasonal tab in your character's inventory.

How to Farm Potent Blood

List of Builds with Infection

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Diablo 4 Related Guides

Diablo 4 - Vampiric Powers
All Vampiric Powers and How to Use

All Vampiric Powers

List of Major Vampiric Powers
Accursed Touch Bathe in Blood
Blood Boil Call Familiar
Flowing Veins Metamorphosis
Moonrise -
List of All Minor Vampiric Powers
Anticipation Coven’s Fangs
Domination Feed the Coven
Hectic Hemomancy
Infection Jagged Spikes
Prey on the Weak Rampart
Ravenous Resilience
Sanguine Brace Terror
Undying -

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