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Diablo 4: Vessel of Hatred (D4)

Efficacy Glyph Effects and How to Get

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This is a guide to Efficacy, a glyph in Diablo 4 (D4). Read on to see a list of Efficacy's effects and upgrades, as well as learn how to get Efficacy.

List of Contents

Efficacy Glyph Effects and Upgrades

Efficacy Rogue Glyph Effects

Efficacy ImageEfficacy Effect: Grants +[XX]% bonus to all Rare nodes within range.
Additional Bonus: Imbuement Skill effects have 20% increased potency.
Stat Requirement: 25 Intelligence
Legendary Bonus: Increase Non-Physical damage by 10.0%.
Level Requirement: Glyph Level 46

Glyph Upgrades

Level Radius Glyph Multipliers
1 3 Effect (XX%): 25
15 4 Effect: (XX%): 60.0
46 5 Effect (XX%): 137.5
Legendary (YY%): 10
100 5 Effect (XX%): 270.0
Legendary (YY%): TBD

How to Get Efficacy

Random Drop After Reaching Level 60

Upon reaching level 60, all Glyphs have a random chance to drop from enemies found throughout Sanctuary. We recommend taking on activities such as Helltides, Nightmare Dungeons, Tree of Whisper, and The Pit to have a higher chance of obtaining Glyphs.

Diablo 4 Related Guides

Diablo 4 - Paragon.png

Paragon System Explained

Paragon Board Guides

Paragon Board Guides
All Paragon Boards by Class
Glyph Guides
All Glyphs Per Class Best Glyphs to Upgrade

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