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Diablo 4: Vessel of Hatred (D4)

Ambidextrous Glyph Effects and How to Get

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This is a guide to Ambidextrous, a glyph in Diablo 4 (D4). Read on to see a list of Ambidextrous's effects and upgrades, as well as learn how to get Ambidextrous.

List of Contents

Ambidextrous Glyph Effects and Upgrades

Ambidextrous Barbarian Glyph Effects

Ambidextrous ImageAmbidextrous Effect: Grants +[XX]% bonus to all Magic nodes within range.
Additional Bonus: You deal 8% increased damage while wielding One-Handed weapons.
Stat Requirement: 40 Strength
Legendary Bonus: Increase Damage by 10.0%.
Level Requirement: Glyph Level 46

Glyph Upgrades

Level Radius Glyph Multipliers
1 3 Effect (XX%): 25
15 4 Effect: (XX%): 60.0
46 5 Effect (XX%): 137.5
Legendary (YY%): 10
100 5 Effect (XX%): 270.0
Legendary (YY%): TBD

How to Get Ambidextrous

Random Drop After Reaching Level 60

Upon reaching level 60, all Glyphs have a random chance to drop from enemies found throughout Sanctuary. We recommend taking on activities such as Helltides, Nightmare Dungeons, Tree of Whisper, and The Pit to have a higher chance of obtaining Glyphs.

Diablo 4 Related Guides

Diablo 4 - Paragon.png

Paragon System Explained

Paragon Board Guides

Paragon Board Guides
All Paragon Boards by Class
Glyph Guides
All Glyphs Per Class Best Glyphs to Upgrade

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