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Neo is a Rare Ritual rune in Diablo 4: Vessel of Hatred (D4). Read on to learn more about the Neo Rune, including the rune's conditions and how to get!
List of Contents
| Rune Basic Info | ||
|---|---|---|
 Neo |
Type | Ritual |
| Offerings | 200 | |
| Rarity | Rare | |
| Condition: Deal damage after not taking any within 5 seconds. (Resets if Invulnerable.) | ||
| Jump to a Section |
|---|
|
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Neo can randomly be obtained from chests and other activities in the game but we recommend doing activities with high Elite mob density such as The Pit, Nightmare Dungeons, or Kurast Undercity.
Crafting three runes of the same type will produce a random rune, allowing you a chance at obtaining Neo. You can craft runes at the Jeweler.
You can also get Neo by trading with other players. Since the other player will need to select which items to trade, you can use the in-game chat to coordinate which rune or item you wish to trade.
How to Trade
Similar to other runes in the game, Neo can only be obtained if you own the Vessel of Hatred Expansion. Players that have the base game and don't own the expansion may purchase it separately to access runes.
| Best Runeword Combinations | Best Ways to Farm Runes |
| All Ritual Runes | |||
|---|---|---|---|
| Yul | Cir | Ahu | Neo |
| Tam | Xol | Zan | Feo |
| Noc | Cem | Bac | Ur |
| Yax | Poc | Moni | Kaa |
| Lith | |||
| All Invocation Runes | |||
| Lac | Ohm | Vex | Gar |
| Xan | Que | Yom | Eom |
| Lum | Qua | Xal | Wat |
| Teb | Qax | Zec | Ner |
| Mot | Jah | Thul | Tzic |
| Kry | Ono | Tec | Met |
| Tun | Ton | Tal | Ceh |
Neo Rune Condition and How to Get
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