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Diablo 4: Vessel of Hatred (D4)

Lost Cause Quest Walkthrough

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★ NEW: Season 10 Guide | Season 10 Release Date
┗ Seasonal Content: Chaos Rifts | New Uniques
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★ Season 10 Best Builds & Best Chaos Perks
★ Check out our Vessel of Hatred expansion guide

Diablo 4 - Lost Cause

Lost Cause is a side quest in Diablo 4 (Diablo IV). Read on to learn how to unlock Lost Cause, a list of quest objectives, rewards, as well as a complete walkthrough.

List of Contents

Lost Cause Overview

Basic Information

Quest Type Side Quest
Zone Hawezar
Starting Location Vyeresz
Quest Giver Erdener
Rewards
Renown EXP Gold
Salvage Cache

Lost Cause Location

Lost Cause Walkthrough

Objective
1
Diablo 4 Lost Cause - Cultist Location
Collect Zakarum Prayer Amulets from Cultists
You need to defeat the cultists in the Reach of Adulation, as they drop the Zakarum Prayer Amulets. They're all found within the blue search region.
1a
Diablo 4 Lost Cause - Zakarum Prayer Amulet
Defeat all the enemies marked as red dots on the map for a chance to encounter a drop of the prayer amulets.
2
Diablo 4 Lost Cause - Erdener
Return to Erdener
Head back to Erdener in Vyresz, then speak to him to complete the quest.

Diablo IV Related Guides

Diablo 4 - Side Quests
List of Side Quests

List of Side Quests by Region

Diablo 4 Region Side Quests
Fractured Peaks Scosglen Dry Steppes
Hawezar Kehjistan Nahantu

Side Quest Related Guides

Hawezar Side Quests

Side Quests
The Heretic The Swamp's Protection
Traveler's Superstition Brought to Heel
Remnants of Faith Desperate Remedies
Fungal Remedies Gift of the Swamp
Lost Cause Tangled Memories
Ire of the Witch Necrotic Research
Bad Blood Hungering Necrolyte's Cache
Chained Zakarum Repository A Price to Pay
Poisoned Hearts Coiled Grasp
To Walk a Dark Path At Any Cost
Turbulent Waters By Three They Come
Flesh and Blood Venom of the Nangari
One Little Red Sprig Timeworn Effigy
A Debt Repaid Dead in the Water
The Greater Good Discretionary Spending
Bait the Trap Dead to Rights
Growing Reminders Unearthed Regrets
Perceived Threat Song of Rot
Heart of Mold What Can't Be Cured
A Question of Self Past Regrets
A Series of Steps Closing the Book
Glittering Abundance Lost Legacy
Left Behind Overstepping the Mark
Heart's Burden Drink to the Past
Good Riddance

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