This is a walkthrough for Separate Ways - Chapter 5 of Resident Evil 4 Remake (RE4). Read on for a detailed walkthrough, route maps for each objective, a list of important items obtainable, and tips on how to complete this chapter!

Separate Ways - Chapter 5 Basic Information

Chapter Summary

Reunite with Luis, only to find out that Krauser has stolen the Amber. You then group up with Leon as you follow Krauser onto the island.

Chapter Details

Enemies Encountered

Cultist (Zealot)	Garrador	Novistador
Pesanta

List of All Enemies

Separate Ways - Chapter 5 Walkthrough

Chapter Objectives

Use Iris to Track Luis

Follow Luis's footprints and look for his note to get out of the castle tower and head to the Gregorio's Waterway. In this section, you will encounter some cultists along the way. Use your handgun and melee attacks to clear a path while conserving ammo.

Go through the Waterway

Route Map

Throughout your exploration in the Waterway, you will find signs that Luis left for you to catch up to him. Continue to follow these signs until you are able to reach the Blast Furnace area.

Follow Luis's Signs

Go straight ahead until you reach an area where Ada will refuse to jump down into the water. Turn right, and you will find a small crevice that you need to pass through. After that, you will see the Lord of the Waterway Request. Pick it up and continue following the path to your right.

Drain the Water

From here, you will yourself in a small room where you can see a valve that you need to turn to drain the water, along with a Biosensor Scope. Turn the valve and pick up the scope before turning around to see the merchant.

Jump down into the water and look for the Lord of the Waterway (Large Fish) inside the cave. After that, you can continue to follow the path until you reach the Garrador.

Garrador Fight

Upon leaving the waterway, you will encounter a Garrador, along with some cultists who are blocking the elevator leading to the Blast Furnace. Stay low and eliminate all the cultists in the area before dealing with the Garrador. It is advisable to use your Blast Crossbow to kill the Garrador since it makes no sound when used.

Alternatively, if you don't have any Arrows for your Blast Crossbow, you can use your rifle with the Biosensor Scope to shoot the plaga behind the Garrador. This makes a lot of noise, make sure to reposition yourself after firing each shot.

How to Beat Garrador

Defeat Pesanta

Route Map

Upon reaching the Blast Furnace area, the Black Robe will immediately attack you, forcing you to jump down to the platform below. Using your Grappling Hook, Ada will pull the broken bridge to pin down the Black Robe, revealing the Pesanta.

Phase 1

Immediately pick up all the items and ammo behind you because you won't be able to return to this area after defeating the Pesanta. Once you've collected all the items, start focusing on its head and shoot it with your TMP or Rifle.

The area is spacious enough for you to kite the Pesanta without getting too close. Keep circling around the area while dealing damage with your powerful weapons. However, make sure to save your Arrows and Grenades for the second phase.

Phase 2

After dealing enough damage to the Pesanta, its tail will detach from the main body, triggering Phase 2 of the boss fight. You will now be in an area much larger than in Phase 1. Use this to your advantage and maintain your distance. Additionally, the Pesanta will sometimes spawn bombs on the floor that explode on contact. Try to move away from these bombs as much as possible.

Continue to keep your distance while waiting for the tail to become upright. Once it is still, look for the glowing wound on its chest and use your Blast Crossbow or Rifle to shoot it. Keep repeating this cycle until you defeat it.

How to Beat Pesanta

Go After Krauser

Route Map

After defeating the Pesanta and locating Luis, you will encounter Krauser as he attempts to escape the Castle with the Amber. Chase Krauser to the Clock Tower and then proceed inside the cave.

Open the Clocktower Gate

Go to the upper platform next to the Clock Tower and turn the valve to open the gate. Cultists will start spawning as soon as you turn the valve, and the gate will slowly begin to close. Try to eliminate all of the enemies in the area first before fully opening the gate, and then immediately run inside. Alternatively, you can use your Grappling Hook to take a shortcut after jumping down from the platform.

Blocked Path Inside the Cave

While inside the cave, you will encounter areas blocked by large rocks, preventing further progress. You need to locate a lever that will lift the rocks obstructing your path. Once you pull the lever, a path to the Ancient Chantry will open. These rocks will drop down for a few seconds before being lifted up again. Make sure that you time it when you cross to avoid getting crushed.

Boat Key at the Docks

Route Map

After using the elevator to reach the docks, you'll need to search for a boat key to group up with Leon and pursue Krauser to the Island.

Separate Ways - Chapter 5 Tips and Strategies

Separate Ways - Chapter 5 Tips and Strategies
Purchase the Ada Wong Charm Complete All the Requests

Purchase the Ada Wong Charm

This will enable you to rip shields away from cultists, rendering them vulnerable to your shots. It's an extremely useful ability, especially when you're surrounded by enemies with shields, allowing you to eliminate them much faster. You can exchange 5 Spinels for this Charm at the merchant.

How to Remove Shields with Grappling Gun

Complete All the Requests

In Chapter 5, there are two requests (Lord of the Waterway and Bug Buster) that you can complete to earn more spinels. It's advisable to finish them before proceeding to Chapter 6 because you won't be able to revisit previous chapters. You can exchange the Spinel rewards for valuable items such as treasures and charms.

Chapter 5 Completion Reward

Completing chapter 5 of the Separate Ways DLC rewards you with Adios, Don Quixote, and It Kept You Busy for a total of 800 CP. You can use these CP to purchase exclusive content from the Extras Shop.
Separate Ways Challenges

Resident Evil 4 Remake Related Guides

Separate Ways DLC Guide Hub

Separate Ways DLC Content

Separate Ways Story Walkthrough