Resident Evil 4 Remake (RE4) Walkthrough & Guides Wiki

Resident Evil 4 Remake (RE4)

Best Save Points on Professional

5

★ Separate Ways DLC Guide Hub
┗Walkthrough | Weapons | Requests | Unlockables
☆ Ada and Wesker have joined Mercenaries Mode!
★ VR Mode arrives in Winter 2023!
☆ Learn the best ways to speedrun & reach Professional S+!
★ Discover all the Skips you can make in a single playthrough!

Resident Evil 4 Remake - Best Save Points on Professional

In the Resident Evil 4 Remake (RE4), players are limited to 15 saves when aiming for an S+ Rank in Professional Mode. Check out the best save points you should use when playing on Professional!

List of Contents

Recommended Professional Save Points

When to Save in Professional Mode

Save # Story Section
1 After defeating Del Lago (Chapter 4)
2
RE4 Remake Best Professional Save Point #2
After retrieving Ashley from the Church (Chapter 5)
3
RE4 Remake Best Professional Save Point #3
Before the Chainsaw Sisters encounter (Chapter 6)
4
RE4 Remake Best Professional Save Point #4
Before the Mendez boss fight (Chapter 6)
5
RE4 Remake Best Professional Save Point #5
Before the Water Hall (Chapter 7)
6
RE4 Remake Best Professional Save Point #6
After the Armored El Gigante (Chapter 8)
7 After the Ashley segment in Chapter 9
(Start of Chapter 10)
8
RE4 Remake Best Professional Save Point #8
Before the Verdugo encounter (Chapter 10)
9
RE4 Remake Best Professional Save Point #9 Updated
Before the Minecart section (Chapter 11)
10 Before the first Krauser fight (Chapter 11)
11
RE4 Remake Best Professional Save Point #11
Before the Salazar fight (Chapter 12)
12 After the Regenerator section in Chapter 13
(Start of Chapter 14)
13
RE4 Remake Best Professional Save Point #13
Before the Transformed Krauser fight (Chapter 14)
14 End of Chapter 15
15
RE4 Remake Best Professional Save Point #15
Before the Saddler fight (Chapter 16)

Best Save Points on Professional

Professional Save Point Tips and Strategies
Check Icon Prioritize Saving Before Boss Fights
Check Icon Save Before Difficult Chapter Sections
Check Icon Save After Significant Weapon Upgrades
Check Icon Consider Saving at Points of No Return

Prioritize Saving Before Boss Fights

Resident Evil 4 Remake - Mendez Boss Fight Grab Attack

When going through Professional Mode, we recommend prioritizing using your saves right before boss encounters, especially if you're aiming for an S+ Rank. Since autosaves are disabled and boss fights are usually the most difficult sections of each chapter, it's best to save your progress at these points in the game.

List of All Bosses

Save Before Difficult Chapter Sections

Resident Evil 4 Remake - Chainsaw Sisters in Chapter 6

We also recommend saving before difficult chapter sections where you're likely to die or get a game over, such as the Chainsaw Sisters encounter in Chapter 6 and the Water Hall room in Chapter 7.

Save After Significant Weapon Upgrades

Resident Evil 4 Remake - Save After Significant Weapon Upgrades
You should also consider saving after significant weapon upgrades, such as getting your Exclusive Upgrades for the Chicago Sweeper and Primal Knife. Saving at these points in the game will let you retry sections while retaining every major power-up you've purchased and picked up.

Best Exclusive Weapon Upgrades

Consider Saving at Points of No Return

Resident Evil 4 Remake - Consider Saving at Points of No Return
If you're confident with the number of remaining saves you have, or if you're not aiming for S+ Rank and want to backtrack, you can also consider saving at points of no return, as they usually mark the beginning of a major section that could be difficult to get through.

List of Missables and Points of No Return

Resident Evil 4 Remake Related Guides

RE4 Remake Tips and Tricks

Tips and Tricks: A Beginner's Guide

All Tips and Tricks Guides

Unlockables
All Unlockables All Post Game Content
100% Completion Roadmap New Game Plus Guide
How to Get Infinite Ammo All Bonus Weapons
Professional Mode All Exclusive Upgrades
Extra Content Shop Locked Drawer
Expanded Treasure Map How to Claim Bonus Content
Mad Chainsaw Mode (Demo) -
Speedrun Guides
How to Get S+ Rank Professional S+ Guide
Best Save Points on Professional How to Skip First Village Fight
How to Skip Gallery Bridge How to Skip Wrecking Ball Wall
How to Skip the Dynamite How to Skip the Sun and Moon Switches
How to Raise Cannon Eariler How to Speed Through Ashley Library Section
How to Skip the Farm: Get Wooden Cog Fast Speedrun Guide
How to Skip Automatic Turret Lasers How to Skip AA Turret
Mercenaries Guides
Mercenaries Rewards Mercenaries Characters Tier List
Best Character for Each Stage How to Use Mayhem Mode
How to Increase Time Limit How to Increase Bonus Rate
Does Mercenaries Have Aim Assist? Best Mercenaries Abilities
Weapon Guides
Best Weapons Best Equipment for Professional Mode
Best Loadout Strongest Guns
Best Exclusive Weapon Upgrades Best Weapons to Upgrade
How to Upgrade Weapons Best Handgun and Pistol
Best Shotgun Best SMG
Best Rifle Best Magnum
Best Knife Knife Durability
How to Repair Knives Best Weapons to Get First
Trophy and Challenge Guides
Achievements List and Trophy Guide List of Challenges
Astute Appraiser Frugalist
Silent Stranger Sprinter
Minimalist Eat This!
Real Deadeye Smooth Escape
Hope You Like Thrill Rides! Too Cool For Such Tricks
Capacity Compliance CP Farming Guide
Settings Guides
Aiming Guide Best Settings for Consoles
Best Settings for PC Best Controls for Console
Best Quality-of-Life Settings Frame Rate or Resolution Priority
How to Turn On Subtitles How to Change Language Settings
Where to Adjust Brightness Settings -
Combat Guides
How to Save Ammo How to Dodge and Avoid Attacks
How to Parry Attacks How to Stealth Kill Enemies
How Do Critical Hits Work What to Do When You Have No Ammo
How to Do a Suplex How to Swap Guns
What Does the Plus 1 Mean? How to Get Assault Rifle Ammo
How to Repair Body Armor Knife Only Tips and Strategies
Money and Merchant Guides
All Merchant Locations Money Farming Guide
What to Buy First What to Sell First
How to Farm Spinels What to Trade Spinels For
Limited Time Sale Guide How to Get Gemstones
Trading Guide How to Get Exclusive Upgrade Tickets
Charms Guides
Best Charms to Equip Can You Reroll the Charm Gacha?
Shooting Range Guide -
Inventory Guides
How to Manage Inventory How to Rotate Items
How to Increase Attache Case Storage What to Do With Excess Items
Crafting Guide All Crafting Recipe Locations
Why Can’t I Store Items? -
Survival Guides
How to Increase Health How to Disarm Traps
How to Disarm Tripwires How to Quick Turn
How to Climb Walls and Ledges All Yellow Herb Locations
FAQs
Difficulty Differences Missables and Points of No Return
List of Exploits All Bugs
How to Save How to Change Costumes
Can You Turn on the Flashlight? Can You Throw Back the Dynamite?
Can You Kill the Merchant? Should You Register a Capcom ID?
Is There Transmog? How to Get Infinite Knife Durability
Can You Kill Saddler Without the Rocket Launcher? How to Change FOV
Story Guides
Ending Explained Post-Credits Scene Explained
How to Get the Wrench How to Get Past the Village
How to Get Back to the Church How to Get to Ashley in the Castle
Should You Save or Kill the Trapped Dog? What Happened to the Dog?
How to Get to the Forest Altar Where's Everyone Going? Bingo? Meaning
Should You Climb the Bell Tower? How to Use the Boat
How to Use the Cannon Minecart Guide
Clocktower Lift Guide -

Comment

See more comments (5 Comments)

Author

Resident Evil 4 Remake (RE4) Walkthrough Team
This article was created by Game8's elite team of writers and gamers.

    Walkthrough Menu

    Separate Ways DLC

    Separate Ways Walkthrough

    Separate Ways Puzzles

    Separate Ways Bosses

    Separate Ways Tips and Tricks

    Mercenaries Mode

    Mercenaries Guides

    Mercenaries Characters

    Mercenaries Stages

    Mercenaries Weapons

    Mercenaries S++ Guides

    Story Walkthrough

    Requests

    Puzzles

    Secrets

    Interactive Map

    Tips and Tricks

    Unlockables

    Speedrun Guides

    Weapon Guides

    Trophy and Challenge Guides

    Settings Guides

    Combat Guides

    Merchant and Money Guides

    Charms and Cases Guides

    Inventory Guides

    Survival Guides

    FAQs

    Story Guides

    Collectibles

    Keys and Locks

    Weapons

    Items

    Bosses

    Enemies and Monsters

    Characters

    Main Characters

    Villains

    Supporting Characters

    Non-Returning Characters

    News and Game Info

    Other Resident Evil Wikis

    Game8 JP Wiki

    Rankings

    Popular Articles
    Message Board
    • We could not find the message board you were looking for.

    Gaming News

    Stellar Blade’s Skin Suit Makes It Harder

    Stellar Blade’s Skin Suit Makes It Harder

    Popular Games

    Recommended Games

    All rights reserved

    ©CAPCOM CO., LTD. ALL RIGHTS RESERVED.

    The copyrights of videos of games used in our content and other intellectual property rights belong to the provider of the game.
    The contents we provide on this site were created personally by members of the Game8 editorial department.
    We refuse the right to reuse or repost content taken without our permission such as data or images to other sites.