This is a walkthrough for Chapter 13 of Resident Evil 4 Remake (RE4). Read on for a detailed walkthrough, route maps for each objective, a list of important items obtainable, and tips on how to complete this chapter!

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Chapter 12	Chapter 14

Chapter 13 Basic Information

Chapter Summary

Ashley was taken by Krauser to an island far from the castle. Leon has to find a way to get to Ashley's holding cell and deliver the medicine in time.

Chapter Details

Chapter 13
Location	Island
Recommended Weapons	TMP Striker Stingray

Enemies Encountered

Ganados (Villagers)

Regenerators

List of All Enemies

Chapter 13 Walkthrough

Chapter Objectives

	Objectives
1	Go after Ashley
2	Rescue Ashley
3	Get the Level 3 Keycard

Go After Ashley

Route Map

Sneak Past the Turrets

Follow the path ahead to the tunnels until you reach a turret. A bit further from here, you will find a small opening to your left which you can use to reach the back of the turret and make it face the wall.

Now that it's safe to pass, cross to the next area where you can find your first kills on this new area. There are also turrets here that you can use to redirect the enemies as even they won't dare to pass through the scanners.

Climb to the turret on the right and make it switch directions. Drop down and go around the first turret you came across and do the same.

Head towards the last turret on the other side and interact with it so its scanners aren't aimed at the doors. Now return to where the second turret is to find a clear path towards the building.

Move to the Next Area

Cross the wooden bridges until you find a ladder. Climb up to the next area with more enemies. Turn right towards the direction of the next building that you need to get to then follow the path up ahead.

You might want to snipe down the enemy holding a Rocket Launcher first then the crossbows before rushing in.

Open the Door in the Surveillance Room

Pass through the double doors and follow the path down. Turn left on the fork then left again up the stairs. The door at the end is booby trapped so disarm it first before entering the Surveillance room.

Climb the ladder on your left, turn left again, and follow the path to another room where you can unlock the marked door below.

Head downstairs through the newly unlocked door and you'll spot Ashley down the room below.

Rescue Ashley

Route Map

Find a Way to Unlock the Holding Cell

Drop down the ledge and look on your left to find two enemies guarding Ashley's room. Climb the ladder across and enter the room to your right. Move through the rooms and keep following the path until you end up at the next merchant.

Enter the next room from the merchant and turn left to the other end of the hallway. Turn right again and enter the Dissection area. Head for the southeast room to find the Laboratory Notice file and your next objective.

Get the Level 3 Keycard

Route Map

Find the Level 1 Keycard

Pull the lever next to you to reroute the power to the Dissection area. Leave the room and pull the lever next to the gate to open a shortcut between the Dissection area and the hallway in the middle.

Run all the way north (still in the same area) to find a console where you need to solve a calibration puzzle to complete. Enter the room and grab the Level 1 Keycard at the back.

Solution
Map	Location
Chapter 13	Dissection Room

Electronic Lock Puzzle Solutions

The Regeneradors will now come at you.

Increase the Keycard Clearance

Go back to the southeast room and reroute the power back to the Freezer area. Run to the Freezer area and unlock it using the keycard. Interact with the terminal at the back of the room to start overwriting your keycard with level 2 clearance. This awakens another Regenerador.

Get the Biosensor Scope

Now go back to the central hallway and run all the way south to the locked door (near the merchant room). Open it with the keycard and go down to the lower level.

Enter the Incubation Lab and check the small room north to find the Biosensor Scope, an attachment for your rifle that lets you see the plagas inside the Regeneradors.

Get the Wrench

Use the Biosensor Scope to look at all of the Regeneradors in the incubators and see which one has absorbed the Wrench key item into its body. Kill that Regenerador by shooting both of the glowing parasites inside its body. After it's dead, pick up the Wrench and use it to open the terminal in the small room that increases your clearance to level 3. Survive the wave of enemies while it's being overwritten.

How to Get the Wrench

Return to Ashley

With the Level 3 Keycard in hand, take the shortcut west of the Incubation Lab and return to the Holding Cell where Ashley is to complete the chapter.

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Chapter 12	Chapter 14

Chapter 13 Tips and Strategies

Chapter 13 Tips and Strategies
Get the LE 5 in the Freezer Area Use shotguns against the Regeneradors in the meantime

Get the LE 5 in the Freezer Area

Solution
Map	Location
Chapter 13	Freezer

Electronic Lock Puzzle Solutions

After getting the Level 1 Keycard from the Dissection Area, you can redirect the power back to the freezer area to access another Electronic Lock. You will need the Level 1 Keycard from the first Electronic Lock to access this area.

Use Shotguns Against the Regeneradors in the Meantime

Regeneradors can be encountered before you get the Bioisensor Scope. In the meantime, you can use shotguns to expose the plagas inside the Regeneradors' body before shooting them with a more accurate weapon.

Some plagas are located at the target's back, so you might need to dismember their legs so they drop drown and expose their backs.

Chapter 13 Collectibles

Clockwork Castellan

Map Location	In-Game Location

You can find this Clockwork Castellan in the southeasternmost area from the Surveillance section on the map. Look for the green forklift and red truck and zoom in on the gap between them to find the Castellan on the floor.

All Clockwork Castellans Locations

Yellow Herb

Map Location	In-Game Location

A Yellow Herb can be found in Chapter 13 in the caves of the Wharf. A second Yellow Herb can be found in the same chapter under the stairs in the Incubation Lab.

All Yellow Herb Locations

Treasures

Pearl Bangle

Map Location	In-Game Location

The Pearl Bangle can be obtained from a treasure chest on the ground by moving the turret on the left.

Golden Lynx

Map Location	In-Game Location

The Golden Lynx can be obtained behind the large door in the wharf on the second floor to the southeast cave. Shoot the explosive barrel to destroy the walls.

Elegant Crown

Map Location	In-Game Location

The Elegant Crown can be obtained from a treasure chest after defeating an enemy wielding a rocket launcher guarding a closed gate.

Velvet Blue

Map Location	In-Game Location

The Velvet Blue can be obtained from an attache case in the Surveillance room.

Velvet Blue

Map Location	In-Game Location

Another Velvet Blue can be obtained from an attache case in the Utilities room.

Red Beryl

Map Location	In-Game Location

The Red Beryl can be obtained by breaking the glass in the small room on the left side of the Dissection room.

Gold Ingot

Map Location	In-Game Location

The Gold Ingot can be obtained by breaking the glass in the opposite room to the west of the Dissection room.

Biosensor Scope

Map Location	In-Game Location

The Biosensor Scope can be found in a small room at the back of the Incubation Lab.

All Island Treasures

Hidden Treasures

Note: Hidden Treasures only appear with the Expanded Treasure Map from the Deluxe Edition.

Emerald

Map Location	In-Game Location

The Emerald can be obtained after defeating an enemy wielding a rocket launcher at the wharf guarding the gate. Shoot down the basket hanging above the gate.

Spinel

Map Location	In-Game Location

The Spinel can be obtained by shooting down the container hanging from the ceiling in the Merchant's room.

Silver Token

Map Location	In-Game Location

The Silver Token can be obtained by shooting down the container suspended from the ceiling at the bottom of the stairs leading down from Dissection to the Incubation Lab.

All Island Hidden Treasures

Resident Evil 4 Remake Related Guides

Story Walkthrough: All Chapters

Village Chapters

All Village Chapters
Chainsaw Demo	Chapter 1
Chapter 2	Chapter 3
Chapter 4	Chapter 5
Chapter 6	-

Castle Chapters

All Castle Chapters
Chapter 7	Chapter 8
Chapter 9	Chapter 10
Chapter 11	Chapter 12

Island Chapters

All Island Chapters
Chapter 13	Chapter 14
Chapter 15	Chapter 16