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U-3 is the missing boss in the Resident Evil 4 Remake's (RE4) main story. Read on to learn where the U-3 could potentially show up in the future!
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Unfortunately, U-3 does not appear in the remake's main story, and players won't be able to fight it. In the original, the U-3 was a Boss-type enemy, which Leon encountered in the Island.
Story Walkthrough: All Chapters
Although U-3 won't appear in the story, it was still mentioned in the Chronicles of Pursuit 2 file you can find in the Castle Throne Room.
The file is a journal written by Isidro Uriarte Talavera, a servant of Ramon Salazar. In it, they write about their process creating the U-3 ("U-III") by fusing the DNA of an insect with that of his human housekeeper.
The current status of the U-3 is unknown by the game's ending.
There's stlll a chance that U-3 will appear as an enemy in the Mercenaries Mode of the game, considering the difficulty of this game mode. Mercenaries Mode will release on April 7, 2023 as a free DLC for all the players who buy any of the Game Editions.
 Del Lago |
 El Gigante |
 Chainsaw Sisters |
 Mendez |
 Armored El Gigante |
 Verdugo |
 Dos Gigantes |
 Krauser |
 Salazar |
 Krauser (Transformed) |
 Saddler |
- |
Where is the U-3? Missing Boss Fight
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