How to Beat Biological Intel: Breath of Life

This is a guide on how to beat Biological Intel: Breath of Life in the Combat Simulator of Final Fantasy 7 Rebirth (FF7 Rebirth). Check out the unlock requirements and rewards, a list of enemies and bosses in each round, and the best party, equipment, and Materia to beat this challenge.

Best Party and Builds

Best Party for Biological Intel: Breath of Life
Cloud	Aerith	Tifa

Cloud Equipment and Materia

Cloud Main DPS
		Weapon		Armor
		Sleek Saber		Sailor's Bracer
		Accessory		Summon Materia
		Talisman		Titan
Weapon Materia			Armor Materia
Ice HP Up MP Up			ATB Stagger Precision Defense Focus Steadfast Block
Weapon Skills
ATB Charge Rate Up			-
-			-

Cloud will be the Main DPS of this fight since he can quickly stagger enemies with Focused Thrust once they are pressured. You can also equip Ice materia to pressure the Quetzalcoatl easily.

Aerith Equipment and Materia

Aerith Support / Magic DPS
		Weapon		Armor
		Empress's Scepter		Gold Coral Armlet
		Accessory		Summon Materia
		Talisman		Shiva
Weapon Materia			Armor Materia
Fire and Ice Wind First Strike Spirit Up			Magnify + Healing MP Up HP Up
Weapon Skills
MP Recovery Rate Up			MP Limit
-			-

Aerith will be the Support and Magic DPS of the team due to her high magic-related stats. Make sure to always have an ATB charge saved up so you can be prepared to heal your party whenever needed.

Tifa Equipment and Materia

Tifa Sub DPS
		Weapon		Armor
		Sylph Gloves		Sailor's Bracer
		Accessory		Summon Materia
		Talisman		Ifrit
Weapon Materia			Armor Materia
Chakra Wind Precision Defense Focus			HP Up Auto-Unique Ability Provoke
Weapon Skills
Enhanced Techniques			-
-			-

Tifa will be the Sub DPS for this fight since she can deal high single-target damage with her abilities. She will also be crucial in pressuring and staggering the Archdragons without accidentally killing them.

How to Beat Biological Intel: Breath of Life

Biological Intel: Breath of Life Tips
Presure the Enemies by Exploiting Weaknesses
Stagger the Archdragons Carefully
Use Aerial and Magic Attacks When Enemies Fly
Move Away during Electrodiffusion

Pressure the Enemies by Exploiting Weaknesses

The Quetzalcoatl is weak to Ice attacks, while the Archdragons are weak to Wind attacks. Exploit these weaknesses with spells to pressure the enemies. Once they are pressured, you can use Cloud's Focused Thrust if they are on the ground to quickly stagger them.

Stagger the Archdragon Carefully

The Archdragons have low health, so you need to be careful not to accidentally kill them without staggering. You can switch to Tifa and charge her ATB gauge by locking onto Quetzalcoatl first. Then, you can use Aero on the Archdragons to pressure them, and follow it up with basic attacks to stagger.

Use Aerial and Magic Attacks When Enemies Fly

When the Quetzalcoatl starts flying, you can switch to Aerith to cast Ice spells or ranged basic attacks on it. You can also get Cloud and Tifa to perform aerial attacks when their ATB gauge is empty. Although, note that these characters can only use certain abilities while in the air.

How to Perform an Aerial Attack

Character	How to Aerial Attack
Cloud	・ Press then Hold after to launch into the air. ・ Use the Triple Slash or Firebolt Blade abilities to launch into the air.
Tifa	・ Unlock Leaping Strikes in Tifa's Folio ・ Use the Soaring Flurry or Heavenly Ascent Synergy Skills to launch Tifa into the air.

How to Attack Flying Enemies

Move Away during Electrodiffusion

At some point, Quetzalcoatl will use Electrodiffusion, dealing strong AOE lightning damage around itself. When it starts raining lightning attacks, make sure to move away and keep your distance to avoid this attack.

Biological Intel: Breath of Life Unlock and Rewards

Requirements and Rewards

Defeat Classified Intel: Grasslands Region

To unlock Biological Intel: Breath of Life in the Combat Simulator, you will first need to defeat Quetzalcoatl in the Classified Intel: Grasslands Region. You can unlock this intel after you have completed 4 of the 6 Expedition Intels in the Grasslands.

How to Beat Quetzalcoatl

Assess 10/10 Enemies in Junon

No.	Enemy	Where and How to Encounter
39	Sandstorm Drake	Can be encountered during the When Words Won't Do side quest at a crossroads.
62	Tonadu	Found guarding Activation Intel 3: Battery Hill Tower along with a Zemzelett.
63	Fonadu	Found in the Cacophonic Corvid Combat Assignment. Players must cmplete Activation Intel 2: Buffeted Cape Tower on Junon during Chapter 4.
65	Fleetwing	The Fleetwing can be located on the ruined houses by the fences
66	Stormwing	Found in the Weather the Storm Combat Assignment, found east of the Prospect Tower during Chapter 4.
87	Mystic Dragon	Can be encountered during the Dreaming of Blue Skies side quest at a narrow path.
90	White Mousse	Can be encountered during The Hardest Sell side quest at the southeastern part of the region.
94	Zemzelett	The Zemzelett can be located on an area between a crater and a cargo ship south of Gabe's Ranch
95	Whymzelett	Found in the Zemze Breaks Combat Assignment. Players must complete Activation Intel 3: Batteryhill Tower, then head east of the tower during Chapter 4.
96	Ignilisk	Ignilisk can be located on the road straight pass the Mythril Mine near the ruined houses
97	Lavalisk	Found in the Scorched Earth Combat Assignment. Players must first complete Activation Intel 4: Piedmont Tower, and then have a Mountain Chocobo for a mount to climb walls during Chapter 4 in Junon.
98	Capparwire	The Capperwire can be located south of the big factory near the Junon Checkpoint
100	Mindflayer	The Mindflayer can be encountered in the Classified Intel Report: The Whisperer in the Darkness. The intel will be unlocked once you've analyzed the Lifesprings in all of the Expedition Intel Report locations in the Junon Region.

Junon Region Interactive Map

Level Up Enemy Skill Materia to ★★

You will need a ★★ Enemy Skill Materia to do this combat sim. You can quickly level up the materia by linking an AP Up Materia with it. Then, defeat groups of enemies from other combat sim challenges or from Fiend Sightings.

AP Farming Guide

Final Fantasy 7 Rebirth Related Guides

All Combat Simulator Battles and Rewards

All Combat Simulator Articles

Biological Intel

Brutal Challenges

Legendary Bouts