Chem Resistant is an Endurance Perk in Fallout 4 (FO4). Learn if Chem Resistant is worth it, Chem Resistant's ID and ranks, as well as how to get and unlock Chem Resistant.

Is Chem Resistant Worth It?

Good For Players Always Using Chems

Chems or chemicals are consumable items that give different buffs in exchange for side effects when ingesting them. You can gain resistance or complete immunity to that side effect with the Chem Resistant perk.

If you don't plan on consuming them, it's best to save your points on other perks instead of getting Chem Resistant!

Best Perk Tier List

Chem Resistant Perk ID

All Chem Resistant IDs

List of All Perk IDs

Chem Resistant Ranks

How to Get Chem Resistant

Unlock Chem Resistant at Endurance 4

Chem Resistant is on Endurance Level 4

The Chem Resistant perk is unlocked when your Endurance is at Level 4. You can start at this level by assigning 4 points to Endurance during the Registration Form at the start of the game. Otherwise, you can get to this level by collecting SPECIAL magazines or bobbleheads and spending perk points upon level up.

After getting to Endurance 4, you're free to spend perk points on ranking up the skill, as long as you are at the required character level to rank up.

Fallout 4 Related Guides

Fallout 4 Perk Chart

All Perks Guide

All Endurance Perks

Toughness	Lead Belly	Life Giver
Chem Resistant	Aquaboy / Aquagirl	Rad Resistant
Adamantium Skeleton	Cannibal	Ghoulish
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