
Zyranium causes poisoning in The Outer Worlds 2. Read on to learn more about Zyranium, how to remove Zyranium poisoning, as well as a list of equipment with Zyranium effects.
List of Contents

To remove Zyranium poisoning, use an AutoDoc or visit any doctor and ask them to cure it for a fee. AutoDocs and doctors can commonly be found in towns across Arcadia, with one of each available in The Incognito.
| Zyranium Equipment | |
|---|---|
The Dose |
Zyranium Ray |
Zyraniator |
Zyranium Grenade |
The Dose |
|
| Type | Helmet |
|---|---|
The Dose is a Unique Helmet that grants +40% Toxicity Drain Rate. With The Poison mod, gain +20% Crit Chance while standing in Zyranium cloud and Zyranium poisoning is gained 50% slower.
Zyranium Ray |
|
| Type | Special |
|---|---|
The Zyranium Ray is a Unique Special weapon with the Zyranium-Powered mod, which poisons organic targets with Zyranium, causing them to take progressively more damage from this weapon.
Automechanicals, however, will take no damage and instead will become Overcharged, gaining speed and power.
Zyraniator |
|
| Type | Pistol |
|---|---|
The Zyraniator is a Unique Pistol with the Zyranium-Infused mod, which fires depleted Zyranium rounds that causes targets to take progressively more damage from this weapon.
This mod can also fire longer in Tactical Time Dilation. Automechanicals, however, will take no damage and instead will become Overcharged, gaining speed and power.
Zyranium Grenade |
|
| Type | Thrown Item |
|---|---|
Zyranium Grenade is a Thrown Item that leaves a cloud of Zyranium gas at its location, dealing damage to all humans and creatures within the area. Zyranium exposure can inflict Overcharge on automechanicals.
| Perk | Effect | Req. |
|---|---|---|
Zyranium Absorption |
・Zyranium poisoning is accumulated 50% slower ・-35 Zyranium poisoning on drug crash end |
・Medical 3 |
Zyranium Powered |
・Up to 10 energy per 1s as Zyranium poisoning increases | ・Requires 7 or more total perks purchased ・Perk: Zyranium Absorption ・Science 5 |
Zyranium is a dangerous hazard that's found throughout Arcadia, powering the Protectorate's automechs. Standing in Zyranium poisons you, lowering your maximum Toxicity. Too much Zyranium poisoning can prove fatal!
| Status | Effect |
|---|---|
| Reduces max health and causes you to cough loudly every so often. | |
| Reduces max health and causes you to cough loudly every so often. Effects are more severe than Light Zyranium Poisoning. | |
| Increases damage dealt and attack speed. Can only be applied to automechanicals when affected by Zyranium. |
Exposure to Zyranium inflicts Light Zyranium Poisoning, which reduces max health. Prolonged or heavier exposure will lead to Heavy Zyranium Poisoning, causing more severe effects.
Meanwhile, automechanicals exposed to Zyranium will be inflicted with Overcharged, increasing their damage and attack speed. With this, be careful when dealing with Zyranium near automech enemies.
Damage Types and Status Effects Explained

Beginner's Guide: Tips and Tricks
What Is Zyranium?



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