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Bosses are notable Stardust-afflicted aberrants you will face in Once Human. Read on for a list of all bosses and elite enemies, including their location, weaknesses, tips to beat them, and the rewards you can get after defeating them!
Lv. | Boss | Overview |
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10 |
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Location: Monolith of Greed Weaknesses: ・Slime Head Rewards: Melee Amplifier, Munitions Amplifier, Weapon Mod Parts, Stardust Source, Electronic Part Notable Tips: ・Focus on the Gatling Gun lodged in its arm first ・Destroy the Eggs it spawns ・Camp near indestructible walls to safely remove the shadows |
20 |
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Location: Gaia Cliff Monolith Weaknesses: ・Woman Body Rewards: Melee Amplifier, Munitions Amplifier, Weapon Mod Parts, Stardust Source, Electronic Part Notable Tips: ・Exterminate the extra enemies first ・Position yourself where you can see the humanoid before destroying the vines ・Hiding behind cover mitigates almost all the Treant's attacks |
30 |
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Location: Mirage Monolith Weaknesses: ・Pus-riddled Abdomen ・Head Rewards: Energy Link, Gear Mod x2, Weapon Mod Parts, Stardust Source, Electronic Part Notable Tips: ・Use Tactical Drone to increase visibility in smoke ・Focus on the little spiders for safety ・Use Fortress Warfare to avoid Poison Fog damage |
40 |
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Location: Monolith of Thirst Weaknesses: ・Head ・Shoulders Rewards: Energy Link, Gear Mod x2, Weapon Mod Parts, Stardust Source, Electronic Part Notable Tips: ・Kill the lesser dogs first ・Position far away so Rabizex uses easy-to-avoid attacks |
Boss | Overview |
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Location: Monolith of Greed Weaknesses: ・Head Rewards: Acid |
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Location: Hearst Industries Weaknesses: ・Back Rewards: Energy Link, Stardust Source, Acid, Eclipse Cortex Lv. 2 |
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Location: Eastern Railway Junction Weaknesses: TBD Rewards: Acid |
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Location: Rotten Saddle Weaknesses: ・Abdomen sac Rewards: Energy Link, Stardust Source, Acid, Eclipse Cortex Lv. 1 |
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Location: High Banks Weaknesses: ・Balloons Rewards: Energy Link, Stardust Source, Acid, Eclipse Cortex Lv. 1 Notable Tips: ・Attack the balloons that light up |
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Location: Hearst Industries Weaknesses: TBD Rewards: Acid |
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Location: Overlook Town Weaknesses: ・Legs ・Head Rewards: Energy Link, Acid, Eclipse Cortex Lv. 1 Notable Tips: ・Focus attacking the leg sores ・Attack the inside of the head when it falls to the ground |
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Location: Overlook Town Weaknesses: ・Head Rewards: Acid |
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Location: TBD Weaknesses: TBD Rewards: TBD |
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Location: Refinery Pollution Point Weaknesses: ・Woman body Rewards: Acid Notable Tips: ・Focus shooting the body behind the mirror ・Avoid shooting the mirror as the bullets get deflected directly at you |
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Location: Greenlake Hill Weaknesses: ・Head Rewards: TBD |
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Location: Sutherland Chemical Plant Weaknesses: ・Umbrella Rewards: Energy Link, Stardust Source, Acid, Eclipse Cortex Lv. 1 Notable Tips: ・Attack the top of the umbrella |
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Location: Junkyard Weaknesses: TBD Rewards: Energy Link, Gunpowder, Eclipse Cortex Lv. 2 Notable Tips: ・Use throwable items such as grenades or molotovs to deal damage behind the shield |
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Location: Gaia Research Center Ruins Weaknesses: ・Head Rewards: Energy Link, Weapon Mod Parts, Rosetta V2 Access Card, Gunpowder, Eclipse Cortex Lv. 1 |
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Location: Junkyard Weaknesses: ・Head Rewards: Energy Link, Rosetta V2 Access Card, Gunpowder, Eclipse Cortex Lv. 2 Notable Tips: ・Shoot the drone on the back |
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Location: Gaia Research Center Ruins Weaknesses: ・Head Rewards: Acid |
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Location: Holt Town Weaknesses: ・Traffic lights Rewards: Energy Link, Stardust Source, Acid, Eclipse Cortex Lv. 1 Notable Tips: ・Shoot the traffic lights ・Fight from a distance |
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Location: Rotten Saddle Weaknesses: TBD Rewards: Acid |
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Location: Greenlake Hill Weaknesses: ・Head ・Back Rewards: Energy Link, Acid, Eclipse Cortex Lv. 1 |
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Location: Eastern Railway Junction Weaknesses: ・Head Rewards: Acid |
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Location: Brookham Weaknesses: ・Head Rewards: Acid Notable Tips: ・Shoot the light in the head |
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Location: Blackfell Fallen Zone Weaknesses: ・Lit Television Head Rewards: Energy Link, Artisan's Touch, Acid, Eclipse Cortex Lv. 1 Notable Tips: ・Focus attacking the lit television head ・Move around the area to avoid it attacks |
Boss Tips |
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Depending on the difficulty of the boss, there is a specific number of players that the game recommends to join. In most cases, it is wise to follow the game's advice since some bosses can be brutal without proper preparation!
Consumables are crucial not only for your survival with healing but also allow you to stack buffs so you can deal more damage to bosses!
Each unique Deviant serves a different purpose, some designed better for combat! Look to bring a Deviant that aids you at specific phases of a boss.
Deviants Guide: All Deviant Locations
While your current build could be strong, some loadouts are better for specific bosses you face. For example, the Ravenous Hunter uses linear attacks with its Gatling Gun, so it is best to snipe it out while using obstacles as cover!
The bosses you face in Once Human are beings massively corrupted by Stardust energy. You will encounter them while exploring, during quests, and in Monoliths. Some notable ones are considered as Great Ones, which hold control over an area of the game!
All Bosses Locations
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