Once Human

All Bosses Locations

Once Human - List of All Bosses

Bosses are notable Stardust-afflicted aberrants you will face in Once Human. Read on for a list of all bosses and elite enemies, including their location, weaknesses, tips to beat them, and the rewards you can get after defeating them!

List of All Bosses

Monolith Bosses

Lv. Boss Overview
10 Once Human - Ravenous HunterRavenous Hunter Location: Monolith of Greed
Weaknesses:
・Slime Head
Rewards: Melee Amplifier, Munitions Amplifier, Weapon Mod Parts, Stardust Source, Electronic Part
Notable Tips:
・Focus on the Gatling Gun lodged in its arm first
・Destroy the Eggs it spawns
・Camp near indestructible walls to safely remove the shadows
20 Once Human - TreantTreant Location: Gaia Cliff Monolith
Weaknesses:
・Woman Body
Rewards: Melee Amplifier, Munitions Amplifier, Weapon Mod Parts, Stardust Source, Electronic Part
Notable Tips:
・Exterminate the extra enemies first
・Position yourself where you can see the humanoid before destroying the vines
・Hiding behind cover mitigates almost all the Treant's attacks
30 Once Human - ArachsiamArachsiam Location: Mirage Monolith
Weaknesses:
・Pus-riddled Abdomen
・Head
Rewards: Energy Link, Gear Mod x2, Weapon Mod Parts, Stardust Source, Electronic Part
Notable Tips:
・Use Tactical Drone to increase visibility in smoke
・Focus on the little spiders for safety
・Use Fortress Warfare to avoid Poison Fog damage
40 Once Human - Shadow HoundShadow Hound Location: Monolith of Thirst
Weaknesses:
・Head
・Shoulders
Rewards: Energy Link, Gear Mod x2, Weapon Mod Parts, Stardust Source, Electronic Part
Notable Tips:
・Kill the lesser dogs first
・Position far away so Rabizex uses easy-to-avoid attacks

Elite Enemies

Boss Overview
Once Human - AgentAgent Location: Monolith of Greed
Weaknesses:
・Head
Rewards: Acid
Once Human - ArbiterArbiter Location: Hearst Industries
Weaknesses:
・Back
Rewards: Energy Link, Stardust Source, Acid, Eclipse Cortex Lv. 2
Once Human - BurrowerBurrower Location: Eastern Railway Junction
Weaknesses: TBD
Rewards: Acid
Once Human - Chagas WeevilChagas Weevil Location: Rotten Saddle
Weaknesses:
・Abdomen sac
Rewards: Energy Link, Stardust Source, Acid, Eclipse Cortex Lv. 1
Once Human - EdeEde Location: High Banks
Weaknesses:
・Balloons
Rewards: Energy Link, Stardust Source, Acid, Eclipse Cortex Lv. 1
Notable Tips:
・Attack the balloons that light up
Once Human - GhoulGhoul Location: Hearst Industries
Weaknesses: TBD
Rewards: Acid
Once Human - GluttonGlutton Location: Overlook Town
Weaknesses:
・Legs
・Head
Rewards: Energy Link, Acid, Eclipse Cortex Lv. 1
Notable Tips:
・Focus attacking the leg sores
・Attack the inside of the head when it falls to the ground
Once Human - GnawerGnawer Location: Overlook Town
Weaknesses:
・Head
Rewards: Acid
Once Human - MayhemMayhem Location: TBD
Weaknesses: TBD
Rewards: TBD
Once Human - Mirror GirlMirror Girl Location: Refinery Pollution Point
Weaknesses:
・Woman body
Rewards: Acid
Notable Tips:
・Focus shooting the body behind the mirror
・Avoid shooting the mirror as the bullets get deflected directly at you
Once Human - Mother of LifeMother of Life Location: Greenlake Hill
Weaknesses:
・Head
Rewards: TBD
Once Human - Rainfall ReaperRainfall Reaper Location: Sutherland Chemical Plant
Weaknesses:
・Umbrella
Rewards: Energy Link, Stardust Source, Acid, Eclipse Cortex Lv. 1
Notable Tips:
・Attack the top of the umbrella
Once Human - Rosetta BruiserRosetta Bruiser Location: Junkyard
Weaknesses: TBD
Rewards: Energy Link, Gunpowder, Eclipse Cortex Lv. 2
Notable Tips:
・Use throwable items such as grenades or molotovs to deal damage behind the shield
Once Human - Rosetta HeavyRosetta Heavy Location: Gaia Research Center Ruins
Weaknesses:
・Head
Rewards: Energy Link, Weapon Mod Parts, Rosetta V2 Access Card, Gunpowder, Eclipse Cortex Lv. 1
Once Human - Rosetta MechanicRosetta Mechanic Location: Junkyard
Weaknesses:
・Head
Rewards: Energy Link, Rosetta V2 Access Card, Gunpowder, Eclipse Cortex Lv. 2
Notable Tips:
・Shoot the drone on the back
Once Human - Rosetta SniperRosetta Sniper Location: Gaia Research Center Ruins
Weaknesses:
・Head
Rewards: Acid
Once Human - Sinner SentrySinner Sentry Location: Holt Town
Weaknesses:
・Traffic lights
Rewards: Energy Link, Stardust Source, Acid, Eclipse Cortex Lv. 1
Notable Tips:
・Shoot the traffic lights
・Fight from a distance
Once Human - Star WalkerStar Walker Location: Rotten Saddle
Weaknesses: TBD
Rewards: Acid
Once Human - The ButchersThe Butchers Location: Greenlake Hill
Weaknesses:
・Head
・Back
Rewards: Energy Link, Acid, Eclipse Cortex Lv. 1
Once Human - The ScorcherThe Scorcher Location: Eastern Railway Junction
Weaknesses:
・Head
Rewards: Acid
Once Human - WatcherWatcher Location: Brookham
Weaknesses:
・Head
Rewards: Acid
Notable Tips:
・Shoot the light in the head
Once Human - Weather ForecastWeather Forecast Location: Blackfell Fallen Zone
Weaknesses:
・Lit Television Head
Rewards: Energy Link, Artisan's Touch, Acid, Eclipse Cortex Lv. 1
Notable Tips:
・Focus attacking the lit television head
・Move around the area to avoid it attacks

General Boss Tips

Boss Tips



Follow the Recommended Amount of Players

Depending on the difficulty of the boss, there is a specific number of players that the game recommends to join. In most cases, it is wise to follow the game's advice since some bosses can be brutal without proper preparation!

Stock Up on Consumables

Consumables are crucial not only for your survival with healing but also allow you to stack buffs so you can deal more damage to bosses!

Bring the Appropriate Deviant

Each unique Deviant serves a different purpose, some designed better for combat! Look to bring a Deviant that aids you at specific phases of a boss.
Deviants Guide: All Deviant Locations

Organize Your Loadout

While your current build could be strong, some loadouts are better for specific bosses you face. For example, the Ravenous Hunter uses linear attacks with its Gatling Gun, so it is best to snipe it out while using obstacles as cover!

Bosses Explained

Stardust-Afflicted Aberrants

Once Human - Bosses Explained
The bosses you face in Once Human are beings massively corrupted by Stardust energy. You will encounter them while exploring, during quests, and in Monoliths. Some notable ones are considered as Great Ones, which hold control over an area of the game!

Once Human Related Guides

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