Kayron Best Team and Build
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This is a guide for the best teams and loadout for Kayron in Chaos Zero Nightmare (CZN). Learn which combatants are best to pair with Kayron, as well as recommended cards, partners, and equipment.
| Kayron Guides | |
|---|---|
| Team and Build | Cards and Materials |
List of Contents
Best Kayron Build
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|---|---|---|---|---|---|---|---|---|---|---|---|
 Summary |
 Best Team |
 Best Cards |
 Best Partner |
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 Memory Fragment |
 Equipment |
 Playstyle |
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Build Overview
※ Hover over equipments, memory fragments and cards to see effects
| Character | Partner | Equipment |
|---|---|---|
|
|
 Mutant Predator Spike Mutant Predator Spike When there are 4 or more cards in hand, increase Damage Amount by 30%
Wings of Freedom
Wings of Freedom When hit, +10% Damage Amount (Max 3 stacks)  Emblem of an Exceptional Entity Emblem of an Exceptional Entity +30% Damage Amount. Stress received becomes 0 (1 for each battle) |
| Memory Fragments and Stat Priorities | ||
 Offering of the Void Set Offering of the Void Set When a card is Exhausted, increase Damage Amount of Void Cards by 20% for 1 turn  Executioner's Tool Set Executioner's Tool Set +25% Critical Damage |
1. Void Damage % 2. Crit Chance % 3. Crit Damage % 4. Attack |
|
| Cards and Epiphanies | ||
 Echo of Futility 5
AP Cost: 0 Type:  Attack ・30% Damage ・Create 2 Futility card(s) ・+30% Damage equal to number of Futility created during his battle Echo of Futility 5
AP Cost: 0 Type: Attack ・30% Damage ・Create 2 Futility card(s) ・+30% Damage equal to number of Futility created during his battle Echo of Futility 5
AP Cost: 0 Type: Attack ・30% Damage ・Create 2 Futility card(s) ・+30% Damage equal to number of Futility created during his battle Echo of Futility 5
AP Cost: 0 Type: Attack ・30% Damage ・Create 2 Futility card(s) ・+30% Damage equal to number of Futility created during his battle  Brand of Annihiliation 3
AP Cost: 7: Type: Attack ・500% Damage to all enemies ・Decrease cost by number of Exhausted Futility 
 Oath of Vanity 3
AP Cost: 1 Type: Tags: Unique Upgrade ・When a Futility created, change it into a Cost 1 Attack card with 180% Damage effect  Echoes of True Abyss 0
AP Cost: 2 Type: Attack ・240% damage ・Create 3 Futility cards ・+40% Damage as that amount |
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Kayron's best build focuses on creating and exhausting a lot of Futility to increase the damage of his Black Hole and Echo of Futility cards to deal massive single-target damage. This build can be played two separate ways depending on how high the level of your Kayron's Manifest Ego.
For his Memory Fragments, our setup works best with a 4/2 set using Offering of the Void and Executioner's Edge. This lets you amp his offensive stat and gain a 20% multiplicative damage if he exhausted a card which Kayron does frequently. Multiplicative damage buff is the best type of buff he needs since all of his cards has the highest base damage multiplier out of any character.
His favored chaos zone is Laboratory 0 to get his best equipment such as Mutant Predator Spike for 30% multiplicative damage buff if there are 4 more cards in your hand. Wings of Freedom to get increasing 10% multiplicative damage buff after getting hit for a total of 3 times and Emblem of an Exceptional Entity for 30% additive damage buff to all of Kayron's attacks. Other chaos zones cannot offer all equipment slots that buffs damage especially multiplicative buffs hence why Laboratory 0 is the best option to get.
| Date | Changes |
|---|---|
| 01-12-2026 | ・Updated build overview ・Changed best team to Mika and Nia ・Changed best card reflect the Mika and Nia best team change ・Changed best equipment to Laboratory 0 ・Changed playstyle to accomodate Kayron with different manifest ego level |
| 11-18-2025 | ・Added Kayron build overview ・Revised Kayron build page layout |
| 10-26-2025 | ・Combined the 1-cost build and AoE burst into one viable setup. ・Updated recommended cards and playstyle. |
Kayron Best Team
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| Summary |
Best Team |
Best Cards |
Best Partner |
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| Memory Fragment |
Equipment |
Playstyle |
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| Support | Support |
|---|---|
 Mika
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 Nia
|
Kayron's best team is Mika and Nia as both of these characters can generate AP for him to use on his expensive cards without needing to have divine epiphanies. Mika can provide healing and AP recovery for Kayron as this build focuses more on damage rather than sustain while Nia only needs the Adagio and Eternal Hunger combo to generate a lot of AP and provide card draw to cycle the deck much faster.
Alternative Team Members
| Character | Explanation |
|---|---|
 Veronica
|
Can replace Nia or Mika as another Support or a Sub-DPS. She can draw a lot of cards and help with more damage from her ballista but at the cost of losing AP generation, healing and damage boost. |
 Rei
|
Can replace Nia or Mika as another Support. Despite her addtive buffs, she can still significantly increase Kayron's damage and thin out the deck if you have her at Manifest Ego 6 but you lose out on AP generation. |
 Cassius
|
Can replace Nia or Mika as another Support. You can utilize his ability to cycle and find Kayron's cards as much as possible however most of his buffs are additive which Kayron does not utilize well enough. |
Kayron Best Cards
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|---|---|---|---|---|---|---|---|---|---|---|---|
| Summary |
Best Team |
Best Cards |
Best Partner |
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| Memory Fragment |
Equipment |
Playstyle |
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| Card | Epiphany Effect |
|---|---|
|
Echo of Futility
|
AP Cost: 0
・30% Damage ・Create 2 Futility card(s) ・+30% Damage equal to number of Futility created during his battle |
|
Brand of Annihiliation
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AP Cost: 7
・500% Damage to all enemies ・Decrease cost by number of Exhausted Futility |
|
Black Hole
|
AP Cost: 2
・360% Damage ・+60% Damage per Exhausted Futility |
|
Oath of Vanity
|
AP Cost: 1
Tags: Unique ・When a Futility created, change it into a Cost 1 Attack card with 180% Damage effect |
Unlike most characters, Kayron has many viable builds but his most effective and strongest build revolves around generating and exhaust Futility to scale two of his main cards to deal the highest possible damage in a single hit and card.
His choice of epiphany for Echo of Futility is the 0 AP version that can generate Futility at the cost of lower base damage but higher scaling potential and lower AP cost. You need to create at least 25 futility to reach the scaling potential of the other similar epiphany that cost 1 AP. After that, it will scale better.
For Brand of Annihilation, the best epiphany is the 7 AP version as you only need to exhaust 7 Futility for it to cost 0 AP for the entire battle while Black Hole should be the much stronger version of its base effect so that it scales much faster and higher.
As for Oath of Vanity, you either go for the epiphany with the initiation tag only if your Kayron has Manifest Ego level 2 or below, or the 180% Futility damage epiphany if you have him at Manifest Ego level 3 and above.
Essential Team Cards and Epiphanies
| Card | Epiphany Effect |
|---|---|
 Source of Water
|
AP Cost: 0
・Heal 150% ・1 AP ・1 Wave |
 Blessing of Waves
|
AP Cost: 1
Tags: Retain ・Heal 150% ・+30% Healing equal to number of AP ・Shield equal to Healing amount exceeding max |
 Tactical Analysis
|
AP Cost: 0
・2 Wave ・For 1 turn, +100% own Healing |
 Soul Rip
|
AP Cost: 2
・When discarding a card, 1 Decibel |
 Adagio
|
AP Cost: 0
・Draw 2 ・Discard 2 ・With this effect, move discarded card to top of the Draw Pile |
 Forbidden: Eternal Hunger
|
AP Cost: 0
Tags: Retain, Exhaust ・Response: Draw 1, +1 AP |
Mika's epiphanies and card choice is very standard where all she needs are cards that generate a lot of wave stacks to get more AP recovery. If possible, have at least one of her cards have a divine epiphany specifically card draw to help cycle the deck more.
Nia, on the other hand, only needs Adagio with the discard epiphany that has more card draw and Eternal Hunger. This combo enables her to not only draw 1 more card but also generate AP for Kayron to use. The more Adagio copy she has, the more card draw and AP recovery she generates.
Kayron Best Partner
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|---|---|---|---|---|---|---|---|---|---|---|---|
| Summary |
Best Team |
Best Cards |
Best Partner |
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| Memory Fragment |
Equipment |
Playstyle |
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| Partner | Details |
|---|---|
 Bria
|
Passive Effect: Capable Secretary - When the assigned combatant generates a card, attack card damage is increased by 10% for 1 turn. Stacks up to 3 times. When the assigned combatant generates a Status ailment card for first time, +25% attack card damage for 1 turn Ego Skill: Check the Instructions - From the Discard Pile, Exhaust all Status Ailment (including cards changed from Status Ailment) and Curse cards. For each card Exhausted, +10% Designated Combatants' Attack card Damage for 1 turn |
Bria is the best partner for Kayron if for the AoE Burst and the ability to exhaust all Futilities in the discard pile whenever you wat. Her passive allows Kayron's cards to have more additive damage buff based on the amount of exhausted cards which can also help fuel the scaling of his cards without needing to use too much AP.
Alternative Budget Partner
| Partner | Details |
|---|---|
 Zatera
|
Zatera is a good partner for Kayron as Fortune Telling; their Psionic synergy allows Kayron to gain a damage increase to his Attack cards and adds more base attack to him. As a bonus, Kayron will be able to recover health if he is injured at the end of the battle. |
Kayron Best Memory Fragment
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|---|---|---|---|---|---|---|---|---|---|---|---|
| Summary |
Best Team |
Best Cards |
Best Partner |
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| Memory Fragment |
Equipment |
Playstyle |
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Offering of the Void Set Offering of the Void Set When a card is Exhausted, increase Damage Amount of Void Cards by 20% for 1 turn |
Executioner's Tool Set Executioner's Tool Set +25% Critical Damage |
The best set combination for this build is Offering of the Void (4-piece) and Executioner's Tool (2-piece). You can trigger the Offering of the Void damage bonus very consistently, since Kayron's futility card always exhausts when used, and gives him 20% multiplicative damage buff which he benefits a lot due to how high the base damage multipliers of his cards while Executioner's Tool improves his critical damage so he can deal even more damage after a critical strike.
Stat Priority
| Main Stats | Recommended Substats |
|---|---|
|
Ideal: Critical Chance % Desire: Void Damage % Imagination: Attack % |
・Critical Chance %
・Critical Damage % ・Attack ・Attack % |
The main stat and sub stats Kayron needs are Void Damage, Critical Chance, Critical Damage and Attack. His last potential node needs at least 600 attack which is easy to achieve and the more you have attack stats on him the more critical damage he gets.
Kayron Best Equipment
| Click on a Link to Jump to a Section! | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Summary |
Best Team |
Best Cards |
Best Partner |
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| Memory Fragment |
Equipment |
Playstyle |
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| Weapon | Armor | Accessory |
|---|---|---|
|
Mutant Predator Spike Mutant Predator Spike When there are 4 or more cards in hand, increase Damage Amount by 30% |
Wings of Freedom Wings of Freedom When hit, +10% Damage Amount (Max 3 stacks) |
Emblem of an Exceptional Entity Emblem of an Exceptional Entity +30% Damage Amount. Stress received becomes 0 (1 for each battle) |
Kayron's best equipment can only be found in Laboratory 0 with Mutant Predator Spike giving him 30% more multiplicative damage for all of his attacks as long as you have 4 or more cards in hand. Wings of Freedom for 10% more multiplicative damage each time your team gets hit up to 3 times.
Emblem of an Exceptional Entity is the best trinket slot for him as it has +30% additive damage to all of his attacks which is not much due to how his card multipliers are but enough as this is the best you can insert in this slot and chaos zone.
Dimensional Cube If You Can Discard 3 or More Cards Per Turn
 Dimensional Cube Dimensional Cube When discarding a card, +10% Damage for 1 turn |
Since this build uses Nia as a party member, you can swap Emblem of an Exceptional Entity with Dimensional Cube so that Kayron gets more additive damage but you need to discard 3 or more cards per turn to make it better than any trinket equipments. You also need to have level 30 exploration rewards for Blue Pot.
Alternative Budget Equipment
| Weapon | Armor | Accessory |
|---|---|---|
 Obsidian Sword Obsidian Sword Increase damage amount by 12% |
 Incomplete Carapace Incomplete Carapace At the end of the turn, if you have 3 or more Cards in hand, +140% Fixed Shield |
 Amorphous Cube Amorphous Cube +25% Damage |
If you aren't able to get the best, you can settle for these equipment that some can be found in any chaos zones inside shops. Obsidian Sword to boost the overall damage of all his attacks by 12% multiplicatively. Incomplete Carapace for shield if you have 5 or more cards in hand at the end of turn which is easily achievable by him but can only be found in Laboratory 0 and Amorphous Cube gives a permanent +25% additive damage buff to all of his attacks.
Kayron Build Tips and Playstyle
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|---|---|---|---|---|---|---|---|---|---|---|---|
| Summary |
Best Team |
Best Cards |
Best Partner |
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| Memory Fragment |
Equipment |
Playstyle |
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Manifest Ego 2 and Below Playstyle
Kayron's playstyle significantly changes based on the level of his manifest ego and whether he has access to Bria or not. If your Kayron is at Manifest Ego 2 and below, follow these steps to get the most of his cards:
- It is advised to get the epiphany for Oath of Vanity with the initiation tag for this playstyle.
- Generate Futility via Echo of Futility and Echoes of True Abyss to use it as an attack card while exhausting it at the same time.
- If you have 3 or more Futility in hand and you lack AP to use it, activate his Ego skill to exhaust it.
- (Optional) If you have Bria, only use her skill once you have 5 or more futility in your discard pile.
- Continue exhausting Futilities to strengthen your Black Hole and Echo of Futility.
Manifest Ego 3 and Above Playstyle
If you have Kayron at Manifest Ego 3 and above, his early turns will be different as your goal now is to setup the right turn to use his Ego skill or Bria's skill and exhaust a lot of Futility in your discard pile in one turn. Follow these steps to accelerate the amount of Futility you can exhaust:
- Since the epiphany of Oath of Vanity for this playstyle is not the one with the initiation tag, it is best to find it as soon as possible in your deck with card draws.
- If you haven't found Oath of Vanity, use your Echo of Futility and Echoes of True Abyss to generate Futility but not use it. It can function as a discard fodder.
- If you have found Oath of Vanity, play it and use as much AP to exhaust Futility while having enough to play other useful cards such as Black Hole or Echoes of True Abyss.
- Once you have 7 or more futility in your discard pile, you can use either Bria's skill or Kayron's Ego skill to exhaust it and get a massive damage boost to your cards.
- Continue exhausting Futilities to strengthen your Black Hole and Echo of Futility.
Existing Futility Does Not Convert to Attack Cards
Oath of Vanity converts Futility into attack cards but it does not make already generated and existing Futility into attack cards.
Black Hole and Echo of Futility Scales Infinitely
Most of Kayron's cards scales infinitely and adds the damage multiplier it gets once the condition is fulfilled to its base damage multiplier. What it means is that damage buffs especially multiplicative buffs will be affected by it so that the more you exhaust the higher the bonus damage you get from these buffs.
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