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This is a guide for the best teams and loadout for Kayron in Chaos Zero Nightmare (CZN). Learn which combatants are best to pair with Kayron, as well as recommended cards, partners, and equipment.
| Kayron Guides | |
|---|---|
| Team and Build | Cards and Materials |
Attention! |
This build is based on early impressions and the initial chapters of the game. We will continue adding more build variety and updating the current build as we dive deeper into the game! Sign in and select under the page's title to be notified of any updates! |
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List of Contents
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| DPS Party List | ||
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Kayron
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Mika
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Rei
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Kayron has access to single-target damage with his Black Hole or Echoes of Futility card. He also has AoE attacks with Brand of Annihilation and healing with Oath of Vanity. The longer the fight, the stronger his attacks become thanks to Rei and Mika's support that he lacks such as AP generation, buffs and more card exhausts.
| Date | Changes |
|---|---|
| 11-18-2025 | ・Added Kayron build overview
・Revised Kayron build page layout |
| 10-26-2025 | ・Combined the 1-cost build and AoE burst into one viable setup.
・Updated recommended cards and playstyle. |
| Click on a Link to Jump to a Section! | |||||||||||
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| Support | Sub-DPS |
|---|---|
Mika
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Rei
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Mika and Rei are Kayron's best teammates. Mika handles healing and AP generation support. Rei serves as the Sub-DPS, focusing primarily on buffing Kayron's Void cards.
| Character | Explanation |
|---|---|
Cassius
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Can replace Rei as the Card Puller of the team. You can utilize his ability to cycle Kayron's main DPS cards as much as possible. |
| Click on a Link to Jump to a Section! | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Card | Epiphany Effect |
|---|---|
Echo of Futility
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AP Cost: X
・50% Damage ・+150% Damage Amount by the same amount X ・Create X + 1 Futility card(s) |
Brand of Annihiliation
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AP Cost: 7:
・500% Damage to all enemies ・Decrease cost by number of Exhausted Futility |
Black Hole
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AP Cost: 2
・300% Damage ・+1 hit per 5 Exhausted Futility (Max 2) |
Oath of Vanity
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AP Cost: 0
Tags: Initiation, Unique ・Upon creating Futility, changes to an Attack card with 80% Damage and Healing effect, cost 1 |
Echoes of True Abyss
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AP Cost: 2
・240% damage ・Create 3 Futility cards ・+40% Damage as that amount |
The goal of this setup is to consistently deal damage while exhausting Futility cards, then unleash massive damage after exhausting many of them. The upgraded Echo of Futility (with the X cost) not only deals significant damage but also guarantees the creation of numerous Futility cards. Oath of Vanity, upgraded with the Outbreak of War tag, provides damage-dealing Futility cards right from the start, enabling a more consistent setup.
Choosing the 500% AoE damage (7-Cost) upgrade for Brand of Annihilation seems like a downgrade, but you can actually benefit more from this card in the long run since you will be creating and Exhausting a lot of Futility cards. Alternatively, you can choose the option where it hits twice instead of targeting all enemies; this becomes extremely potent against single targets like bosses.
Black Hole, with its upgrade adding an extra hit per 5 exhausted Futility cards, incentivizes you to spend Futility cards while increasing overall damage output. Lastly, Echoes of True Abyss will allow you to create even more Futility cards while dealing considerable damage.
| Card | Epiphany Effect |
|---|---|
Source of Water
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AP Cost: 0
・Heal 150% ・1 AP ・1 Wave |
Blessing of Waves
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AP Cost: 1
Tags: Retain ・Heal 150% ・+30% Healing equal to number of AP ・Shield equal to Healing amount exceeding max |
Tactical Analysis
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AP Cost: 0
・2 Wave ・For 1 turn, +100% own Healing |
Deluge
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AP Cost: 1
Tags: Unique ・1 Wave ・At the start of the turn, gain 1 Wave |
Strike of Darkness
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AP Cost: 0
Tags: Retain ・Activate all Basic cards in hand |
Resonating Darkness
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AP Cost: 1
Tags: Unique ・+40% Damage for Void Card |
Snack Time
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AP Cost: 0
Tags: Exhaust ・Select 2 card(s) in hand to Exhaust ・Select 1 Void card(s) to Draw |
Dark Condensation
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AP Cost: 1
・Select 1 Attack card(s), +100% Damage until used |
Predator's Blade
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AP Cost: 1
・250% Damage ・ For 1 turn 2 Morale |
For Rei's cards, the goal is to maintain maximum Void card buffs through upgrades like Resonating Darkness's Void damage increase, Dark Condensation's 100% boost to a specific card, and Predator's Blade's Morale buff. Snack Time helps set up plays by drawing a specific Void card while exhausting others. Additionally, Strike of Darkness offers a valuable quality-of-life improvement by saving AP when using basic healing cards from Rei or Mika.
Mika's cards are all about AP and Wave generation while keeping the team afloat through extensive healing.
| Click on a Link to Jump to a Section! | |||||||||||
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| Partner | Details |
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Bria
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Passive Effect: Capable Secretary - When the assigned combatant generates a card, attack card damage is increased by 10% for 1 turn. Stacks up to 3 times. When the assigned combatant generates a Status ailment card for first time, +25% attack card damage for 1 turn Ego Skill: Check the Instructions - From the Discard Pile, Exhaust all Status Ailment (including cards changed from Status Ailment) and Curse cards. For each card Exhausted, +10% Designated Combatants' Attack card Damage for 1 turn |
Bria is the best partner for Kayron if for the AoE Burst. Her passive allows Kayron's Black Hole to deal even more damage based on the exhausted cards which is already the main mechanic of the build.
| Partner | Details |
|---|---|
Eloise
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Eloise is a great 4-star option for Kayron as she increases his damage whenever he Exhausts a Futility Card. Her Ego Skill, although it is not offensive, can save you in instances where you might receive fatal damage. |
Zatera
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Zatera is a good partner for Kayron as Fortune Telling; their Psionic synergy allows Kayron to gain a damage increase to his Attack cards. As a bonus, Kayron will be able to recover health if he is injured at the end of the battle. |
| Click on a Link to Jump to a Section! | |||||||||||
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Offering of the Void Set Offering of the Void Set When a card is Exhausted, increase Damage Amount of Void Cards by 20% for 1 turn |
Black Wing Set Black Wing Set +12% Attack |
The best set combination for this build is Offering of the Void (4-piece) and Black Wing (2-piece). You can trigger the Offering of the Void damage bonus very consistently, since Kayron's futility card always exhausts when used. For both main stats and substats, aim for Void Damage, Critical Chance, Critical Damage, and Attack.
Executioner's Tool Set Executioner's Tool Set +25% Critical Damage |
If you want a higher damage ceiling, you can instead opt for the Executioner Set instead of the Black Wing to deal more damage on critical hits. However, we only recommend this set if you have sufficient Critical Chance to consistently take advantage of the Critical Damage increase, ideally maintaining approximately a 1:2 ratio between Critical Chance and Critical Damage.
We still highly recommend using the Offering of the Void and Black Wing combination initially, as it is more consistent and easier to farm.
| Click on a Link to Jump to a Section! | |||||||||||
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| Weapon | Armor | Accessory |
|---|---|---|
Void of the Devourer Void of the Devourer When a card is Exhausted, next card used +35% Damage stacks up to 1 time |
Regenerative Ribcage Regenerative Ribcage Max HP +12 |
Heart of the Jewel Heart of the Jewel X is applied as X+1 |
For Kayron's equipment, the most important piece is the Heart of the Jewel accessory, which enhances damage and Futility card creation through Echo of Futility. Void of the Devourer is also a very powerful offensive option, but you can settle for Dream of the Devoured as it provides the same effect, just with a lower multiplier. For your armor, Regenerative Ribcage offers the most consistent increase in survivability.
| Click on a Link to Jump to a Section! | |||||||||||
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The ideal burst setup requires some luck and setup, but it can end combat encounters quickly when executed correctly. The ideal rotation is as follows:
Since Echo of Futility in this build has an X-Cost, you can use the card even at 0 AP, and it will still give you 1 Futility card. Combining this with the Heart of the Jewel accessory allows you to create 2 Futility cards at no AP cost, which is more efficient than needing to draw the card again.

It is good to remember that you can check the Exhaust Pile and click on the burning card icon to see the number of Exhausted Futility cards since the start of battle. This will allow you to determine if you have Exhausted enough cards to trigger the additional hits of Black Hole.
One of the best features of Kayron is his ability to turn his Futility cards into both offensive and defensive tools. Try to acquire Oath of Vanity as early as possible during Chaos Manifestation runs, because this will significantly increase your chances of winning combat encounters.

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Kayron Best Team and Build



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