The First Descendant

Enzo Builds and How to Unlock

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First Descendant - Enzo

This is an Enzo build for normal and hard mode in The First Descendant. Read on to learn Enzo's best builds, how to unlock, basic info, skills, as well as Enzo's exclusive equipment and skins!

Best Hard Mode Enzo Build

Enzo Hard Mode Builds
Descendant Modules Weapons and Modules
Equipment Playstyle Tips
▼Jump to Normal Mode Builds▼

Enzo Hard Mode Build Showcase

Best Enzo Modules (Hard)

Note: You can scroll horizontally to show more modules.

This build revolves around using the Focus Fire skill with the Smithereens shotgun's guaranteed crits to have a surplus of High-Power Rounds for the Guardian R4.

The other modules focus on survival, cooldown reduction, and MP management. When fully maximized, this build should be able to tank some hits while never running out of explosive rounds to melt bosses with!

Descendant Modules

Alternative Modules for Boss Fights

Module Change Explanation
The First Descendant - Supply Firearm EnhancerSupply Firearm Enhancer If you prefer using the Tamer to the Guardian R4, this Skill Module will greatly increase your damage output on bosses.
The First Descendant - Spear and ShieldSpear and Shield > Any Element Antibody Bringing a specific elemental resistance will significantly improve survivability in boss fights.

If you prefer Machine Guns or Assault Rifles, it would be advisable to swap Focus Fire with Supply Firearm Enhancer and mod for Skill Duration. Slotting in this alternative skill module also allows you to help supply your allies with ammo since Focus Fire only applies to you.

Since Spear and Shield are slotted mainly for additional defenses, it is best to swap it out for any elemental antibody depending on the boss you are fighting.

Alternative Modules for Mobbing

Module Change Explanation
The First Descendant - MP AccelerantMP Accelerant > The First Descendant - Nimble FingersNimble Fingers More Skill Cooldown over Duration and MP

Since you will not be able to reliably proc criticals with Smithereens outside of Void Interceptions, it is recommended to swap out MP Accelerant for Nimble Fingers to have more up-time on Focus Fire!

Best Enzo Weapons and Modules (Hard)

Weapon Substat Priority
The First Descendant - SmithereensSmithereens • Bonus Firearm ATK (vs. Colossus)
• Firearm ATK
• Firearm Critical Hit Damage
• Round Per Magazine
The First Descendant - Guardian R4Guardian R4
• Bonus Firearm ATK Colossus (vs. Colossus)
• Explosive ATK
• Firearm Critical Hit Damage
• Attribute Status Effect Trigger Rate
• Any Elemental ATK (Optional)

Best Smithereen Modules

Note: You can only equip one Bullet Improvement module, so change depending on the enemy's elemental weakness.

Since criticals with the Smithereen are guaranteed, it is recommended to mod it solely with Firearm ATK and Critical Hit Damage. This weapon will be your duration primer for Focus Fire as it will quickly stack up its duration due to the guaranteed criticals.

While it is not your primary DPS weapon, it still packs a punch if modded correctly and sets up your Guardian R4 with enough ammo to transition back to using Focus Fire again!

Best Guardian R4 Modules

Note: You can only equip one Bullet Improvement module, so change depending on the enemy's elemental weakness.

The Guardian R4 will be your main damage due to one module, Strengthen First Shot. Since the Guardian R4 can only slot in one ammo per shot, Strengthen First Shot's massive 200% Explosive ATK increase is consistently applied every 10 seconds.

The buffed-up ATK stat then also applies to your slotted elemental damage, which significantly increases damage dealt to a colossi. This weapon also has a high base critical chance, so it is recommended to slot in mods that increase Firearm ATK, Reload Time, and Critical Hit Damage!

Weapon Modules

Best Enzo Equipment (Hard)

Equipment Substat Priority
The First Descendant - Materialized Phase ReactorMaterialized Phase Reactor • Skill Duration Up
• Skill Cooldown
• Skill Cost
• Non Attribute Skill Power Boost Ratio
The First Descendant - Annihilation Auxiliary PowerAnnihilation Auxiliary Power • Max HP
• MP Recovery Out of Combat
The First Descendant - Annihilation SensorAnnihilation Sensor • MP Recovery In Combat
• Max MP
The First Descendant - Annihilation MemoryAnnihilation Memory • DEF
• Shield Recovery In Combat
The First Descendant - Annihilation ProcessorAnnihilation Processor • Item Acquisition Distance Increase Modifier
• Max Shield

Note: External Components with set bonuses have fixed main stats.

One thing of note with Enzo is that Skill Power does not define the amount of ammunition replenished. Essentially, it would be better to focus the additional skill power on Dimension for Explosive Drone. For the substats, look for Skill Duration and Skill Cooldown to keep your essential skills for much longer!

As for the External Components, the Annihilation Set is a healthy mix between HP and Defense, so it is the perfect match for Enzo, especially if you reach 40,000 Defense! Furthermore, the set boosts your Skill Duration and incentivizes you to be upfront in the enemy's face. The trick here is to take damage intentionally until your health reaches 50%, then pop Enhance Combat Suit to activate and maintain the effect safely!

List of Reactors List of External Components

Enzo Playstyle Tips

Enzo Playstyle Tips



Prime Focus Fire with Smithereens

Starting the fight, use Smithereens to quickly stack up Focus Fire's duration. Optimally, you should spend about a whole magazine's worth before switching to the Guardian R4!

Always remember to switch into Smithereens every so often to increase the duration and avoid running out of ammo!

Use Reload Animation Cancel

To counteract the long wait time before being able to reload after firing, you can repeatedly click on the reload button to double your damage output.

Get the High Ground

The Guardian R4 fires shells at an arc, so aiming with it can be a little challenging. It is recommended to position yourself on high ground or continuously jump while aiming your shots. Doing so will help with accuracy problems!

Use Explosive Drone to Stun Enemies

During panic situations where you are surrounded by enemies and low on health, use your Explosive Drone to daze enemies in a pinch! Doing so will get you out of a pinch and possibly get a chance to restore some HP.

Best Normal Mode Enzo Build

Jump to a Section!
Best Modules Best Weapon and Modules
Best Reactor Best External Components
▲Jump to Hard Mode Builds▲

Best Enzo Modules (Normal)

Best Enzo Modules
Spear and Shield ImageSpear and Shield DEF +X%, Skill Power +X%
Time Distribution ImageTime Distribution Skill Cooldown -X%, Max HP +X%
Focus on Non-Attribute ImageFocus on Non-Attribute Non-Attribute Skill Power +X%, Skill Cooldown -X%
Maximize Duration ImageMaximize Duration Skill Duration +X%, Skill Power Modifier -X%
HP Amplification ImageHP Amplification Max HP +X%, Max Shield -X%
Skill Extension ImageSkill Extension Skill Duration +X%, applies only to certain skills for each Descendant
Increased DEF ImageIncreased DEF DEF +X%
Increased HP ImageIncreased HP Max HP +X%
Nimble Fingers ImageNimble Fingers Skill Cooldown -X%

This build revolves around keeping your main-line abilities up for an extended time, allowing you to abuse Shotguns and Launchers. The selected modules focus on maximizing Skill Duration, survivability, and lowering cooldowns.

Modules List

Best Enzo Weapon and Modules (Normal)

Weapon Substat Priority
The First Descendant - Guardian R4Guardian R4 • Bonus Firearm ATK (vs. Colossus)
• Explosive ATK
• Firearm Critical Hit Damage
• Attribute Status Effect Trigger Rate
Best Modules for Guardian R4
Action and Reaction ImageAction and Reaction Explosive ATK +X%, Recoil +X%.
Better Concentration ImageBetter Concentration Firearm Critical Hit Damage +X%
Recycling Genius ImageRecycling Genius Reload Time Modifier +X%
Rifling Reinforcement ImageRifling Reinforcement Explosive ATK +X%

The Guardian R4 is the best normal mode Launcher that Enzo can use. Your Reload Modifier acts as your fire rate for Guardian R4, so it is recommended to invest early in Recycling Genius as you go through normal mode!

List of All Weapons

Best Enzo Reactor (Normal)

Reactor Substat Priority
Materialized Phase Reactor ImageMaterialized Phase Reactor ・Skill Duration
・Skill Cost Down

During the early game, equip the highest level Materialized Phase Reactor you get. While your skill power does not define much with Enzo, it helps add damage to Explosive Drones! This build relies on Skill Duration and Skill Cost Down, so look out for those substats!

List of Reactors

Best Enzo External Components (Normal)

Set Set Effect
The First Descendant - Veteran MarksmanThe First Descendant - Veteran MarksmanThe First Descendant - Veteran MarksmanThe First Descendant - Veteran Marksman
Veteran Marksman Set
2-Set Effect:
・Firearm Critical Rate +5.1%
4-Set Effect:
・Firearm ATK +6.6%
・Weak Point DMG +5.8%
Substat Priority
Auxiliary Power ・Max HP
・Fire Resistance
・Kuiper Shard Drop Rate Increase Modifier
・Module Drop Rate Increase Modifier
Sensor ・MP Recovery in Combat
・Max MP
・Consumable Drop Rate Increase Modifier
・Character EXP Gain
Memory ・DEF
・Electric Resistance
・Firearm Proficiency Gain Modifier
・Gold Drop Rate Increase Modifier
Processor ・Max Shield
・Item Acquisition Distance Increase Modifier
・Toxic Resistance
・Equipment Drop Rate Increase Modifier

Enzo's whole playstyle revolves around utilizing weapons to their utmost potential. With Veteran Marksman's set bonus, you can reliably increase your firearm damage output by hitting more criticals.

List of External Components

How to Unlock Enzo

Unlock Using the Research Institute

Research Time Cost
16:00:00 400,000
Required Research Material How to Get
Enzo Code x1 ・Intercept Battle: (Common) (Dead Bride) Amorphous Material Pattern: 025 required
・ Intercept Battle: (Common) (Hanged Man) Amorphous Material Pattern: 053
・ Agna Desert (Hard) - Abyssal Void Fusion Reactor - Agna Desert Miragestone Deposit
・ White-night Gulch (Normal) - Void Fusion Reactor - White-night Gulch Hatchery
Enzo Enhanced Cells x1 ・Research
Research Materials Needed:
Monomolecular Extractor x499
Flectorite x292
Inorganic Biogel x58
Enzo Enhanced Cells Blueprint x1
Enzo Spiral Catalyst x1 ・Research
Research Materials Needed:
Semi-permanent Plasma x290
Ceramic Composite x408
Positive Ion Particle x42
Enzo Spiral Catalyst Blueprint x1
Enzo Stabilizer x1 ・Research
Research Materials Needed:
Silicon x430
Nanopolymers x363
Advanced Neural Circuit x90
Enzo Stabilizer Blueprint x1

You can unlock Enzo through the Research Institute in Albion. Note that to acquire a Descendant using research, you need all the required items and gold to unlock this character.

Research Institute

Purchase Enzo Using Caliber

Purchase Descendants Using Caliber
Alternatively, you can unlock Descendants by purchasing them in the Shop. This method only requires Caliber, an in-game currency that you can buy with real money. Purchasing Enzo in the Shop instantly unlocks the Descendant, allowing you to skip the item requirements and research time.

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Enzo Basic Info & Stats

Enzo Basic Info
The First Descendant - Enzo IconEnzo

The Best Quartermaster
Role Support
Element
The First Descendant - Non-Attribute IconNon-Attribute
Description
"A supporter who uses supply drones. Commands the battlefield by supplying ammo to allies while launching long-range attacks with drones at the same time."

Stats

DEF Max Shield Shield Recovery Max MP Max HP
1674 516 3.96 187 841

Enzo Skills

Passive Skills

Skill Type
Effect
The First Descendant - Shoot Support IconShoot Support Grants Fire Support to allies within an area around Enzo, increasing their max ammo capacity. This efficiency of this effect increases marginally with the number of Enzos in the squad. Efficiency increases when Enzo disarms the security of the Encrypted Vault, and rewards increase when this happens.

Active Skills

Skill Type
Effect
The First Descendant - Start Supply IconStart Supply
The First Descendant - Singular Icon Singular

Summons a Bullet Supplying Device at the designated location. Supplies bullets to allies that approach the Device. The Bullet Supplying Device can be used once by each ally, and disappears when everyone has used it or its duration ends.
The First Descendant - Explosive Drone IconExplosive Drone
The First Descendant - Dimension Icon Dimension

Launches an Explosive Drone forward. The Explosive Drone explodes on contact with an enemy or a terrain object, dealing damage.
The First Descendant - Enhance Combat Suit IconEnhance Combat Suit
The First Descendant - Dimension Icon Dimension

Summons a Shield Recovery Comms. When the Shield Recovery Comms is first summoned, recovers Enzo's Energy Shield by a certain amount, then continues to recover the Energy Shield through Enhance Combat Suit effect.
The First Descendant - Perfect Support IconPerfect Support
The First Descendant - Singular Icon Singular

Summons a Small Supply Ship to himself and his allies. The Small Supply Ship periodically provides Supply Bullets and grants Perfect Support to allies. The Small Supply Ship attacks enemies in front while it is active, and when the skill ends, it fires a missile forward that causes a big explosion at its destination.

Enzo Exclusive Equipment

Arche Refrigerant Release Drone

The Arche Refrigerant Release Drone is a battle sub-system modified specifically for Enzo. It uses thermal sensors to automatically track down and attack the Vulgus who become colder than their surroundings, i.e. enemies that have been attacked by Enzo.

The drone is linked to Enzo's Arche; when Enzo uses her abilities, the drone is summoned automatically.
Various drone technologies have been researched to enhance Enzo's battle capabilities. The very first fruit of such efforts was the Arche Refrigerant Release Drone. Since then, it became possible to link the Arche of other Descendants to dedicated drones and turrets, and Enzo would sometimes joke that she was what started the Arche drone technology."

Enzo Skins

Jump to a Skin type!
Head Body Back
Chest Ecive Full Body
Grappling Hook Make Up Spawn

All Enzo Head Skins

Enzo's Barn-Owl Black Sunglasses Leaf Cut

All Enzo Body Skins

Enzo's Barn-Owl Morning Star Obsidian
Summer Vacation

All Enzo Back Skins

Baby Panda Ammo Supply Box White Rabbit Doll
Bear Cub Satellite Albion Rocket
Planetary Projector Rocket Jet Pack Double Z Wing
Run, Hamster Advanced Material Backpack Pink Salamander
Firefighting Tank

All Enzo Chest Skins

Small Flashlight HQ Access Card Old Teddy Bear
Bunny-Ears Strap Dynamite Brave Squirrel
Emote Tag Magister Researcher Mark of Albion
Recorder

All Enzo Ecive Skins

Continuity Bio Scan Heart

All Enzo Full Body Skins

Panda's Adventure Dinosaur Pajamas

All Enzo Grappling Hook Skins

Special Supply Advanced Material Engineering

All Enzo Make Up Skins

Fifty-Fifty Cross Scratch

All Enzo Spawn Skins

Magical Moment Passion Dismantling and Fusion
Snowman Beyond the Unknown Thunder and Lightning
Gale Big Water Bomb Wrong Direction

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Comment

1 Anonymous4 months

Can this please be updated? AFAIK HP Amplification and Battle of Stamina share HP-Class Modifcation and cant be used together. This may also is present in multiple other guides and builds for other characters.

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