This is a Python build in The First Descendant. Read on to learn the Python's best build, how to get Python, its stats, and more!

Best Python Build

Substats Priority
・Firearm ATK ・Rounds per Magazine ・Weak Point Damage ・Recoil
Best Modules for Python
Consume Magazines	Reload Time Modifier +X%, Weak Point Damage +X%
Fixed Shot	Recoil -X%, Weak Point Damage +X%
Maximize Weight Balance	Rounds per Magazine +X%, Weak Point Damage +X%
Pinpoint Shot	Firearm ATK +X%, Weak Point Damage +X%
Have Aiming	Weak Point Damage +X%, Accuracy -X%
Weak Point Sight	Weak Point Damage +X%
Expand Weapon Charge	Rounds per Magazine +X%
Vibration Absorption	Recoil -X%
Fire Rate UP	Fire Rate +X%
Rifling Reinforcement	Firearm ATK +X%

The Python is a submachine gun with an extremely high Fire Rate and a powerful Unique Ability that lowers the Non-Attribute resistance of your target by aiming at their Weak Points. Despite its strong Recoil and low base Critical Hit Rate, it remains an excellent weapon because you can equip Modules to compensate for its weaknesses.

By using Recoil modules, you can gain better control of the Python, making it easier to target the enemy's Weak Points and trigger the weapon's unique ability. Additionally, you can equip modules that increase the weapon's Fire Rate and Magazine capacity to improve damage output.

How to Get Python

Collect Research Materials

Research Cost and Required Mastery Rank

Go to Anais and Research the Weapon

Once you have the research materials, enough gold, and the required Mastery Rank, talk to Anais at Albion and select “Request Research”.

In the Weapons tab, select the weapon you want to research and select “Research Request” to start researching the weapon.

It will take 4 hours to research one ultimate weapon but you can research up to 5 ultimate weapons simultaneously!

Python Basic Info & Stats

Basic Info

Python Basic Info
Python	Tier	Ultimate
	Type	Submachine Gun
	Ammo	General Rounds
Unique Ability
Python Instinct: On hitting a Weak Point, inflicts the unique ability Prey on the target enemy.

Stats

The stats here are only at level 1.

Python Recommended Descendants

Descendant	Explanation
Freyna	Unique Ability lowers the Toxic Resistance of your target.
Gley	When using Massacre, the Python's fire rate is transferred to your Unique Weapon, but the damage output scales based on your Non-Attribute and Dimension Skill Power stats.

The First Descendant Related Guides

List of All Weapons

Weapon Rounds

Weapon Rarities

Weapon Types

All Weapons Using General Rounds

Cygnus	Ominous Hound	Albinism	Hungry Hound
Magnus AA	Red Wolf	Millenium Frost	Rose of Aisha
New Beginning	Devil's Call	Blue Blood Bloomer	Alter Ego
Firefly	Rascal V-51	Unfinished Study	Lion of Blue Mane
Tamer	Caligo's Horn	Phantom Pain	Eternal Willpower
The Last Dagger	The Final Masterpiece	Thunder Cage	Python
Enduring Legacy	Albion Cavalry Gun	Fallen Hope	Divine Punishment