Nihility is one of the Paths you can choose in the Simulated Universe of Honkai: Star Rail. See how to unlock it, how to use it, the best characters that can use it, the path's buffs, and all the Nihility Blessings here!

How to Unlock Path of Nihility

Play World 4 of Simulated Universe

The Path of Nihility unlocks after playing or clearing the World 4 in the Simulated Universe. Even if you fail to clear the World, it will automatically be unlocked and can be selected once you are starting another run.

Simulated Universe World 4 Guide

Also Available in Swarm Disaster

The Path of Nihility is also available in the Swarm Disaster, the most recent addition to the Simulated Universe. Here, the Path of Nihility and its Blessings needs to be unlocked by having a challenge get interrupted in Swarm Disaster.

Simulated Universe Swarm Disaster Guide

Also Available in Gold and Gears

The Path of Nihility is also available in Gold and Gears. Here, the Path of Nihility and its Blessings are already unlocked and can be used immediately!

Simulated Universe Gold and Gears Guide

Path of Nihility Information

Provides Status Effects

The Path of Nihility mainly uses status effects as its core. Its Blessings provide improved Break Effect, Break Efficiency, increased DoT damage, and Suspicion which is a debuff for enemies that increases DoT damage taken.

Revolves Around Damage Over Time

The Path of Nihility's Blessings revolves around DoT and its Path Resonance is no different. Its Path Resonance applies DoT status effects to all enemies for two turns, which deals more damage the more buffs you get for DoT.

How to Use Path of Nihility

In Simulated Universe

The Path of Nihility in the Simulated Universe works by allowing your characters to deal increased DoT damage while also giving them a way to apply and trigger DoT without having to wait for the enemy's turn. This makes a DoT-focused party perform very well.

The only drawback with the Path of Nihility is that it only works well with characters that specialize in dealing DoT damage.

Focus on Damage Over Time

Since the Path of Nihility's main thing is buffing DoT, play around it. The Path Resonance applies DoT effects for two turns and amplifies DoT effects, while its Blessings can add more ways for you to apply DoT.

Capitalize on this and make sure to get Nihility Blessings so you can upgrade the Path Resonance and make it have more effects, such as increasing DoT duration. Obtaining more Blessings also means more DoT buffs for your party, so it is always a win-win situation.

Get Destruction and The Hunt Blessings

For you to maximize the DoT boost that Nihility Blessings gives, you need to have high ATK and Speed for more turns. You can use Destruction Blessings that provide a lot of ATK to increase damage DoTs do or The Hunt Blessings that increase Speed to get more turns.

Having Blessings that increase Effect Hit Rate and reduce enemy Effect RES is also good! If you need defensive Blessings, you can also get some from Preservation or Abundance.

In Swarm Disaster

In Swarm Disaster, the mechanics for Paths have an additional function. Swarm Disaster introduces a board that you traverse to enter different domains. Each Path affects the board by modifying it in a way based on their Audience Die.

The Path of Nihility's Audience Die alters the board by turning domains into Blank domains, which turn into random domains when you enter them.

Enter Blank Domains

Since the Path of Nihility turns domains into Blank domains, always entering them will be beneficial. Some Dice Effects reward you with a Curio or Blessing while turning domains to Blank, so make sure to use each Dice Effect to your advantage!

Using the Dice Effect Transition, you can turn a Blank domain into a Reward domain which provides you with different rewards. The Dice Effect Nothingness gives you Cosmic Fragments when entering a Blank Domain.

Increase DoT Damage With Blank Domains

While using the Path of Nihility in the Swarm Disaster, whenever you enter a Blank domain you obtain a stacking DoT damage boost for your party that lasts throughout the run.

This gives more incentive to only enter Blank domains since you want to take advantage of this continuous effect.

Use The Hunt and Propagation Resonance Interplay

With Resonance Interplay in Swarm Disaster, getting three Blessings of The Hunt and Propagation is a must. The buffs they provide to the Path Resonance are invaluable and can be used to make your run easier, so take advantage of them!

Keep in mind that only three Blessings of each Path are required to activate their respective Resonance Interplays, so you don't need to get more Blessings after unless you want to.

Get Defensive Blessings

Aside from Resonance Interplay, defensive Blessings still pair well with the Path of Nihility here in Swarm Disaster. Enemies in the Swarm Disaster hit like a truck, especially the The Swarm - True Sting.

Preservation and Abundance Blessings provide you with shields and increased healing. Since Nihillity focuses on DoT damage, it is good to get some defensive Blessings to guarantee your party's safety.

In Gold and Gears

The Path of Nihility increases DoT DMG dealt by all allies whenever you meet the conditions for the Custom Dice's passive effects. With this, it is important to understand how your chosen Custom Dice's passive effect works since it is different for every type!

Best Characters for Path of Nihility

Best Characters and Explanation

Character	Explanation
Kafka	This Path is amazing for Kafka since Kafka's Skill already activates DoT. The Nihility Blessings just increase her DoT damage even more and allow her to trigger DoT more.
Sampo	Sampo is a great pick when using the Path of Nihility since his kit revolves around him inflicting Wind Shear and applying DoT vulnerability using his Ultimate.
Luka	Luka's kit goes well with Path of Nihility since Luka can inflict Bleed and his Ultimate can increase damage taken by enemies.
Serval	Serval plays well with Path of Nihility since her kit focuses on her applying Shock and extending it using her Ultimate. Nihility Blessings increase her DoT damage and make them last longer.

Overall, Path of Nihility is great for characters who apply DoT or status effects. The Path's buffs and Blessings can help them deal more damage through DoT, all while making it last longer and giving them more ways to trigger it.

Best Path of Nihility Blessings

Best Blessings and Explanation

Blessing Title	Effects
Funeral of Sensory Pursuivant ★★★	Effect: Every time an enemy takes DMG from a DoT, applies 1 stack(s) of Suspicion. Enhanced Effect: Every time an enemy receives a DoT, apply 1 stack(s) of Suspicion. Suspicion stacks will not be reduced.
The Man in the Cover ★★★	Effect: Every time an enemy is afflicted with a DoT, apply 3 stack(s) of Suspicion. Enhanced Effect: Every time an enemy is afflicted with a DoT, apply 3 stack(s) of Suspicion. Every time the DoT refreshes, apply 1 stack(s) of Suspicion.
Cafe Self-Deceit ★★	Effect: When an enemy has Suspicion on them, inflicts 1 extra stack(s) of Suspicion. Enhanced Effect: When an enemy is inflicted with Suspicion, the stack it gains are doubled.
All Things Are Possible ★★	Effect: If an enemy is attacked while under any DoT statuses, a random DoT will be triggered, dealing DMG equal to 100% of the DoT. Enhanced Effect: If an enemy is attacked while under any DoT statuses, a random DoT will be triggered, dealing DMG equal to 150% of the DoT.
Hell is Other People ★★	Effect: When a character inflicts Weakness Break on an enemy, the same type of Weakness Break effect is applied to enemies adjacent to it. Enhanced Effect: When a character inflicts Weakness Break on an enemy, the same type of Weakness Break effect is applied to all enemies.
Night Beyond Pyre ★★	Effect: Increases Weakness Break efficiency by 30%. Enhanced Effect: Increases Weakness Break efficiency by 45%.
Blind Vision ★	Effect: Reduces enemies' Effect RES by 12%. Enhanced Effect: Reduces enemies' Effect RES by 18%.
Questioning of Purpose ★	Effect: Increases characters' Break Effect by 50%. Enhanced Effect: Increases characters' Break Effect by 75%.

Funeral of Sensory Pursuivant

This Blessing allows you to apply Suspicion when an enemy takes DMG from a DoT. It is a must-have Blessing while running the Path of Nihility since it lets you stack Suspicion easier.

The Man in the Cover

This Blessing gives you another way to apply Suspicion, which is whenever they get a DoT. This is always great to have while running Path of Nihility because it lets you stack Suspicion faster.

Cafe Self-Deceit

This Blessing lets you inflict extra Suspicion when they already have existing Suspicion stacks. It is great to have since it lets you stack Suspicion faster, which means more DoT damage taken for the enemy.

All Things Are Possible

This is a great Blessing to pick up when using any Path and you're running some DoT characters. This allows you to trigger DoT without waiting for the enemy's turn, which is just more damage.

Hell is Other People

This Blessing spreads a Weakness Break effect, which can help you get some more damage in. This Blessing can be used while running any Path.

Night Beyond Pyre

This Blessing is always a great pick-up because it allows you to break Toughness faster. This can be used while running any Path and is always a good choice.

Blind Vision

This Blessing is a great pick-up since it lets debuffs inflicted by allies have a higher chance of being inflicted on enemies.

Questioning of Purpose

This Blessing is a nice pick-up if you want an increased Break Effect for your party. It lets any character deal more damage when inflicting Weakness Break.

Path of Nihility Buffs and Blessings

Simulated Universe

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Simulated Universe	Swarm Disaster	Gold and Gears

Path Buffs

Path of Nihility
Buffs	Increases the characters' DoT by 15%
	Increases the chance for Blessings of Nihility to appear
	Obtain 1 Resonance Formation when 6/10/14 Blessings of Nihility have been obtained.
Effects	Suspicion Debuff brought by certain Nihility Blessings. Increase DoT taken by 1%. Stacks up to 99 times, but loses 2 Stacks at the end of the turn.
	Confusion When enemies are Weakness Broken, every stack of Confusion will cause all DoTs currently on the enemy to deal DMG equal to 30% of their original DoT. Consumes 1 stack of Confusion. Confusion can stack up to 5 times.
	Devoid Each stack reduces Toughness regeneration by 10%, stacking up to 5 times.

Path Resonance

Blessing	Effect
Nihility ★★★	Effect: Spend 100 points of Energy to use this ability and resonate with the Path of Nihility, with 80% base chance to apply Burn, Shock, Bleed, and 2 stacks of Wind Shear on all enemies for 2 turn(s). Activated when 3 Blessings of Nihility have been obtained.

Resonance Formation

Blessing	Effect
Outsider ★★★	Effect: When entering battle, Path Resonance regenerates 40% Energy. When an enemy receives DoT, Path resonance additionally regenerates 2% Energy.
Suffering and Sunshine ★★★	Effect: The attacks of Path: The Nihility has a 100% base chance to inflict 2 stacks of Confusion and 2 stacks of Devoid on all enemies for 2 turn(s).
The Doubtful Fourfold Root ★★★	Effect: When using Path Resonance, increases the base chance of applying statuses by 100%, the duration of statuses by 1 turn, and adds 1 stack to all stackable statuses..

Blessings of Nihility

Blessing	Effect
Funeral of Sensory Pursuivant ★★★	Effect: Every time an enemy takes DMG from a DoT, applies 1 stack(s) of Suspicion. Enhanced Effect: Every time an enemy receives a DoT, apply 1 stack(s) of Suspicion. Suspicion stacks will not be reduced.
The Man in the Cover ★★★	Effect: Every time an enemy is afflicted with a DoT, apply 3 stack(s) of Suspicion. Enhanced Effect: Every time an enemy is afflicted with a DoT, apply 3 stack(s) of Suspicion. Every time the DoT refreshes, apply 1 stack(s) of Suspicion.
Why Hasn't Everything Already Disappeared? ★★★	Effect: At the beginning of an enemy's Turn, trigger extra DoT 1 time, dealing DMG equal to 90% of the original DoT. Enhanced Effect: At the beginning of an enemy's Turn, trigger extra DoT 1 time, dealing DMG equal to 135% of the original DoT.
Cafe Self-Deceit ★★	Effect: When an enemy has Suspicion on them, inflicts 1 extra stack(s) of Suspicion Enhanced Effect: When an enemy is inflicted with Suspicion, the stack it gains are doubled.
Twilight of Existence ★★	Effect: When hitting a Weakness Broken enemy, there is a 75% base chance to apply Burn, Shock, Bleed, or Wind Shear on the enemy for 2 turn(s). Enhanced Effect: When hitting a Weakness Broken enemy, there is a 75% base chance to apply Burn, Shock, Bleed, or Wind Shear on the enemy for 2 turn(s) and dispels 1 debuff currently on the attacker.
All Things are Possible ★★	Effect: If an enemy is attacked while under any DoT statuses, a random DoT will be triggered, dealing DMG equal to 100% of the DoT. Enhanced Effect: If an enemy is attacked while under any DoT statuses, a random DoT will be triggered, dealing DMG equal to 150% of the DoT.
Hell is Other People ★★	Effect: When a character inflicts Weakness Break on an enemy, the same type of Weakness Break effect is applied to enemies adjacent to it. Enhanced Effect: When a character inflicts Weakness Break on an enemy, the same type of Weakness Break effect is applied to all enemies.
Call of the Wilderness ★★	Effect: For every stack of Suspicion the enemies have, reduces their ATK by 0.3%, up to a max of 30%. Enhanced Effect: For every stack of Suspicion the enemies have, reduces their ATK by 0.4%, up to a max of 30%, and reduces their Effect RES by 0.4%, up to a max of 30%
Night Beyond Pyre ★★	Effect: Increases Weakness Break efficiency by 30%. Enhanced Effect: Increases Weakness Break efficiency by 45%.
Beginning and End ★★	Effect: When an enemy inflicted with Suspicion is defeated, inflicts the same number of stacks of Suspicion the defeated enemy has on 1 random enemy target(s). Enhanced Effect: When an enemy inflicted with Suspicion is defeated, inflicts the same number of stacks of Suspicion the defeated enemy has on 2 random enemy target(s).
Emotional Decluttering ★	Effect: Every time an enemy target is afflicted with a DoT status, the DMG taken by them increases by 3%. This effect can stack up to 4 time(s). Enhanced Effect: Every time an enemy target is afflicted with a DoT status, the DMG taken by them increases by 4%. This effect can stack up to 5 time(s).
Blind Vision ★	Effect: Reduces enemies' Effect RES by 12%. Enhanced Effect: Reduces enemies' Effect RES by 18%.
Before Sunrise ★	Effect: Every time an enemy receives a DoT, 2.0 Energy is regenerated for a random ally. Enhanced Effect: Every time an enemy receives a DoT, 3.0 Energy is regenerated for a random ally.
Offerings of Deception ★	Effect: Every time an enemy takes DMG from a DoT, all allies restore HP equal to 1.0% of their respective Max HP. Enhanced Effect: Every time an enemy takes DMG from a DoT, all allies restore HP equal to 1.5% of their respective Max HP.
Questioning of Purpose ★	Effect: Increases characters' Break Effect by 50%. Enhanced Effect: Increases characters' Break Effect by 75%.
Sensory Labyrinth ★	Effect: Extends the duration of Wind Shear, Bleed, Shock, and Burn on enemies by 1 turn(s). Enhanced Effect: Extends the duration of Wind Shear, Bleed, Shock, and Burn on enemies by 2 turn(s).
Tragic Lecture ★	Effect: Increases DoT taken by enemies by 10%. Enhanced Effect: Increases DoT taken by enemies by 15%.
Ignosticism ★	Effect: Gains a 6% DoT increase for each Nihility Blessing. This effect can stack up to a max of 6 times(s). Enhanced Effect: Gains an 8% DoT increase for each Nihility Blessing. This effect can stack up to a max of 9 times(s).

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Swarm Disaster

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Simulated Universe	Swarm Disaster	Gold and Gears

Audience Dice

Swarm Disaster: Path of Nihility
Buffs	More Blank Domains have appeared. Entering them will trigger random effects.
	Dimension Effect: When the first or second plane begins, turn 2 random domains into a Blank domain.
	Continuous Effect: When allies enter a Blank domain, its content will be immediately replaced with a domain of a random type. For every Blank domain that allies have entered, DoT damage dealt by all allies increases by 18%.
	Upon receiving 3 Blessings of Nihility, you will also receive 3 Blessings of The Hunt and 3 Blessings of Propagation, allowing for the respective activation of the corresponding Resonance Interplay.

Dice Effect

Name	Effect
Nihility: Transition	Effect: The content of Blank domain entered during this turn will be replaced by Reward domain
Nihility: Form	Effect: Immediately obtain 1 Curio and turn all Reward domains into Blank domains. (This effect will no longer be generated after appearing once on each plane)
Nihility: Shadow	Effect: Immediately obtain 1 Curio and turn all Elite domains into Blank domains. (This effect will no longer be generated after appearing once on each plane)
Nihility: Void	Effect: Immediately obtain 1 Curio and turn all Combat domains into Blank domains. (This effect will no longer be generated after appearing once on each plane)
Nihility: Dormancy	Effect: Immediately obtain 1 Curio and turn all Occurrence domains into Blank domains. (This effect will no longer be generated after appearing once on each plane)
Nihility: Nothingness	Effect: When allies enter Blank domain in this round, immediately obtain 10 Cosmic Fragments

Resonance Interplay

Blessing	Effect
Off the Beaten Track ★★★	Effect: After using a Path Resonance, for every type of debuff (out of Burn, Shock, Bleed, and Wind Shear) the enemy target is currently inflicted with, Advance Forward all allies' actions by 4%.
White Nights ★★★	Effect: A character's Basic ATK can cause all DoTs currently applied on the target via Path Resonance: Nihility to immediately deal DMG equivalent to 40% of these statuses' original DMG.

In addition to Path Resonance, Resonance Interplay is a new addition available in Swarm Disaster. The Path of Nihility has Resonance Interplay with both The Hunt and Propagation.

This provides its Path Resonance with Advance Forward for allies and a DoT trigger on Basic ATK.

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Gold and Gears

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Simulated Universe	Swarm Disaster	Gold and Gears

Path Boost

Gold and Gears: Path of Nihility
Buff	When the conditions for the Custom Dice's passive effects are met, you will receive the enhancement: Increased DoT DMG from all allies.
Activation Conditions	Path Resonance can be activated when 3 Blessings of Nihility have been obtained, and Resonance Formation can be activated when 6/10/14 have been obtained.
	If you obtain 3 Blessings of Remembrance or 3 Blessings of Elation while you already have 3 Blessings of Nihility, you can activate the respective Resonance Interplay.

Resonance Interplay

Blessing	Effect
Reign of Keys ★★★	Effect: Path Resonance deals 30% more DMG to Frozen enemies. When enemy targets become Frozen, DoTs applied by the Path Resonance extend their duration by 1 turn(s).
Terror and Tremble ★★★	Effect: For each unique Type of non-DOT DMG the enemy target has taken, Path Resonance deals 6% more DMG to it, lasting until the end of the turn.

Resonance Interplay, a feature introduced in Swarm Disaster, is also available in Gold and Gears. The Path of Nihility has Resonance Interplay with both Remembrance and Elation, which provide bonus effects after using Path Resonance.

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Honkai: Star Rail Related Guides

Simulated Universe Guide

Simulated Universe Stage Guides

Simulated Universe Guides
World 1	World 2	World 3
World 4	World 5	World 6
World 7	World 8	World 9

Paths and Blessing Guides

All Simulated Universe Paths
Propagation	Preservation	Abundance
Nihility	The Hunt	Remembrance
Destruction	Elation	Erudition

Swarm Disaster Guides

Simulated Universe: The Swarm Disaster Guides
The Swarm Disaster Guide	How to Unlock All Chapters
Communing Trail and Pathstrider Guide	Exploration Guide
How to Clear Difficulty 5

Gold and Gears Guides

Simulated Universe: Gold and Gears Guides
Gold and Gears Guide	How to Unlock All Trailblaze and Aeon Secrets
Neural Network Guide	Dice Customization and All Dice Faces
How to Beat Difficulty 5

Divergent Universe Guides

Divergent Universe: The Human Comedy
Divergent Universe Guide	How to Increase Synchronicity Level
How to Get Weighted Curios	Probability Museum Guide
How to Perform Curio Synthesis	How to Overwrite Weighted Curios
Divergent Universe Curios

Unknowable Domain Guides

Simulated Universe: Unknowable Domain
Unknowable Domain Guide	How to Beat Someone's Mausoleum

Other Simulated Universe Guides

Simulated Universe Guides
List of All Paths	Simulated Universe Events
List of All Curios	Resonance Interplay Guide