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Absolute Failure Prescription is a Curio in Honkai Star Rail's Divergent Universe. See how to get Absolute Failure Prescription and its effects in this guide!
List of Contents

Absolute Failure Prescription can only be obtained from the Chaos Medicine Box, a treasure chest with red smoke that appears from time to time in any domain.
You must have the Pleasant Surprise node from the Inspiration Circuit for the box to appear. Upon opening the box, you will have a chance to get the Curio randomly.

Use Inspiration to unlock the Pleasant Surprise Node in the Inspiration Circuit, which allows the Chaos Medicine Box to appear in domains.

Additionally, obtaining the Struggling Color Curio guarantees the appearance of the Chaos Medicine Box so it is good to have if you are searching for it.
| Absolute Failure Prescription | |
|---|---|
Absolute Failure Prescription |
|
| Rarity | Negative Curio |
| Effect | In order to halt the continuation of the war, prescriptions will be tailored to induce varying degrees of hallucinations and disruptions based on the patients' etiology. |
| All Curio Effects |
|---|
| Advance all enemies by 100% when you enter battle. |
| 150% base chance to Freeze all allies when you enter battle. |
| 150% base chance to apply Bleed to all allies for 20% of their max HP for 5 turn(s) when you enter battle. |
| When allies are attacked for the first time each battle, they also lose HP equal to 50% of their current HP. |
| Allies lose 50% of current HP when you enter battle. |
| Gain a 99% DMG debuff for 1 turn when entering battle. |
| Gain a 100% debuff to your Weakness break Efficiency for 1 turn when entering battle. |
| Lose all SP and Energy when you enter battle. |
When you obtain the Absolute Failure Prescription Curio, it is randomly assigned one of these effects.

| Simulated Universe Guides | |||
|---|---|---|---|
| All Simulated Universe Paths | ||
|---|---|---|
Propagation |
Preservation |
Abundance |
Nihility |
The Hunt |
Remembrance |
Destruction |
Elation |
Erudition |
| Simulated Universe: The Swarm Disaster Guides | |
|---|---|
| The Swarm Disaster Guide | How to Unlock All Chapters |
| Communing Trail and Pathstrider Guide | Exploration Guide |
| How to Clear Difficulty 5 | |
| Simulated Universe: Gold and Gears Guides | |
|---|---|
| Gold and Gears Guide | How to Unlock All Trailblaze and Aeon Secrets |
| Neural Network Guide | Dice Customization and All Dice Faces |
| How to Beat Difficulty 5 | |
| Simulated Universe: Unknowable Domain | |
|---|---|
| Unknowable Domain Guide | How to Beat Someone's Mausoleum |
| Simulated Universe Guides | |
|---|---|
| List of All Paths | Simulated Universe Events |
| List of All Curios | Resonance Interplay Guide |
| Herta Store Event Light Cones | |
How to Get Absolute Failure Prescription



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