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Dead Space Remake (2023)

Chapter 5: Lethal Devotion Walkthrough, Interactive Map, and Collectibles

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★ Update 1.04 is out on all platforms as of Feb. 3, 2023!
★ Check our Beginner's Guide for the best tips and tricks!
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★ Perform a ritual for a secret text log and more!
★ How to Unlock Master Override: All RIG Locations
┗Marker Locations | Master Override Doors

Dead Space Remake - Chapter 5 - Lethal Devotion.png

Lethal Devotion is the fifth chapter of Dead Space Remake (2023)'s main story. Read on for a detailed walkthrough, list of rewards, tips for completion, Lethal Devotion Schematic Locations, as well as other strategies!

Previous Chapter Next Chapter
Obliteration Imminent Environmental Hazard

List of Contents

Chapter 5: Lethal Devotion Collectible Locations

Interactive Collectibles Map

Weapon and Upgrade Locations

Weapon/Upgrade Location
Dead Space Remake - Line Gun WeaponLine Gun Found inside the Emergency Equipment Storage at the Medical Deck.
Dead Space Remake - Pulse Rifle WeaponPulse Rifle Dropped by a dying security officer once you reach the Tram Station in the Medical Deck.
Dead Space Remake - Kinesis Module ModuleKinesis Module Found on top of a crate as you enter the Medical Cargo Depot at the start of Chapter 2.
Dead Space Remake - Stasis Pack SchematicStasis Pack Schematic found in the Main Lab Changing Room in Chapter 2, after clearing the quarantine.
Dead Space Remake - Pulse Rounds SchematicPulse Rounds Schematic found inside the Coolant Pipelines room in Chapter 2, to your immediate left after leaving the oxygenless area.
Dead Space Remake - Line Racks SchematicLine Racks Schematic found inside the Dr. B. Warwick - CPO room in the hallway leading to Zero-G Therapy in Chapter 5. Requires Security Clearance Level 2.
Dead Space Remake - Cartridge Rack UpgradeCartridge Rack Found inside the Ishimura Clinic in Chapter 2, on top of the seats on the left side of the room.
Dead Space Remake - Portable Heliotron UpgradePortable Heliotron Found inside the Bioprosthetics Locker Room past the Main Lab Changing Room in Medical. Requires Security Clearance Level 3.
Dead Space Remake - Photon Energizer UpgradePhoton Energizer Found inside the Lab Storage room near Cryogenics in Medical. Requires Security Clearance Level 3.
Dead Space Remake - Marker Fragment 2 Fragment 2Marker Fragment 2
Dead Space Remake - Marker Fragment 5 Fragment 5Marker Fragment 5
Dead Space Remake - Marker Fragment 6 Fragment 6Marker Fragment 6
Related Guides
All Weapon Locations All Weapon Upgrade Locations

Log Locations

Log Event Trigger
Dead Space Remake - Calculated Risks Text LogCalculated Risks Found on top of a surgical bed inside the Medical Deck Observation Room.
Dead Space Remake - They Defy Death Itself Audio LogThey Defy Death Itself Found in a bathroom cubicle at the lower level of the Medical Deck’s Main Lab.
Dead Space Remake - Marker Discovery Text LogMarker Discovery Found on top of a table inside Dr. T. Kyne’s Office.
Dead Space Remake - NicoleNicole's Log Found on the desk inside Dr. Nicole Brennan’s Office in the Main Lab of the Medical Deck.
Dead Space Remake - Anonymized Transcript Text LogAnonymized Transcript Found on a shelf inside Dr. Nicole Brennan’s Office in the Main Lab of the Medical Deck.
Dead Space Remake - Vital Personnel Text LogVital Personnel Found on a desk inside the Biological Prosthetics Center of the Medical Deck.
Dead Space Remake - Patient Observations Text LogPatient Observations Found on one of the medical beds inside the Emergency Room.
Dead Space Remake - NicoleNicole's Study Found on an operating table hidden behind the shower in the Emergency Room.
Dead Space Remake - Rats in the Walls Audio LogRats in the Walls Found by interacting with the mail terminal just beside the door to the Intensive Care Unit in ER Hallway B.
Dead Space Remake - ColonyColony's Problems Found at the end of ER Hallway B, just beside the O2 station.
Dead Space Remake - Autopsy Report Text LogAutopsy Report Found on a desk inside the Morgue.
Dead Space Remake - Patient Harris Audio LogPatient Harris Found on a desk inside the Consultation Room of the Imaging Diagnostics Room.
Dead Space Remake - MercerMercer's Volunteer Found on a desk inside the Medical Deck Observation Room.
Dead Space Remake - Dr. KyneDr. Kyne's Dementia Found in the ER Hallway A, just in front of the room that needs a Leve 2 Security Clearance.
Dead Space Remake - Sterile Instruments Audio LogSterile Instruments Found at the end of ER Hallway B, on a gurney near the O2 Station.
Dead Space Remake - HarrisHarris's Choice Found on a desk in the Intensive Care Unit.
Dead Space Remake - MercerMercer's Journal Found inside Dr. Challus Mercer’s Office.
Dead Space Remake - A Tissue Sample Audio LogA Tissue Sample Triggers after you pick up the Hunter’s tissue sample in Cryogenics.
Dead Space Remake - Marker Fragment 2 Fragment 2Marker Fragment 2
Dead Space Remake - Marker Fragment 5 Fragment 5Marker Fragment 5
Dead Space Remake - Marker Fragment 6 Fragment 6Marker Fragment 6

All Log Locations

Chapter 5: Lethal Devotion Walkthrough

Lethal Devotion Summary

1 Return to the Medical Deck.
2 Locate the Source of the Broadcast.
3 Escape the Creature.
4 Lift the Lockdown.
5 Stop the Poison Gas.
6 Acquire the Liquid Nitrogen.
7 Defeat the Hunter and Return to the Tram Station.

Lethal Devotion Detailed Walkthrough

Objectives
1
Return to Medical Deck
Dead Space Remake placeholder quest iconReturn to the Medical Deck.
After receiving a video log of Nicole, Isaac will prompt to return to the Medical Deck and search for Nicole. Run towards the elevator and get back down to the Main Atrium, then hurry over to the Bridge Tram Station and plot a course to Medical.
2
Locate the Source of the Broadcast
Dead Space Remake placeholder quest iconLocate the Source of the Broadcast.
Go straight to the Security Station where you'll have a conversation with Dr. Challus Mercer. After the conversation ends, go to Imaging Diagnostics Wing. Take the elevator to the Main Lab. Shoot the Yellow Sacs to burst a section of the Necromorph mass.

Pass through the door to Zero-G Therapy but take a left towards the Cryogenics Lab. Take the eleveator down and go into the Chemical Lab to stop the broadcast.
3
Escape the Creature
Dead Space Remake placeholder quest iconEscape the Creature.
After stopping the broadcast, Dr. Mercer will hit you with Stasis and you will be forced to listen to him for a while. After which he will set his creation, the Hunter, a regenerating Necromorph, upon you. This creature cannot be killed by normal means. Your only chance is to cast stasis on it or shoot its limbs as you try to get away.

Once Kendra has the doors unlocked, bolt straight out. Go to Imaging Diagnostic directly from the Chemical Lab and straight to the Security Station.
4
Lift the Lockdown
Dead Space Remake placeholder quest iconLift the Lockdown.
Rush straight to the Emergency Room. Multiple Necromorphs, including the Hunter, will spawn there so be prepared for a fight. Use the Stasis bombs when they are in close proximity to one another for better crowd control. When you can, Kinesis-grab the Power Cell to open the door to ER Hallway A and head to the ICU. A Guardian will be posted by the ICU, take care of it before approaching the ICU. Head inside the ICU towards the Morgue, but take the door to the right of the Morgue elevator to Dr. Mercer's office and lift the lockdown from there.
5
Stop the Poison Gas
Dead Space Remake placeholder quest iconStop the Poison Gas.
When you get out of Mercer's office, a gas toxin will be released into the atmosphere. You have to run back towards the Security Station to bring back life support. There are O2 recharge stations but this will mostly be a simple run towards the Security Station, it is not recommended to fight against any enemy you can avoid easily.
6
Acquire the Liquid Nitrogen
Dead Space Remake placeholder quest iconAcquire the Liquid Nitrogen.
You'll have to go back to Imaging Diagnostic Wing and to the Cryogenics Lab. The Liquid Nitrogen you seek is in the Cryogenic Chamber. When you pick up the item, Dr. Mercer will interrupt once more to deliver his speech, and afterwards he will send his creation to finish you completely.
7
Defeat the Hunter
Dead Space Remake placeholder quest iconDefeat the Hunter.
Much like the original game, your best bet against the Hunter in this situation is to make the most of your environment. Use stasis on the Hunter, while you shoot off its limbs. As it tries to regenerate from within the cryogenic chamber, run to the console to activate the Cryo Freeze process. Afterwards, pick up the Tissue Sample and return to the Medical Tram Station.
►Premeditated Malpractice Side Mission Guide

Chapter 5: Lethal Devotion Tips and Strategies

Do Not Approach Guardians

Guardians usually appear attached to walls or hallways, and fire ranged Necromorphs that will use a tentacle to attack you. Getting too close to a Guardian is certain death. Instead, use your Kinesis Module to throw explosives at its stomach to kill it.

How to Beat Guardians

Do Not Engage the Hunter

Once you reach the Chemical Research Lab, this will be the first time you face the Hunter. It may look like a Slasher on steroids, but this is a Necromorph like no other. It has regenerative abilities so you cannot kill it. Shooting off its limbs only slows it down momentarily. Your only option is to hit it with your Stasis Module to slow its regeneration process, and run while you can.

Use Stasis to Conserve Ammo

Once the Life Support System is compromised, you will be prompted to run to the Security Station to turn it back on. You will have to go back through Medical and face the Hunter along with two Pregnants. Don't bother shooting the Necromorphs as it will only consume time you don't have. Instead use stasis to slow them down and make your way to the other side of the room.

Lure the Hunter into the Cryo Chamber

After dealing with the other Necromorphs, lure the Hunter into the Cryo Chamber and begin dismembering its legs. When it goes down, use Kinesis to slow it down as you race to the control panel and jumpstart the Cryo Chamber.

Chapter 5: Lethal Devotion Enemies Encountered

List of Necromorphs
Dead Space Remake (2023)- Guardian Guardian Weak Spots: Tentacles
Weaknesses: Explosives
Dead Space Remake (2023)- Hunter Hunter Weak Spots: None Specific
Weaknesses: Stasis
Dead Space Remake (2023)- Lurker Lurker Weak Spots: Tentacles
Weaknesses: None
Dead Space Remake (2023)- Pregnants Pregnants Weak Spots: Limbs
Weaknesses: Stasis
Dead Space Remake (2023)- Swarmers Swarmers Weak Spots: None Specific
Weaknesses: Stasis, Explosives, Fire

Dead Space Remake Related Guides

Sample Partial Banner.png

Full Story Walkthrough: All Chapters

Main Missions

All Story Chapters
New Arrivals
(Chapter 1) 		Intensive Care
(Chapter 2)
Course Correction
(Chapter 3) 		Obliteration Imminent
(Chapter 4)
Lethal Devotion
(Chapter 5) 		Environmental Hazard
(Chapter 6)
Into the Void
(Chapter 7) 		Search and Rescue
(Chapter 8)
Dead on Arrival
(Chapter 9) 		End of Days
(Chapter 10)
Alternate Solutions
(Chapter 11) 		Dead Space
(Chapter 12)

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