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Hollow Knight: Silksong

Advanced Alchemy Walkthrough

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☆ Walkthrough in Progress: Bookmark for Updates!
★ Best Crest Builds | Best Tools
☆ Full Interactive Map of Pharloom!
★ Mask Shards | Spool Fragments | Abilities
☆ Boss Guides: The Unravelled | First Sinner
★ Wishes: Broodfeast | The Lost Fleas

Advanced Alchemy Walkthrough

Advanced Alchemy is a Gather Wish in Hollow Knight: Silksong. Read on to see a full walkthrough to completing the side quest, rewards, how to start and its objectives.

List of Contents

How to Start Advanced Alchemy

Speak to Alchemist Zylotol in the Wormways

Alchemist Zylotol Location

The Advanced Alchemy Wish can be started by speaking to Alchemist Zylotol in the Wormways. This wish is only accessible in Act 3.

Wormways 100% Map Guide

How to Complete Advanced Alchemy

Deliver 10 Plasmified Blood

Extract Plasmified Blood

To complete this wish, players will have to collect Plasmified Blood from enemies infected with Plasmium. These enemies can be found along the Wormways, and fire blue projectiles at Hornet.

To extract the Plasmium, players must equip the Needle Phial and hold down the assigned input until it finishes charging. When it lands on an infected enemy, Hornet will stick the Needle Phial and extract one vial of Plasmium Blood.

Advanced Alchemy Rewards

Receive the Plasmium Gland

Plasmium Gland

For completing this Wish, Hornet will receive the Plasmium Gland from Alchemist Zylotol. This upgrade item allows Hornet to infinitely replenish her Plasmium Phial anywhere, for free.

Advanced Alchemy Details

Task Information and Location

Quest Giver Alchemist Zylotol
Quest Location Wormways
Objective(s) Deliver 10 Plasmified Blood vials to Alchemist Zylotol
How to Unlock Talk to the Alchemist in Wormways

Advanced Alchemy is a Gather Task provided by Alchemist Zylotol in the Wormways. Players will be given a Needle Phial which they need to use to extract Plasmified Blood from infected enemies.

Hollow Knight: Silksong Related Guides

Wishes

All Wish Locations and Rewards

All Wishes

Bone Bottom Repairs A Lifesaving Bridge An Icon of Hope
Garb of the Pilgrims Berry Picking The Lost Fleas
Volatile Flintbeetles The Terrible Tyrant Flexile Spines
Bugs of Pharloom Restoration of Bellhart Bellhart's Glory
Pinmaster's Oil Silver Bells My Missing Courier
My Missing Brother Bone Bottom Supplies Pilgrim's Rest Supplies
Songclave Supplies Liquid Lacquer Queen's Egg
Crawbug Clearing Savage Beastfly Rite of the Pollip
Rite of Rebirth Infestation Operation Alchemist's Assisant
Roach Guts Building up Songclave Strengthening Songclave
Courier's Rasher Fine Pins The Wandering Merchant
The Lost Merchant Cloaks of the Choir The Wailing Mother
Great Taste of Pharloom Balm for the Wounded Final Audience
Broodfeast Trail's End Silk and Soul
Fatal Resolve Fastest in Pharloom Hero's Call
Pain, Anguish, and Misery The Hidden Hunter Ecstasy of the End
Passing of the Age Dark Hearts Advanced Alchemy

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