Enemy Changes
Antique Coins
Mr. Raccoon
Files
All Upgrade Locations
BSAA Container
This survey will take about 1 minute.
Your answers will help us to improve our website.
Resident Evil Requiem (RE9)
Insanity Difficulty Guide
★ Join the Investigation: Final Puzzle Solution
☆ Roulette Wheel Solution
★ Antique Coins | Mr. Raccoons | Files
☆ (Typewriters) Save Points: How to Save
★ Post Game | Infinite Ammo
☆ Resident Evil: The Whole Story Explained
This is a guide to the Insanity DIfficulty, the hardest difficulty in Resident Evil Requiem (RE9). Find out how Insanity compares to the other difficulties, and get tips on how to beat it.
List of Contents
Insanity Difficulty Differences
|
|
Enemy Changes
In addition to appearing in greater numbers and having more durability, enemies move much faster and more aggressively. Players will have less time to decide whether to fight or flee and will need to act faster than usual.
It should be noted that more shots are required to stagger them, which significantly increases the difficulty of combat.
Blister Heads Appear More Often
Be prepared to face more Blister Heads, which appear much more frequently and as early as Leon's introductory sequence. This is in stark contrast to lower difficulties, where they appear later inside the care center.
Normal zombies can mutate into Blister Heads on the spot after being killed, which makes them much more dangerous.
Different Item Placement
| Standard | Insanity |
|---|---|
 |
 |
Some items won't be in the same place as in Standard Difficulty, which makes certain sections much harder to play through in Insanity Mode.
The Supply Crate Is Available at the Start
The Supply Crate is available as soon as Leon becomes playable, giving him immediate access to his full arsenal, provided that he has credits to spend.
This makes completing the challenges on lower difficulties much more rewarding, since the rewards you purchase can be used for Insanity difficulty runs.
All Challenges and How to Complete
Ink Ribbons Are Required To Save Progress
The save limitation, previously exclusive to the Standard Classic difficulty run, has now been extended to the Insanity Difficulty setting. Players must now use Ink Ribbons to save their progress.
Safe Code Changes
| Safe Location | Insanity Difficulty Code |
|---|---|
| Examination Room Safe | Right 20, Left 50, Right 30 |
Safe codes have been changed, and you would have to check the various notes and files once again across the areas in order to open the safes.
All Safe Code Solutions and Locations
Insanity Difficulty Tips
|
|
Plan Your Route
Given the limited inventory space, scarce resources, and increased threat posed by the enemies, it is advisable to plan your route in as safe a manner as possible, taking only the bare minimum resources necessary to minimize backtracking.
This includes using the available resources to their fullest potential, taking calculated risks in certain sections, and using skips to increase efficiency.
Unlock Post-Game Weapons and Items
| Reward | CP Cost | Usage |
|---|---|---|
|
Freya's Needle
(Grace) |
4000 CP | Best used alongside infinite ammo, allowing you to hose down zombies with a barrage of bullets. |
|
Kotetsu
(Grace) |
5000 CP | Utilized to save yourself when grabbed. |
 Ghost Grudge
(Leon) |
1000 CP | Fast re-centering speed, and can be used in sections where Leon doesn't have the Requiem. |
 Clatter Carbine
(Leon) |
6000 CP | An Assault Rifle that uses Machinegun bullets, with significantly higher stats than any Submachine Gun. |
 Mortal Edge
(Leon) |
3000 CP | Stronger and more durable than the Hatchet, with a better parry window. |
|
RPG-7
(Leon) |
15000 CP | Deals devestating damage and best used against difficult boss fights. |
| Matsuoka Master Manual (Grace) |
1000 CP | Minimizes backtracking and lets you carry more Infected Blood at a time. |
| Infinite Ribbon (Grace) |
Complete the main story in 4 hours. | Provides infinite saves, letting you re-do specific sections until you get the desired outcome. |
| Tactical Tracker (Leon) |
3000 CP | Provides more Credits when slain, letting you purchase more items in the Supply Crate. |
You can unlock helpful items to aid you in Insanity difficulty runs by completing challenges. This makes certain sections of the game easier since some post-game items are more powerful.
Unlock Weapon Tuning
In order to unlock additional weapon attachments, you to unlock weapon tuning. Once this is done, the weapon can be attached to the final level, thus reaching its maximum potential.
To unlock it, it is necessary to destroy all 25 Mr. Racoon Statues in the game.
All Mr. Raccoon Statue Locations
Invest in Survivability
The substantial increase in the enemy's damage output has made survival significantly more challenging, and Grace can even die immediately on full health upon being grabbed by a regular zombie.
Steroids and Body Armor are much more valuable at the Insanity difficulty level; they can often determine the difference between life and death in most scenarios.
Unlock Infinite Ammo
Unlocking infinite ammo can make difficult sections riddled with enmies much easier, since you won't need to rely solely on stealth anymore.
It also eases the burden of inventory management by eliminating the need to carry extra ammo for each gun in your inventory.
That being said, the enhanced enemies mean that every encounter can still be dangerous, so caution must still be exercised during combat.
How to Unlock Insanity Difficulty
Complete the Game on Any Difficulty
Insanity difficulty is automatically unlocked after you finish the game once, regardless of any difficulty, and ending.
If you want to unlock Insanity Difficulty as soon as you can, you can play the game on the Casual difficulty setting to do it much faster.
Resident Evil Requiem (RE9) Related Guides
Recommended Guides
Wiki Contents
 Story Walkthrough |
 Weapons |
 Bosses |
 Interactive Map |
 Safe Codes |
 Tips and Tricks |
 Puzzles |
 Endings |
 Items |
 Charms |
 Weapon Upgrades |
 Costumes |
 Characters |
 Skips |
 News and Game Info |
- |
Comment
Author
Insanity Difficulty Guide
Please participate in our site
improvement survey
03/2026
improvement survey
03/2026
Would you assist in
improving Game8's site?
improving Game8's site?
×
We are listening to our users' valuable opinions and discussing how to act on them.
The information collected through this survey will be used for the purpose of improving our services. In addition, the information will only be disclosed a part of a statistic in a format that will not allow identification of personal information.
Begin Survey
Not Now
×
Please rate each item regarding Game8.co's Advertisements.
Amount of Ads
Very Dissatisfied
Somewhat Dissatisfied
Fine
Somewhat Satisfied
Highly Satisfied
Placement of Ads
Timing of Ad Display
Ad Loading Speed
Safeness of Ads
Content of Ads
×
Please rate each item regarding Game8.co's Quality of Articles.
Amount of information
Very Dissatisfied
Somewhat Dissatisfied
Fine
Somewhat Satisfied
Highly Satisfied
Frequency of updates
Speed of new information
Accuracy of articles
Understandibility of articles
Readability of sentences
×
Please rate each item regarding Game8.co's Usability of the Site.
Ease of finding information
Very Dissatisfied
Somewhat Dissatisfied
Fine
Somewhat Satisfied
Highly Satisfied
Loading Speed
Use of Color
Font Size
Visibility of Images
Easy to Understand Layout
×
Please rate each item regarding Game8.co's Message Boards, Comments.
Ease of Writing
Very Dissatisfied
Somewhat Dissatisfied
Fine
Somewhat Satisfied
Highly Satisfied
Readability
Ease in Finding Information
Comment Quality
Comment Quantity
Admin Response
×
Please rate each item regarding Game8.co's Site's new design.
Please rate our site's new design
Very Dissatisfied
Somewhat Dissatisfied
Fine
Somewhat Satisfied
Highly Satisfied
Do you think that the website's design change makes the site easier to use?
Has the new design made it easier for you to find information on the site?
Has the new design improved the overall visual appeal of the site?
How would you rate your overall satisfaction with the new design of the site?
×
How likely are you to recommend Game8 to someone you know?
Very Unlikely
0
1
2
3
4
5
6
7
8
9
10
Very Likely
If you have other opinions regarding potential improvement to the website, please share them with us. We would appreciate your honest opinion.
Note: This is a free response section, so you can proceed without entering anything.
Note: Please be sure not to enter any kind of personal information into your response.
Note: Please be sure not to enter any kind of personal information into your response.
×
Thank You
×
Thank you for participating in our survey! Your answers will help us to improve the quality of our website and services.
We hope you continue to make use of Game8.
We hope you continue to make use of Game8.
Close
Premium Articles
Rankings
- We could not find the message board you were looking for.
Gaming News
Popular Games
Genshin Impact Walkthrough & Guides Wiki
Resident Evil Requiem (RE9) Walkthrough & Guides Wiki
Honkai: Star Rail Walkthrough & Guides Wiki
Monster Hunter Wilds Walkthrough & Guides Wiki
Umamusume: Pretty Derby Walkthrough & Guides Wiki
Pokemon TCG Pocket (PTCGP) Strategies & Guides Wiki
Arknights: Endfield Walkthrough & Guides Wiki
Wuthering Waves Walkthrough & Guides Wiki
Zenless Zone Zero Walkthrough & Guides Wiki
Digimon Story: Time Stranger Walkthrough & Guides Wiki
Recommended Games
Diablo 4: Vessel of Hatred Walkthrough & Guides Wiki
Fire Emblem Heroes (FEH) Walkthrough & Guides Wiki
Pokemon Brilliant Diamond and Shining Pearl (BDSP) Walkthrough & Guides Wiki
Super Smash Bros. Ultimate Walkthrough & Guides Wiki
Yu-Gi-Oh! Master Duel Walkthrough & Guides Wiki
Elden Ring Shadow of the Erdtree Walkthrough & Guides Wiki
Monster Hunter World Walkthrough & Guides Wiki
The Legend of Zelda: Tears of the Kingdom Walkthrough & Guides Wiki
Persona 3 Reload Walkthrough & Guides Wiki
Cyberpunk 2077: Ultimate Edition Walkthrough & Guides Wiki
All rights reserved
©CAPCOM U.S.A., INC. ALL RIGHTS RESERVED.
The copyrights of videos of games used in our content and other intellectual property rights belong to the provider of the game.
The contents we provide on this site were created personally by members of the Game8 editorial department.
We refuse the right to reuse or repost content taken without our permission such as data or images to other sites.