The Callisto Protocol

Ending Explained

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The Callisto Protocol - Ending Explained
The ending of The Callisto Protocol provides more questions than answers to players who have finished the game. Read on to understand what happened in the ending and what it means for the game's future.

News.pngHeads Up! This article contains spoilers for the ending sequence of The Callisto Protocol.

The Callisto Protocol Ending Explained

Jacob Completes the Antidote

The Callisto Protocol - Jacob Completes the Antidote
After taking down the mutated Ferris, Jacob immediately runs up to his corpse and extracts a sample from his eyeball. Doing this completes the antidote he needs to save Dani from becoming fully infected.

Warden Cole Was A Hologram

The Callisto Protocol - Warden Cole Was A Hologram
Immediately after, Warden Cole attempts to persuade Jacob to give him the sample, offering an escape pod in exchange. However, Dani interrupts the two by shooting the Warden, inadvertently revealing that he was a hologram all along.

The Protocol Moves Forward

The Callisto Protocol - The Protocol Moves Forward
Disregarding Warden Cole's words, Jacob saves Dani by injecting her with the antidote. This act displeases Cole, but he quickly brushes it off as the data obtained from the events at Black Iron Prison "will carry the Protocol to the next phase." This quote suggests that The Callisto Protocol could receive an expansion or sequel in the future.

Jacob Sacrifices Himself

Jacob Sacrifices Himself
As Warden Cole leaves, he starts a self-destruct sequence, forcing Jacob and Dani to run to the escape pods. Jacob reaches the evacuation bay first but finds only one escape pod left.

Wanting to atone for his involvement in the events on Europa, Jacob sacrifices himself by shoving Dani into the pod and sending her to safety. However, he also left Dani a parting gift: a Biophage larva that she can use to expose the truth.

Jacob Might Survive

The Callisto Protocol - Jacob Might Survive
The scene cuts back to Jacob, exhausted after fending off waves of Biophage. While it seems like all hope is lost, Dr. Mahler's hologram shows up and tells Jacob that "there might be a way out after all," which again suggests that there may be more in store for The Callisto Protocol in the future.

Potential Setup for Future Content

The Callisto Protocol - Story DLC
Overall, the ending of The Callisto Protocol provides many open doors that the developers could take for future game content, especially considering the words of Warden Cole and Dr. Mahler.

We may receive more answers when the Story DLC, part of the game's Season Pass, arrives in Summer 2023.

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The Callisto Protocol Related Guides

Callisto Protocol - Tips and Tricks

Tips and Tricks:
Beginner's Guide to The Callisto Protocol

All Tips & Tricks

Skins and Cosmetics
List of Skins How to Get the Biophage Skin
How to Get the Retro Prisoner Skin How to Get the Founder's Pack
How to Get the Engineer Skin How to Get Watchtower Skin
How to Get Outer Way Skin -
Game Mechanics & Upgrades
All Reforge Weapon Upgrades Inventory Upgrade Guide
How to Get Armor How to Heal
How to Farm Callisto Credits Ammo Farming Guide
How to Perform a Quick Kill -
Weapons & Combat
Best Upgrades Guide Gun Controls Guide
How to Dodge Melee Attacks How to Block
Best Weapons Guide Perfect Dodge Guide
System / FAQs
Difficulty Settings Guide Best Settings Guide
New Game Plus Guide Season Pass Price and Contents
All Permanent Events and Missable Content List of All Death Animations/Scenes
How to Fix Stuttering and Frame Rate Issues Can You Save the Trapped Worker?
How to Pre-Load How to Fix Low Quality Text
How to Use Photo Mode Is There a Map?
How to Reset Checkpoints Contagion Mode Guide
How to Save: Can You Turn Off Autosave? What are Beta Paths?
All Weapon Schematic Locations Ending Explained
Can You Quick Turn? Can You Skip Cutscenes?
List of Unlockables -

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