This page lists all of the puzzles in the game Resident Evil 3 Remake (RE3 Remake). Read on to find where you will encounter them and their solutions!

Train Route Puzzle

After restoring the power at the Substation, you will have to come back to the Subway Office to plan the route for the train in order to progress the story.

Solution

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The Subway Control Room puzzle answer can be seen on the board in front of you. You need to connect the start and the end of the line by using the available routes for the train.

Train Route Puzzle Solution

Jewel Puzzle

You can place Jewels from the Fancy Box into the Monument in the Subway Station. Everytime you place a Jewel into the Monument, you will receive an item that will help you progress the game.

Fancy Box 1

Area	Map
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Inside the ToyUncle Store on top of the table. You will need the lockpick to access this area.
★Location: ToyUncle Store ★Chart: Downtown

Fancy Box 2

Area	Map
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Inside the Grocery Store near the counter. You will need the Bolt Cutters to access this area.
★Location: Grocery Store ★Chart: Downtown

Fancy Box 3

Area	Map
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Inside the safe room in the Donut Shop.
★Location: Donut Shop ★Chart: Downtown

Rewards

Where to Find the Jewels

Vaccine Puzzle

To create the Vaccine, you must first obtain the two solutions needed to create the Vaccine Base. These solutions can be obtained in these areas:

Culture Sample

Item Name	Map
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★Location: Lab 1 ★Chart: Nest 2

Liquid Filled Test Tube

Item Name	Map
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★Location: Incubation Lab ★Chart: Nest 2

Once you have all the solutions, combine them and solve the puzzle using the Vaccine Equipment.

Solution

Vaccine Puzzle Solution

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