Nest 2 Walkthrough | Resident Evil 3 Remake (RE3)

Nest 2.jpg
This walkthrough will take you through the Nest 2 area of Resident Evil 3 Remake (RE3 Remake). For tips and strategies, as well as a list of items and Mr. Charlie Dolls that can be found, read on.

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Underground Storage

Nest 2 - Walkthrough Chart

Nest 2 2F Nest 2 1F
Nest 2 B1 Nest 2 B2
Clear Time: 40 Minutes
1 Go to the 2nd Floor and get the Flash Drive.
2 Go to the Incubation Lab by going through the locked door on the 1st Floor.
3 Get the Liquid-filled Test Tube.
4 Go to the Lab and get the Culture Sample.
5 Combine Liquid-filled Test Tube and Culture Sample.
6 Go back to the 2nd Floor and make the Vaccine.
Vaccine Puzzle Solution
7 Get the Vaccine.
8 Escape the facility.
9 Defeat Nemesis Second Form.
10 A cutscene with Nicholai will start, then you must defeat Nemesis Final Form.
11 Climb the ladder and follow Nicholai.
12 Escape Raccoon City using a helicopter.

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Using Flame Rounds

Jil IconGame8 Team Flame Rounds are extremely effective against almost all the enemies that you will encounter in Nest 2. Make sure that you are combining Explosive A and Explosive C to get Flame Rounds. Flame Rounds are only weak against Hunter Beta, so keep this in mind to use the correct Ammo to deal with different types of enemies. This will help you conserve more ammo for the boss fights later in the game.

Things to Do in Nest 2

Get the Flash Drive

Override Key.jpg
You must first get the flash drive to have access to the rooms containing the solutions needed for the Vaccine. You can get the Flash Drive at the computer on the 2nd floor.

Collect the Solutions

Liquid-filled test tube.jpg
Go to the 1st Floor and open up locked door near the safe area. This area connects you to all the places you need to go in order to obtain the solutions on the 2nd Floor.

Get the Vaccine

Once you have all the solutions, combine them and head back to the 2nd Floor where you got the Flash Drive. Use the device and synthesize them to create the Vaccine.

Vaccine Puzzle Solution

Location of Mr. Charlie Dolls in Nest 2

Location Map
★ Location: Left corner of the balcony near the machine where you get the Flash Drive on the 2nd Floor.
Location Map
★ Location: Small room next to the Culture Sample at the 2nd Floor.

Location of All Mr. Charlie Dolls

Available Items and Trophies in Nest 2

List of Available Items

Item Location

Enemies in Nest 2

How to Beat Pale Heads

Pale Head
Pale Heads.jpg
Location: Nest 2
Recommended Weapon: Shotgun
Checkmark.pngPale Heads regenerate HP from minor damage, so try to use a more powerful weapon than a handgun. Using your shotgun is the most efficient way to deal damage because of the spread, which also helps you deal with the Pale Heads' quick movements.

How to Beat Pale Heads

How to Beat Nemesis' 2nd Form

Stage 2 Nemesis
Nemesis 2nd Form.jpg
Location: Nest 2
Recommended Weapon: Grenade Launcher Flame Rounds
Checkmark.pngUse Flame Rounds to quickly make Nemesis flee and run around the tanks. Listen to Carlos very carefuly when Nemesis flees away to hide. Carlos will tell you where he is hiding, so shoot the tank where Nemesis is hiding to electrocute him. This will expose his weakness and stun him for a few seconds. Use this time to deal massive damage on Nemesis to make the fight much easier.

How to Fight Nemesis (2nd Form)

How to Beat Nemesis' Final Form

Stage 3 Nemesis
Nemesis Final Form.jpg
Location: Nest 2
Recommended Weapon: Magnum
Checkmark.pngAim for the red glowing parts around Nemesis' body using your Magnum. If you manage to break all the glowing parts on his body he will be staggered for a few seconds. Use this time to recharge the energy source to deliver the final blow.

How to Fight Nemesis (Final Form)

Related Links

Prev Walkthrough
Underground Storage
No. Walkthrough Section Clear Time
Opening 15 minutes
Downtown 20 minutes
Substation ~ Subway Office 40 minutes
Sewers ~ Subway 40 minutes
Police Station 30 minutes
Subway Tunnel ~ Clock Tower 15 minutes
Hospital 70 minutes
Underground Storage 25 minutes
Nest 2 40 minutes
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    • Anyone still alive? Hahahaha. I hope this pandemic doesn't evolve into a zombie apocalypse.

    • I can see marketing elements in the new part of the game. Currently, it is becoming more and more popular. All in all, I am not surprised it is a way to get extra money for game developers. For more information on marketing in games, see this article:

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